CD44: A Cancer Stem Cell–Related Biomarker with Predictive Potential for Radiotherapy

CD44, a cancer stem cell (CSC)-related surface marker, correlates with local control after radiotherapy of early laryngeal cancer. For the first time, a CSC-related marker has been functionally validated for radiotherapy in patients. CD44 expression bears the potential to predict the outcome of radiotherapy by assessment of CSC density. Clin Cancer Res; 16(21); 5091–3. ©2010 AACR.

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