A rate limiting function of cdc25A for S phase entry inversely correlates with tyrosine dephosphorylation of Cdk2
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M. Roussel | D. Beach | C. Sherr | R. Ashmun | V. Sexl | J. Diehl | J Alan Diehl
[1] M. Roussel,et al. Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1). , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[2] Robert A. Weinberg,et al. Functional Inactivation of the Retinoblastoma Protein Requires Sequential Modification by at Least Two Distinct Cyclin-cdk Complexes , 1998, Molecular and Cellular Biology.
[3] S. Elledge,et al. Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. , 1997, Science.
[4] C. Peng,et al. Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. , 1997, Science.
[5] N. Rhind,et al. Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase. , 1997, Science.
[6] Anindya Dutta,et al. p21CIP1 and Cdc25A: competition between an inhibitor and an activator of cyclin-dependent kinases , 1997, Molecular and cellular biology.
[7] James M. Roberts,et al. Cyclin E-CDK2 is a regulator of p27Kip1. , 1997, Genes & development.
[8] S. Reed,et al. Cyclin E-induced S phase without activation of the pRb/E2F pathway. , 1997, Genes & development.
[9] J. Massagué,et al. Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-β in cells lacking the CDK inhibitor p15 , 1997, Nature.
[10] G. Draetta,et al. Cdc25 protein phosphatases in cell proliferation. , 1997, Biochimica et biophysica acta.
[11] F. Zindy,et al. Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway. , 1997, Genes & development.
[12] J. Massagué,et al. The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2. , 1997, Genes & development.
[13] J. Harper,et al. Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation. , 1997, Molecular biology of the cell.
[14] J. Pines,et al. Cyclin/Cdk-Dependent Initiation of DNA Replication in a Human Cell-Free System , 1997, Cell.
[15] B. Stillman,et al. Cell Cycle Control of DNA Replication , 1996, Science.
[16] S. Kornbluth,et al. Regulatory roles of cyclin dependent kinase phosphorylation in cell cycle control. , 1996, Current opinion in cell biology.
[17] D. Beach,et al. Cdc25 cell-cycle phosphatase as a target of c-myc , 1996, Nature.
[18] S. Reed,et al. Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest , 1996, Molecular and cellular biology.
[19] Xu Xu,et al. Roles of Active Site Residues and the NH-terminal Domain in the Catalysis and Substrate Binding of Human Cdc25 (*) , 1996, The Journal of Biological Chemistry.
[20] M. Loda,et al. CDC25 phosphatases as potential human oncogenes. , 1995, Science.
[21] P. Beer-Romero,et al. Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. , 1995, Science.
[22] M. Tatsuka,et al. Requirement for tyrosine phosphorylation of Cdk4 in Gl arrest induced by ultraviolet irradiation , 1995, Nature.
[23] M. Roussel,et al. Rescue of defective mitogenic signaling by D-type cyclins. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[24] James M. Roberts,et al. Inhibitors of mammalian G1 cyclin-dependent kinases. , 1995, Genes & development.
[25] R. Weinberg,et al. The retinoblastoma protein and cell cycle control , 1995, Cell.
[26] D. Beach,et al. Raf1 interaction with Cdc25 phosphatase ties mitogenic signal transduction to cell cycle activation. , 1995, Genes & development.
[27] James M. Roberts,et al. Human cyclin E, a nuclear protein essential for the G1-to-S phase transition , 1995, Molecular and cellular biology.
[28] P. Russell,et al. Cell cycle regulation of human WEE1. , 1995, The EMBO journal.
[29] David O. Morgan,et al. Principles of CDK regulation , 1995, Nature.
[30] S. Elledge,et al. Cdk inhibitors: on the threshold of checkpoints and development. , 1994, Current opinion in cell biology.
[31] M. Kirschner,et al. Mitosis in transition , 1994, Cell.
[32] C. Sherr. G1 phase progression: Cycling on cue , 1994, Cell.
[33] Paul Nurse,et al. Ordering S phase and M phase in the cell cycle , 1994, Cell.
[34] J. Massagué,et al. Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27 Kip1 ) of cyclin-dependent kinase 4 activation , 1994, Cell.
