Top-Down Modulation of the Auditory Steady-State Response in a Task-Switch Paradigm

Auditory selective attention is an important mechanism for top-down selection of the vast amount of auditory information our perceptual system is exposed to. In the present study, the impact of attention on auditory steady-state responses is investigated. This issue is still a matter of debate and recent findings point to a complex pattern of attentional effects on the auditory steady state response (aSSR). The present study aimed at shedding light on the involvement of ipsilateral and contralateral activations to the attended sound taking into account hemispheric differences and a possible dependency on modulation frequency. In aid of this, a dichotic listening experiment was designed using amplitude-modulated tones that were presented to the left and right ear simultaneously. Participants had to detect target tones in a cued ear while their brain activity was assessed using MEG. Thereby, a modulation of the aSSR by attention could be revealed, interestingly restricted to the left hemisphere and 20 Hz responses: contralateral activations were enhanced while ipsilateral activations turned out to be reduced. Thus, our findings support and extend recent findings, showing that auditory attention can influence the aSSR, but only under specific circumstances and in a complex pattern regarding the different effects for ipsilateral and contralateral activations.

[1]  W. Schlee.  Single-trial neuromagnetic analysis of auditory steady state responses and its application for the studies of chronic tinnitus , 2006 .

[2]  F. L. D. Silva,et al.  Event-related EEG/MEG synchronization and desynchronization: basic principles , 1999, Clinical Neurophysiology.

[3]  C. Pantev,et al.  Tonotopic organization of the sources of human auditory steady-state responses , 1996, Hearing Research.

[4]  T. Elbert,et al.  Abnormal auditory mismatch response in tinnitus sufferers with high-frequency hearing loss is associated with subjective distress level , 2004, BMC Neuroscience.

[5]  S. Hillyard,et al.  Electrical Signs of Selective Attention in the Human Brain , 1973, Science.

[6]  D. Bates,et al.  Mixed-Effects Models in S and S-PLUS , 2001 .

[7]  Andreas Keil,et al.  The neural correlates of feature-based selective attention when viewing spatially and temporally overlapping images , 2007, Neuropsychologia.

[8]  P. Fries,et al.  Is synchronized neuronal gamma activity relevant for selective attention? , 2003, Brain Research Reviews.

[9]  Timothy Edward John Behrens,et al.  Functional Asymmetry for Auditory Processing in Human Primary Auditory Cortex , 2003, The Journal of Neuroscience.

[10]  G. Sperling,et al.  Attentional modulation of SSVEP power depends on the network tagged by the flicker frequency. , 2006, Cerebral cortex.

[11]  Monica Fabiani,et al.  Lagged covariance structure models for studying functional connectivity in the brain , 2006, NeuroImage.

[12]  R. Desimone,et al.  Competitive Mechanisms Subserve Attention in Macaque Areas V2 and V4 , 1999, The Journal of Neuroscience.

[13]  E. Yund,et al.  Attentional modulation of human auditory cortex , 2004, Nature Neuroscience.

[14]  T W Picton,et al.  Human Auditory Steady State Evoked Potentials during Sleep , 1985, Ear and hearing.

[15]  Fred H Hamker,et al.  Modeling feature-based attention as an active top-down inference process. , 2006, Bio Systems.

[16]  C Pantev,et al.  A high-precision magnetoencephalographic study of human auditory steady-state responses to amplitude-modulated tones. , 2000, The Journal of the Acoustical Society of America.

[17]  Matthias M. Müller,et al.  Selective spatial attention to left or right hand flutter sensation modulates the steady-state somatosensory evoked potential. , 2004, Brain research. Cognitive brain research.

[18]  Mary Lou Coad,et al.  Mapping the 40-Hz auditory steady-state response using current density reconstructions , 2005, Hearing Research.

[19]  E. Rolls,et al.  Attention, short-term memory, and action selection: A unifying theory , 2005, Progress in Neurobiology.

