METTL3 promotes m6A hypermethylation of RBM14 via YTHDF1 leading to the progression of hepatocellular carcinoma

[1]  Bo Shu,et al.  The METTL3/MALAT1/PTBP1/USP8/TAK1 axis promotes pyroptosis and M1 polarization of macrophages and contributes to liver fibrosis , 2021, Cell death discovery.

[2]  Anqi Wu,et al.  Methyltransferase-Like 3-Mediated m6A Methylation of Hsa_circ_0058493 Accelerates Hepatocellular Carcinoma Progression by Binding to YTH Domain-Containing Protein 1 , 2021, Frontiers in Cell and Developmental Biology.

[3]  Hong Zhou,et al.  Advances in RNA Epigenetic Modifications in Hepatocellular Carcinoma and Potential Targeted Intervention Strategies , 2021, Frontiers in Cell and Developmental Biology.

[4]  Xiaomei Wang,et al.  MicroRNA-206 promotes the recruitment of CD8+ T cells by driving M1 polarisation of Kupffer cells , 2021, Gut.

[5]  Xuemei Zhang,et al.  Role of N6-Methyladenosine (m6A) Methylation Regulators in Hepatocellular Carcinoma , 2021, Frontiers in Oncology.

[6]  F. Tacke,et al.  Liver Injury and the Macrophage Issue: Molecular and Mechanistic Facts and Their Clinical Relevance , 2021, International journal of molecular sciences.

[7]  S. Dang,et al.  ANGPTL4 regulates CD163 expression and Kuppfer cell polarization induced cirrhosis via TLR4/NF-κB pathway. , 2021, Experimental cell research.

[8]  G. Ning,et al.  Identification of an m6A-Related Signature as Biomarker for Hepatocellular Carcinoma Prognosis and Correlates with Sorafenib and Anti-PD-1 Immunotherapy Treatment Response , 2021, Disease markers.

[9]  Jun Liu,et al.  m6A RNA Methylation Regulators Elicit Malignant Progression and Predict Clinical Outcome in Hepatocellular Carcinoma , 2021, Disease markers.

[10]  R. Zhao,et al.  METTL3/METTL14 Transactivation and m6A-Dependent TGF-β1 Translation in Activated Kupffer Cells , 2021, Cellular and molecular gastroenterology and hepatology.

[11]  Rui Wang,et al.  The Role of RNA Methyltransferase METTL3 in Hepatocellular Carcinoma: Results and Perspectives , 2021, Frontiers in Cell and Developmental Biology.

[12]  N. Blake,et al.  Dynamics of m6A RNA Methylome on the Hallmarks of Hepatocellular Carcinoma , 2021, Frontiers in Cell and Developmental Biology.

[13]  Yi Luo,et al.  The role of tumor-associated macrophages in primary hepatocellular carcinoma and its related targeting therapy , 2021, International journal of medical sciences.

[14]  Jianhui Jia,et al.  Contributions and Prognostic Values of N6-Methyladenosine RNA Methylation Regulators in Hepatocellular Carcinoma , 2021, Frontiers in Genetics.

[15]  Yu-qin Pan,et al.  Analysis of METTL3 and METTL14 in hepatocellular carcinoma , 2020, Aging.

[16]  Yan-rong Liu,et al.  RNA m6A methylation promotes the formation of vasculogenic mimicry in hepatocellular carcinoma via Hippo pathway , 2020, Angiogenesis.

[17]  Jiao Guo,et al.  Kupffer Cells in Non-alcoholic Fatty Liver Disease: Friend or Foe? , 2020, International journal of biological sciences.

[18]  Chun-Xiao Song,et al.  Mapping the epigenetic modifications of DNA and RNA , 2020, Protein & Cell.

[19]  Gao-Min Liu,et al.  Identification of METTL3 as an Adverse Prognostic Biomarker in Hepatocellular Carcinoma , 2020, Digestive Diseases and Sciences.

[20]  Mengnuo Chen,et al.  The emerging roles of N6-methyladenosine (m6A) deregulation in liver carcinogenesis , 2020, Molecular Cancer.

[21]  Q. Ding,et al.  METTL3-mediated m6A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significance , 2019, Gut.

[22]  Lixin Wei,et al.  Macrophages and hepatocellular carcinoma , 2019, Cell & Bioscience.

[23]  Samie R Jaffrey,et al.  Reading, writing and erasing mRNA methylation , 2019, Nature Reviews Molecular Cell Biology.

[24]  J. Llovet,et al.  Molecular therapies and precision medicine for hepatocellular carcinoma , 2018, Nature Reviews Clinical Oncology.

[25]  Mihoko Kai Roles of RNA-Binding Proteins in DNA Damage Response , 2016, International journal of molecular sciences.

[26]  Amit G Singal,et al.  Hepatocellular Carcinoma From Epidemiology to Prevention: Translating Knowledge into Practice. , 2015, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[27]  B. Ghadimi,et al.  Hepatocellular carcinoma: Surgeon's view on latest findings and future perspectives. , 2015, World journal of hepatology.

[28]  Mihoko Kai,et al.  RNA binding protein RBM14 promotes radio-resistance in glioblastoma by regulating DNA repair and cell differentiation , 2014, Oncotarget.

[29]  A. Phillips,et al.  Switched alternative splicing of oncogene CoAA during embryonal carcinoma stem cell differentiation , 2007, Nucleic acids research.

[30]  Marcel H. Schulz,et al.  Hepatocellular Carcinoma and Nuclear Paraspeckles: Induction in Chemoresistance and Prediction for Poor Survival. , 2019, Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.