Inhibition of Nipah Virus Infection In Vivo: Targeting an Early Stage of Paramyxovirus Fusion Activation during Viral Entry
暂无分享,去创建一个
Min Lu | Heinz Feldmann | Laura M. Palermo | R. Cortese | H. Feldmann | Min Lu | L. M. Palermo | M. Porotto | A. Pessi | A. Talekar | A. Moscona | I. Devito | Anne Moscona | Riccardo Cortese | Antonello Pessi | Matteo Porotto | Christine C. Yokoyama | Jie Liu | Barry Rockx | B. Rockx | Jie Liu | Aparna Talekar | Ilaria DeVito | C. C. Yokoyama | Aparna Talekar | Ilaria DeVito
[1] G. Gao,et al. Crystal structures of Nipah and Hendra virus fusion core proteins , 2006, The FEBS journal.
[2] A. Moscona,et al. The use of a quantitative fusion assay to evaluate HN-receptor interaction for human parainfluenza virus type 3. , 1999, Virology.
[3] Z. Otwinowski,et al. [20] Processing of X-ray diffraction data collected in oscillation mode. , 1997, Methods in enzymology.
[4] T. Weber,et al. Mutations in Human Parainfluenza Virus Type 3 Hemagglutinin-Neuraminidase Causing Increased Receptor Binding Activity and Resistance to the Transition State Sialic Acid Analog 4-GU-DANA (Zanamivir) , 2003, Journal of Virology.
[5] R. Lamb,et al. Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[6] A. Sanchez,et al. A system for functional analysis of Ebola virus glycoprotein. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[7] G. Murshudov,et al. Refinement of macromolecular structures by the maximum-likelihood method. , 1997, Acta crystallographica. Section D, Biological crystallography.
[8] C. Broder,et al. A Neutralizing Human Monoclonal Antibody Protects against Lethal Disease in a New Ferret Model of Acute Nipah Virus Infection , 2009, PLoS pathogens.
[9] Kelly J. Henrickson. Parainfluenza Viruses , 2003, Clinical Microbiology Reviews.
[10] S. Rusconi,et al. Alpha complementation of LacZ in mammalian cells. , 1996, Nucleic acids research.
[11] T. Matthews,et al. Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[12] Laura M. Palermo,et al. Human Parainfluenza Virus Infection of the Airway Epithelium: Viral Hemagglutinin-Neuraminidase Regulates Fusion Protein Activation and Modulates Infectivity , 2009, Journal of Virology.
[13] A. Moscona,et al. Fusion properties of cells persistently infected with human parainfluenza virus type 3: participation of hemagglutinin-neuraminidase in membrane fusion , 1991, Journal of virology.
[14] R. Lamb,et al. A dual-functional paramyxovirus F protein regulatory switch segment , 2003, The Journal of cell biology.
[15] S. Niewiesk,et al. Diversifying animal models: the use of hispid cotton rats (Sigmodon hispidus) in infectious diseases , 2002, Laboratory animals.
[16] S. Walmsley,et al. Reassessment of enfuvirtide's role in the management of HIV-1 infection , 2008, Expert opinion on pharmacotherapy.
[17] G. Loughlin,et al. The Cell Biology of Acute Childhood Respiratory Disease: Therapeutic Implications , 2006, Pediatric Clinics of North America.
[18] R. Lamb,et al. Membrane fusion machines of paramyxoviruses: capture of intermediates of fusion , 2001, The EMBO journal.
[19] K. Chua,et al. Treatment of acute Nipah encephalitis with ribavirin , 2001, Annals of neurology.
[20] L. M. Palermo,et al. Fusion Promotion by a Paramyxovirus Hemagglutinin-Neuraminidase Protein: pH Modulation of Receptor Avidity of Binding Sites I and II , 2007, Journal of Virology.
[21] J. Schneider-Schaulies,et al. Measles virus infection of the CNS: human disease, animal models, and approaches to therapy , 2010, Medical Microbiology and Immunology.