[20]  C Pantev,et al.  Right hemispheric laterality of human 40 Hz auditory steady-state responses. , 2005, Cerebral cortex.

[21]  D. Spinelli,et al.  Effects of sustained, voluntary attention on amplitude and latency of steady-state visual evoked potential: a costs and benefits analysis , 2002, Clinical Neurophysiology.

[22]  Maurizio Maurizi,et al.  Generation of human auditory steadystate responses (SSRs). I: Stimulus rate effects , 1995, Hearing Research.

[23]  Peter Ayton,et al.  The hot hand fallacy and the gambler’s fallacy: Two faces of subjective randomness? , 2004, Memory & cognition.

[24]  M. Sarter,et al.  The cognitive neuroscience of sustained attention: where top-down meets bottom-up , 2001, Brain Research Reviews.

[25]  Werner Lutzenberger,et al.  Reciprocal modulation of neuromagnetic induced gamma activity by attention in the human visual and auditory cortex , 2004, NeuroImage.

[26]  Helen J. Neville,et al.  An Event-related Potential Study of Selective Auditory Attention in Children and Adults , 2005, Journal of Cognitive Neuroscience.

[27]  Wolfgang Gaggl,et al.  Differential representation of speech sounds in the human cerebral hemispheres. , 2006, The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology.

[28]  Joseph Ciorciari,et al.  Steady-State Visually Evoked Potential topography associated with a visual vigilance task , 2005, Brain Topography.

[29]  K. Meador,et al.  Functional MRI cerebral activation and deactivation during finger movement , 2000, Neurology.

[30]  Anil K. Seth,et al.  The power of human brain magnetoencephalographic signals can be modulated up or down by changes in an attentive visual task , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[31]  Leslie G. Ungerleider,et al.  Increased Activity in Human Visual Cortex during Directed Attention in the Absence of Visual Stimulation , 1999, Neuron.

[32]  S. Stone-Elander,et al.  Coexistence of Attention-Based Facilitation and Inhibition in the Human Cortex , 1998, NeuroImage.

[33]  Matthias M. Müller,et al.  Magnetoencephalographic recording of steadystate visual evoked cortical activity , 2005, Brain Topography.

[34]  O. Bertrand,et al.  Oscillatory gamma activity in humans: a possible role for object representation. , 2000, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[35]  T. Picton,et al.  Human auditory steady-state responses: Respuestas auditivas de estado estable en humanos , 2003, International journal of audiology.

[36]  Larry E. Roberts,et al.  Frequency organization of the 40-Hz auditory steady-state response in normal hearing and in tinnitus , 2006, NeuroImage.

[37]  T W Picton,et al.  Potentials evoked by the sinusoidal modulation of the amplitude or frequency of a tone. , 1987, The Journal of the Acoustical Society of America.

[38]  John J. Foxe,et al.  Task switching: a high-density electrical mapping study , 2003, NeuroImage.

[39]  K. Hugdahl,et al.  Effects of attention on dichotic listening: An 15O‐PET study , 2000, Human brain mapping.

[40]  T W Picton,et al.  Human auditory steady-state evoked potentials during selective attention. , 1987, Electroencephalography and clinical neurophysiology.

[41]  A. Engel,et al.  Auditory novelty oddball allows reliable distinction of top-down and bottom-up processes of attention. , 2002, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[42]  Arnaud Delorme,et al.  EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis , 2004, Journal of Neuroscience Methods.

[43]  R. Näätänen,et al.  Early selective-attention effect on evoked potential reinterpreted. , 1978, Acta psychologica.

[44]  J Pernier,et al.  Neurophysiological mechanisms of auditory selective attention in humans. , 2000, Frontiers in bioscience : a journal and virtual library.

[45]  K. Lehnertz,et al.  Comparison between simultaneously recorded auditory-evoked magnetic fields and potentials elicited by ipsilateral, contralateral and binaural tone burst stimulation. , 1986, Audiology : official organ of the International Society of Audiology.

