Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer

Department of Radiology, Canary Center at Stanford for Cancer Early Detection, Stanford University School of Medicine, Palo Alto, CA 94304; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA 90095; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA 90095; Department of Urology, University of California, Los Angeles, CA 90095; Department of Biological Chemistry, University of California, Los Angeles, CA 90095; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA 90095; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA 90095; Division of Hematology and Medical Oncology, University of California, Los Angeles, CA 90095; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, 08903; Department of Medicine, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, 08901; Department of Pathology, University of California, Irvine, CA 92697; Department of Pathology and Laboratory Medicine, University of California, Los Angeles, CA 90095; Department of Internal Medicine, Brigham and Women’s Hospital, Boston, MA 02115; Brady Urological Institute, Johns Hopkins School of Medicine, Baltimore, MD 21287; Department of Pathology, Duke University School of Medicine, Durham, NC 27710; and Howard Hughes Medical Institute, University of California, Los Angeles, CA 90095