[35] D. Morgan,et al. Activation of cyclin-dependent kinase 4 (cdk4) by mouse MO15-associated kinase , 1994, Molecular and cellular biology.
[36] R. Weinberg,et al. A cyclin associated with the CDK-activating kinase MO15 , 1994, Nature.
[37] G. Peters. Stifled by inhibitions , 1994, Nature.
[38] E. Karsenti,et al. Activation of the phosphatase activity of human cdc25A by a cdk2‐cyclin E dependent phosphorylation at the G1/S transition. , 1994, The EMBO journal.
[39] David O. Morgan,et al. A novel cyclin associates with M015/CDK7 to form the CDK-activating kinase , 1994, Cell.
[40] R. Weinberg,et al. Collaboration of G1 cyclins in the functional inactivation of the retinoblastoma protein. , 1994, Genes & development.
[41] H Nojima,et al. Cdc25A is a novel phosphatase functioning early in the cell cycle. , 1994, The EMBO journal.
[42] E. Harlow,et al. Identification of G1 kinase activity for cdk6, a novel cyclin D partner , 1994, Molecular and cellular biology.
[43] S. Shurtleff,et al. D-type cyclin-dependent kinase activity in mammalian cells , 1994, Molecular and cellular biology.
[44] James M. Roberts,et al. p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest. , 1994, Genes & development.
[45] Charles J. Sherr,et al. Mammalian G1 cyclins , 1993, Cell.
[46] J. Pines,et al. Cyclins and cyclin-dependent kinases: take your partners , 1993 .
[47] David M. Livingston,et al. Functional interactions of the retinoblastoma protein with mammalian D-type cyclins , 1993, Cell.
[48] H. Piwnica-Worms,et al. Mechanisms of p34cdc2 regulation , 1993, Molecular and cellular biology.
[49] M. Ewen,et al. Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4. , 1993, Genes & development.
[50] E. Karsenti,et al. Phosphorylation and activation of human cdc25‐C by cdc2‐‐cyclin B and its involvement in the self‐amplification of MPF at mitosis. , 1993, The EMBO journal.
[51] D O Morgan,et al. Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15. , 1992, The EMBO journal.
[52] R. Weinberg,et al. Regulation of retinoblastoma protein functions by ectopic expression of human cyclins , 1992, Cell.
[53] P. Nurse,et al. Animal cell cycles and their control. , 1992, Annual review of biochemistry.
[54] S. Reed,et al. The role of p34 kinases in the G1 to S-phase transition. , 1992, Annual review of cell biology.
[55] D. Beach,et al. Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins , 1991, Cell.
[56] Marc W. Kirschner,et al. cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2 , 1991, Cell.
[57] A Nagata,et al. An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells. , 1991, The New biologist.
[58] S. Shurtleff,et al. Myc rescue of a mutant CSF-1 receptor impaired in mitogenic signalling , 1991, Nature.
[59] Richard A. Ashmun,et al. Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle , 1991, Cell.
[60] Karen Lundgren,et al. mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2 , 1991, Cell.
[61] E. Nigg,et al. Differential phosphorylation of vertebrate p34cdc2 kinase at the G1/S and G2/M transitions of the cell cycle: identification of major phosphorylation sites. , 1991, The EMBO journal.
[62] J. Bishop,et al. The MYC protein activates transcription of the alpha‐prothymosin gene. , 1991, The EMBO journal.
[63] J. Downing,et al. A point mutation at tyrosine-809 in the human colony-stimulating factor 1 receptor impairs mitogenesis without abrogating tyrosine kinase activity, association with phosphatidylinositol 3-kinase, or induction of c-fos and junB genes. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[64] K. Sadhu,et al. Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[65] H. Land,et al. A series of mammalian expression vectors and characterisation of their expression of a reporter gene in stably and transiently transfected cells. , 1990, Nucleic acids research.
[66] M. Roussel,et al. Mouse NIH 3T3 cells expressing human colony-stimulating factor 1 (CSF-1) receptors overgrow in serum-free medium containing human CSF-1 as their only growth factor. , 1989, Proceedings of the National Academy of Sciences of the United States of America.