论文信息 - An integrated system for the evaluation of flow Mediated Dilation

An integrated system for the evaluation of flow Mediated Dilation

An integrated system capable of estimating either the stimulus (wall shear rate change) and the effect (diameter change) in Flow Mediated Dilation (FMD) ultrasound investigations is presented. The FMD integrated system consists of a modified ULA-OP research platform and a post-processing software. The ULA-OP provides a real-time visual feedback on the positioning of the ultrasound probe on the artery of interest. Both B-mode images and blood velocity profiles can be checked during the entire exam so that the operator continuously controls the morphology and the hemodynamics of the region of interest. In addition, ULA-OP is used to acquire the raw I/Q demodulated data. These are post-processed through a Matlab® platform to estimate the arterial diameter and the wall shear rate changes. Experimental examples are reported.

[1] V R Newey,et al. Online artery diameter measurement in ultrasound images using artificial neural networks. , 2002, Ultrasound in medicine & biology.

[2] F Beux,et al. Automatic evaluation of arterial diameter variation from vascular echographic images. , 2001, Ultrasound in medicine & biology.

[3] Marcello Demi,et al. The First Absolute Central Moment in Low-Level Image Processing , 2000, Comput. Vis. Image Underst..

[4] A. Dallai,et al. A reconfigurable and programmable FPGA-based system for nonstandard ultrasound methods , 2012, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[5] Å. Ahlgren,et al. A method for arterial diameter change measurements using ultrasonic B-mode data. , 2010, Ultrasound in medicine & biology.

[6] Marcello Demi,et al. A System for Real-Time Measurement of the Brachial Artery Diameter in B-Mode Ultrasound Images , 2007, IEEE Transactions on Medical Imaging.

[7] D. Celermajer,et al. Endothelium-dependent dilation in the systemic arteries of asymptomatic subjects relates to coronary risk factors and their interaction. , 1994, Journal of the American College of Cardiology.

[8] Piero Tortoli,et al. Simultaneous ultrasound assessment of brachial artery shear stimulus and flow-mediated dilation during reactive hyperemia. , 2011, Ultrasound in medicine & biology.