[22] W. Bellini,et al. Molecular characterization of Nipah virus, a newly emergent paramyxovirus. , 2000, Virology.
[23] P. Collins,et al. Respiratory Syncytial Virus Infection of Human Airway Epithelial Cells Is Polarized, Specific to Ciliated Cells, and without Obvious Cytopathology , 2002, Journal of Virology.
[24] Oscar A. Negrete,et al. EphrinB2 is the entry receptor for Nipah virus, an emergent deadly paramyxovirus , 2005, Nature.
[25] A. Gould,et al. A morbillivirus that caused fatal disease in horses and humans. , 1995, Science.
[26] I. Wilson,et al. The influenza hemagglutinin precursor as an acid‐sensitive probe of the biosynthetic pathway. , 1987, The EMBO journal.
[27] G. Kellogg,et al. Molecular Determinants of Antiviral Potency of Paramyxovirus Entry Inhibitors , 2007, Journal of Virology.
[28] P. Collins,et al. Infection of Ciliated Cells by Human Parainfluenza Virus Type 3 in an In Vitro Model of Human Airway Epithelium , 2005, Journal of Virology.
[29] M. Enserink. Emerging infectious diseases. Nipah virus (or a cousin) strikes again. , 2004, Science.
[30] Randy J. Read,et al. Phaser crystallographic software , 2007, Journal of applied crystallography.
[31] J. White. The first family of cell-cell fusion. , 2007, Developmental cell.
[32] Laura M. Palermo,et al. Viral Entry Inhibitors Targeted to the Membrane Site of Action , 2010, Journal of Virology.
[33] M. Porotto,et al. Triggering of Human Parainfluenza Virus 3 Fusion Protein (F) by the Hemagglutinin-Neuraminidase (HN) Protein: an HN Mutation Diminishes the Rate of F Activation and Fusion , 2003, Journal of Virology.
[34] J. Zimmerberg,et al. The Anti-Influenza Virus Agent 4-GU-DANA (Zanamivir) Inhibits Cell Fusion Mediated by Human Parainfluenza Virus and Influenza Virus HA , 2000, Journal of Virology.
[35] K. Trueblood,et al. Correlation of Internal Torsional Motion with Overall Molecular Motion in Crystals , 1998 .
[36] V. Guillaume,et al. Nipah Virus: Vaccination and Passive Protection Studies in a Hamster Model , 2004, Journal of Virology.
[37] V S Lamzin,et al. Automated refinement of protein models. , 1993, Acta crystallographica. Section D, Biological crystallography.
[38] J. Guarner,et al. Nipah virus infection: pathology and pathogenesis of an emerging paramyxoviral zoonosis. , 2002, The American journal of pathology.
[39] W. Bellini,et al. Molecular biology of Hendra and Nipah viruses. , 2001, Microbes and infection.
[40] D. Kuritzkes,et al. Enfuvirtide Cerebrospinal Fluid (CSF) Pharmacokinetics and Potential use in Defining CSF HIV-1 Origin , 2008, Antiviral therapy.
[41] N. Tordo,et al. Experimental Infection of Squirrel Monkeys with Nipah Virus , 2010, Emerging infectious diseases.
[42] H. Field,et al. Human Hendra Virus Encephalitis Associated with Equine Outbreak, Australia, 2008 , 2010, Emerging infectious diseases.
[43] D. Paterson,et al. Fatal encephalitis due to novel paramyxovirus transmitted from horses , 1997, The Lancet.
[44] M. Fornabaio,et al. Paramyxovirus Receptor-Binding Molecules: Engagement of One Site on the Hemagglutinin-Neuraminidase Protein Modulates Activity at the Second Site , 2006, Journal of Virology.
[45] M. Enserink. Nipah Virus (or a Cousin) Strikes Again , 2004, Science.
[46] S. Spragg. Biophysical chemistry , 1979, Nature.
