[Hyaluronic acid: biological role, structure, synthesis, isolation, purification, and application (review)].

Abstract The methods for isolation and purification of hyaluronic acid are summarized. The structural properties of this mucopolysaccharide are discussed, and hyaluronic acid-hydrolyzing enzymes are characterized. Data on the biological role, properties, and content of hyaluronic acid in tissues are reviewed. The possibilities of the application of hyaluronic acid in medicine, cosmetology, veterinary science, and hygiene are discussed.