Non-rigid Registration of Vascular Structures for Aligning 2D X-ray Angiography with 3D CT Angiography

The alignment of pre-operative 3D scans with intra-operative 2D images is important for providing better image guidance. Specifically, overlaying the 3D centerlines of coronary arteries on top of X-ray angiography images reduces the uncertainty inherent in 2D images used during cardiovascular interventions. Because of the dynamic cardiovascular motion from the heartbeat and respiration, a non-rigid registration approach should be applied in contrast registration of the static vascular structure. In this paper, a modified TPS-RPM method is adopted as a non-rigid registration based on a feature-based approach. The proposed method is evaluated on 12 clinical datasets to highlight the necessity of a non-rigid registration approach.

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