[47] Peter Briggs,et al. A graphical user interface to the CCP4 program suite. , 2003, Acta crystallographica. Section D, Biological crystallography.
[48] R. Buckland,et al. Inhibition of measles virus infection and fusion with peptides corresponding to the leucine zipper region of the fusion protein. , 1997, The Journal of general virology.
[49] J. Zou,et al. Improved methods for building protein models in electron density maps and the location of errors in these models. , 1991, Acta crystallographica. Section A, Foundations of crystallography.
[50] T. Kunkel. Rapid and efficient site-specific mutagenesis without phenotypic selection. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[51] M. Porotto,et al. Influence of the Human Parainfluenza Virus 3 Attachment Protein's Neuraminidase Activity on Its Capacity To Activate the Fusion Protein , 2005, Journal of Virology.
[52] C. Broder,et al. Feline Model of Acute Nipah Virus Infection and Protection with a Soluble Glycoprotein-Based Subunit Vaccine , 2006, Journal of Virology.
[53] M. Fornabaio,et al. Inhibition of Hendra Virus Fusion , 2006, Journal of Virology.
[54] P. Bates,et al. Heptad Repeat 2-Based Peptides Inhibit Avian Sarcoma and Leukosis Virus Subgroup A Infection and Identify a Fusion Intermediate , 2004, Journal of Virology.
[55] M. Porotto,et al. Kinetic Dependence of Paramyxovirus Entry Inhibition , 2009, Journal of Virology.
[56] M. Fornabaio,et al. A Second Receptor Binding Site on Human Parainfluenza Virus Type 3 Hemagglutinin-Neuraminidase Contributes to Activation of the FusionMechanism , 2007, Journal of Virology.
[57] L. Aschenbrenner,et al. A recombinant sialidase fusion protein effectively inhibits human parainfluenza viral infection in vitro and in vivo. , 2010, The Journal of infectious diseases.
[58] T. Morrison,et al. Interaction of Peptides with Sequences from the Newcastle Disease Virus Fusion Protein Heptad Repeat Regions , 1999, Journal of Virology.
[59] J. Bartlett. Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children , 2004 .
[60] V. Guillaume,et al. Antibody Prophylaxis and Therapy against Nipah Virus Infection in Hamsters , 2006, Journal of Virology.
[61] R. Lamb,et al. A core trimer of the paramyxovirus fusion protein: parallels to influenza virus hemagglutinin and HIV-1 gp41. , 1998, Virology.
[62] Vanessa R. Melanson,et al. Glycoprotein interactions in paramyxovirus fusion. , 2009, Future virology.
[63] J. Kaplan. Emerging Infectious Diseases Emerging Infectious Diseases , 1995 .
[64] R. Lamb,et al. Structural basis for paramyxovirus-mediated membrane fusion. , 1999, Molecular cell.
[65] C. Broder,et al. Development of an Acute and Highly Pathogenic Nonhuman Primate Model of Nipah Virus Infection , 2010, PloS one.
[66] E. Singer,et al. Neurologic presentations of AIDS. , 2010, Neurologic clinics.
[67] Winfried Weissenhorn,et al. Virus membrane fusion , 2007, FEBS Letters.
[68] Y. Shai,et al. A synthetic peptide corresponding to a conserved heptad repeat domain is a potent inhibitor of Sendai virus‐cell fusion: an emerging similarity with functional domains of other viruses. , 1995, The EMBO journal.
[69] P S Kim,et al. Mechanisms of viral membrane fusion and its inhibition. , 2001, Annual review of biochemistry.
[70] R. Lamb,et al. Paramyxovirus membrane fusion: Lessons from the F and HN atomic structures , 2005, Virology.
[71] S. Harrison. Viral membrane fusion , 2008, Nature Structural &Molecular Biology.
[72] P. Loth,et al. A golden hamster model for human acute Nipah virus infection. , 2003, The American journal of pathology.