[46]  Matthias M. Müller,et al.  Early modulation of visual perception by emotional arousal: Evidence from steady-state visual evoked brain potentials , 2003, Cognitive, affective & behavioral neuroscience.

[47]  Sandra E. Black,et al.  Task-Relevant Modulation of Contralateral and Ipsilateral Primary Somatosensory Cortex and the Role of a Prefrontal-Cortical Sensory Gating System , 2002, NeuroImage.

[48]  S. Hillyard,et al.  Selective attention to stimulus location modulates the steady-state visual evoked potential. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[49]  K Tschopp,et al.  Functional Magnetic Resonance Imaging Is a Non-invasive Method for the Detection of Focal Brain Activity at High Spatial Resolution. Acoustic Stimulation Leads to a Blood Oxygenation Level Dependent , 2022 .

[50]  T. Elbert,et al.  One set of sounds, two tonotopic maps: exploring auditory cortex with amplitude-modulated tones , 2004, Clinical Neurophysiology.

[51]  C Pantev,et al.  Stimulus induced desynchronization of human auditory 40-Hz steady-state responses. , 2005, Journal of neurophysiology.

[52]  G. Conti,et al.  Generation of auditory steady-state responses: linearity assessment. , 1999, Scandinavian audiology. Supplementum.

[53]  S. Yantis,et al.  Visual Attention: Bottom-Up Versus Top-Down , 2004, Current Biology.

[54]  F. Bloom,et al.  Modulation of early sensory processing in human auditory cortex during auditory selective attention. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[55]  Patrick Chauvel,et al.  Temporal envelope processing in the human left and right auditory cortices. , 2004, Cerebral cortex.

[56]  Felix Darvas,et al.  Spatio-temporal source imaging reveals subcomponents of the human auditory mismatch negativity in the cingulum and right inferior temporal gyrus , 2001, Neuroscience Letters.

[57]  S. Makeig,et al.  A 40-Hz auditory potential recorded from the human scalp. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[58]  Alan C. Evans,et al.  Auditory Attention to Space and Frequency Activates Similar Cerebral Systems , 1999, NeuroImage.

[59]  D. Kahneman,et al.  Functional Imaging of Neural Responses to Expectancy and Experience of Monetary Gains and Losses tasks with monetary payoffs , 2001 .

[60]  N. Weisz,et al.  Tracking short-term auditory cortical plasticity during classical conditioning using frequency-tagged stimuli. , 2007, Cerebral cortex.

[61]  Lutz Jäncke,et al.  Attention modulates activity in the primary and the secondary auditory cortex: a functional magnetic resonance imaging study in human subjects , 1999, Neuroscience Letters.

[62]  Giri P. Krishnan,et al.  The effect of selective attention on the gamma-band auditory steady-state response , 2007, Neuroscience Letters.

[63]  S. Yantis,et al.  Visual attention: control, representation, and time course. , 1997, Annual review of psychology.

[64]  Leslie G. Ungerleider,et al.  Mechanisms of directed attention in the human extrastriate cortex as revealed by functional MRI. , 1998, Science.

[65]  M. Scherg,et al.  Intracerebral Sources of Human Auditory Steady-State Responses , 2004, Brain Topography.

[66]  R. C. Oldfield.  The assessment and analysis of handedness: the Edinburgh inventory. , 1971, Neuropsychologia.

[67]  Risto Näätänen,et al.  Hemispheric lateralization of cerebral blood-flow changes during selective listening to dichotically presented continuous speech. , 2003, Brain research. Cognitive brain research.

[68]  Shozo Tobimatsu,et al.  Steady-state vibration somatosensory evoked potentials: physiological characteristics and tuning function , 1999, Clinical Neurophysiology.

[69]  Riitta Hari,et al.  Neuromagnetic Responses to Frequency-Tagged Sounds: A New Method to Follow Inputs from Each Ear to the Human Auditory Cortex during Binaural Hearing , 2002, The Journal of Neuroscience.

