Practical Application of Computer-Aided Drug Design

Recent Successes and Continuing Limitations in Computer-Aided Drug Design, Paul S. Charifson and Irwin D. KuntzRecent Techniques and Applications in Pharmacophore Mapping, Mark G. BuresGeneration and Use of Three-Dimensional Databases for Drug Discovery, Ren?e L. DesJarlaisThree-Dimensional Quantitative Structure-ActivityRelation Analysis, A. J. Hopfinger and John S. TokarskiComputational Approaches to Chemical Libraries, David C. Spellmeyer, Jeffrey M. Blaney, and Eric MartinReceptor Preorganization for Activity and Its Role in Identifying Ligand-Binding Sites on Proteins, Brian K. ShoichetComparative Protein Modeling, Manuel C. PeitschDocking Conformationally Flexible Molecules into Protein Binding Sites, Millard H. LambertAn Introduction to De Novo Ligand Design, Mark A. MurckoRecent Advances in the Prediction of Binding Free Energy, Ajay, Mark A. Murcko, and Pieter F. W. StoutenLong-Range Electrostatic Effects, Ulrich Essmann and Thomas A. DardenMetals in Molecular Mechanics Force Fields and Simulations, Libero J. Bartolotti and Lee G. PedersenNew Vistas in Molecular Mechanics, J. Phillip Bowen and Guyan Liang