[73] R. Compans,et al. Peptides corresponding to the heptad repeat sequence of human parainfluenza virus fusion protein are potent inhibitors of virus infection. , 1996, Virology.
[74] V. Guillaume,et al. Acute Hendra virus infection: Analysis of the pathogenesis and passive antibody protection in the hamster model. , 2009, Virology.
[75] D S Moss,et al. Main-chain bond lengths and bond angles in protein structures. , 1993, Journal of molecular biology.
[76] M. Whitt,et al. Simulating Henipavirus Multicycle Replication in a Screening Assay Leads to Identification of a Promising Candidate for Therapy , 2009, Journal of Virology.
[77] R. Dutch,et al. Viral entry mechanisms: the increasing diversity of paramyxovirus entry , 2009, The FEBS journal.
[78] M. Lawrence,et al. Inhibition of Parainfluenza Virus Type 3 and Newcastle Disease Virus Hemagglutinin-Neuraminidase Receptor Binding: Effect of Receptor Avidity and Steric Hindrance at the Inhibitor Binding Sites , 2004, Journal of Virology.
[79] J. K. Young,et al. Analysis of a peptide inhibitor of paramyxovirus (NDV) fusion using biological assays, NMR, and molecular modeling. , 1997, Virology.
[80] H. Field,et al. Nipah virus: a recently emergent deadly paramyxovirus. , 2000, Science.
[81] M. Root,et al. Asymmetric Deactivation of HIV-1 gp41 following Fusion Inhibitor Binding , 2009, PLoS pathogens.
[82] M. Porotto,et al. Human Parainfluenza Virus Type 3 HN-Receptor Interaction: Effect of 4-Guanidino-Neu5Ac2en on a Neuraminidase-Deficient Variant , 2001, Journal of Virology.
[83] Z. Otwinowski,et al. Processing of X-ray diffraction data collected in oscillation mode. , 1997, Methods in enzymology.
[84] Adeeba Kamarulzaman,et al. Fatal encephalitis due to Nipah virus among pig-farmers in Malaysia , 1999, The Lancet.
[85] Y H Chen,et al. Determination of the helix and beta form of proteins in aqueous solution by circular dichroism. , 1974, Biochemistry.
[86] H. Weingartl,et al. Organ- and endotheliotropism of Nipah virus infections in vivo and in vitro , 2009, Thrombosis and Haemostasis.
[87] H. Edelhoch,et al. Spectroscopic determination of tryptophan and tyrosine in proteins. , 1967, Biochemistry.
[88] D. Griffin. Emergence and re-emergence of viral diseases of the central nervous system , 2009, Progress in Neurobiology.
[89] M L Johnson,et al. Analysis of data from the analytical ultracentrifuge by nonlinear least-squares techniques. , 1981, Biophysical journal.
[90] D. Lambert,et al. Peptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[91] John P. Moore,et al. Addition of a cholesterol group to an HIV-1 peptide fusion inhibitor dramatically increases its antiviral potency , 2009, Proceedings of the National Academy of Sciences.
[92] Kathryn L. Schornberg,et al. Structures and mechanisms of viral membrane fusion proteins: multiple variations on a common theme. , 2008, Critical reviews in biochemistry and molecular biology.
[93] J. Sejvar,et al. Long‐term neurological and functional outcome in Nipah virus infection , 2007, Annals of neurology.
[94] Arthur J. Rowe,et al. Analytical ultracentrifugation in biochemistry and polymer science , 1992 .
[95] J. Bresee,et al. Nipah Virus Encephalitis Reemergence, Bangladesh , 2004, Emerging infectious diseases.
[96] J. A. Comer,et al. Nipah virus outbreak with person-to-person transmission in a district of Bangladesh, 2007 , 2010, Epidemiology and Infection.
[97] Stephen C. Blacklow,et al. A trimeric structural domain of the HIV-1 transmembrane glycoprotein , 1995, Nature Structural Biology.