[70]  K. Heilman,et al.  Auditory neglect in man. , 1972, Archives of neurology.

[71]  D. Regan,et al.  COMPARISON OF TRANSIENT AND STEADY‐STATE METHODS * , 1980, Annals of the New York Academy of Sciences.

[72]  Daniel Gembris,et al.  Top-down attentional processing enhances auditory evoked gamma band activity , 2003, Neuroreport.

[73]  Marc A Heiser,et al.  Associative learning shapes the neural code for stimulus magnitude in primary auditory cortex. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[74]  N. Chater,et al.  Shedding light on brain function : the event-related optical signal , 2001 .

[75]  Richard S. J. Frackowiak,et al.  Representation of the temporal envelope of sounds in the human brain. , 2000, Journal of neurophysiology.

[76]  K. Reinikainen,et al.  Selective attention enhances the auditory 40-Hz transient response in humans , 1993, Nature.

[77]  David Poeppel,et al.  Systematic latency variation of the auditory evoked M100: from average to single-trial data , 2004, NeuroImage.

[78]  M Maurizi,et al.  40-Hz steady-state responses in newborns and in children. , 1990, Audiology : official organ of the International Society of Audiology.

[79]  Patrick Berg,et al.  Advanced Tools for Digital EEG Review:: Virtual Source Montages, Whole-head Mapping, Correlation, and Phase Analysis , 2002, Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.

[80]  R. B. Silberstein,et al.  Steady-State Visually Evoked Potential Topography during Processing of Emotional Valence in Healthy Subjects , 2002, NeuroImage.

[81]  H Shibasaki,et al.  Role of the primary auditory cortex in auditory selective attention studied by whole-head neuromagnetometer. , 1998, Brain research. Cognitive brain research.

[82]  T. Picton,et al.  The effect of attention on the auditory steady-state response. , 2004, Neurology & clinical neurophysiology : NCN.

[83]  O. Bertrand,et al.  Effects of Selective Attention on the Electrophysiological Representation of Concurrent Sounds in the Human Auditory Cortex , 2007, The Journal of Neuroscience.

[84]  P. Matthews,et al.  Functional MRI cerebral activation and deactivation during finger movement , 2000, Neurology.

[85]  T W Picton,et al.  Human auditory steady state potentials. , 1984, Ear and hearing.

[86]  Claudio Babiloni,et al.  Inhibition of auditory cortical responses to ipsilateral stimuli during dichotic listening: evidence from magnetoencephalography , 2004, The European journal of neuroscience.

[87]  Andreas Keil,et al.  Fear but not awareness predicts enhanced sensory processing in fear conditioning. , 2006, Psychophysiology.

[88]  R. Albera,et al.  Auditory steady-state responses and clinical applications , 2006, European Archives of Oto-Rhino-Laryngology and Head & Neck.

[89]  P. Perruchet.  A pitfall for the expectancy theory of human eyelid conditioning , 1985, The Pavlovian journal of biological science.

[90]  M. Scherg,et al.  Deconvolution of 40 Hz steady-state fields reveals two overlapping source activities of the human auditory cortex , 1999, Clinical Neurophysiology.

[91]  S van de Par,et al.  Binaural processing model based on contralateral inhibition. II. Dependence on spectral parameters. , 2001, The Journal of the Acoustical Society of America.

[92]  T. Picton,et al.  Human auditory steady-state responses to amplitude-modulated tones: phase and latency measurements , 2000, Hearing Research.

[93]  Vinod Menon,et al.  Where and When the Anterior Cingulate Cortex Modulates Attentional Response: Combined fMRI and ERP Evidence , 2006, Journal of Cognitive Neuroscience.

[94]  Matthew Flatt,et al.  PsyScope: An interactive graphic system for designing and controlling experiments in the psychology laboratory using Macintosh computers , 1993 .

[95]  Nobuo Suga,et al.  Sharpening of frequency tuning by inhibition in the central auditory system: tribute to Yasuji Katsuki , 1995, Neuroscience Research.