Renal Replacement Therapy For Elderly Patients with ESKD Through Shared Decision-Making

The incidence and prevalence of end-stage kidney disease (ESKD) in Korea are increasing, and ESKD constitutes a very important medical and social issue. Elderly dialysis patients have the highest risk of early mortality within 3 months after initiating dialysis, and geriatric syndromes such as aging, frailty, functional impairment, and cognitive impairment are crucial for the prognosis of elderly patients. Shared decision-making (SDM) is an approach through which clinicians and patients can achieve informed preferences, thereby yielding better clinical outcomes and quality of life. Through SDM-based, close consultation among patients, families, and healthcare providers, an ESKD Life-Plan for elderly patients should be established. A multidisciplinary approach led by nephrologists can help them to provide proper vascular access for dialysis at the right time, with the right evidence, and to the right patient. Strategies that can improve peritoneal dialysis in elderly patients include assisted peritoneal dialysis, homecare support programs, and automated peritoneal dialysis. In order to enhance the role of kidney transplantation in elderly patients with ESKD, it is necessary to accurately identify patients’ clinical conditions before transplantation and to perform active rehabilitation activities and postoperative management to promote recovery after transplantation. With the aging population and the increase in ESKD in the elderly, clinicians must identify factors affecting the mortality and quality of life of elderly dialysis patients.

[1]  J. V. van Delden,et al.  Asking the right questions: towards a person-centered conception of shared decision-making regarding treatment of advanced chronic kidney disease in older patients , 2022, BMC Medical Ethics.

[2]  H. Choong,et al.  Outcomes of arteriovenous fistula in elderly patients on maintenance haemodialysis , 2021, International Urology and Nephrology.

[3]  Sung Gyun Kim,et al.  A Korean perspective on the 2019 Kidney Disease Outcomes Quality Initiative guidelines for vascular access: what has changed and what should be changed in practice? , 2021, Kidney research and clinical practice.

[4]  S. H. Kim,et al.  Trends in epidemiologic characteristics of end-stage renal disease from 2019 Korean Renal Data System (KORDS) , 2021, Kidney research and clinical practice.

[5]  G. Wong,et al.  Factors Influencing Long-Term Patient and Allograft Outcomes in Elderly Kidney Transplant Recipients , 2020, Kidney international reports.

[6]  Sungjin Chung,et al.  Nephrologists' Perspectives on Decision Making About Life-Sustaining Treatment and Palliative Care at End of Life: A Questionnaire Survey in Korea. , 2020, Journal of Palliative Medicine.

[7]  B. Lau,et al.  Arteriovenous Fistula Placement, Maturation, and Patency Loss in Older Patients Initiating Hemodialysis. , 2020, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[8]  M. Chan,et al.  Perspectives in Individualizing Solutions for Dialysis Access. , 2020, Advances in chronic kidney disease.

[9]  B. Astor,et al.  KDOQI Clinical Practice Guideline for Vascular Access: 2019 Update. , 2020, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[10]  J. D. de Fijter,et al.  Transplanting the Elderly: Mandatory Age- and Minimal Histocompatibility Matching , 2020, Frontiers in Immunology.

[11]  V. Pettilä,et al.  Burden of acute kidney injury and 90-day mortality in critically ill patients , 2019, BMC Nephrology.

[12]  Chul-woo Yang,et al.  Early dialysis initiation does not improve clinical outcomes in elderly end-stage renal disease patients: A multicenter prospective cohort study , 2017, PloS one.

[13]  C. Ahn,et al.  Rehabilitation of Transplantee and Transplant Games , 2017 .

[14]  A. Kliger,et al.  Peritoneal or hemodialysis for the frail elderly patient, the choice of 2 evils? , 2017, Kidney international.

[15]  Rachael C. Walker,et al.  A Syllabus for Teaching Peritoneal Dialysis to Patients and Caregivers , 2016, Peritoneal Dialysis International.

[16]  K. Budde,et al.  Need for optimized immunosuppression in elderly kidney transplant recipients. , 2015, Transplantation reviews.

[17]  Hyunsuk Kim,et al.  Elderly Peritoneal Dialysis Compared with Elderly Hemodialysis Patients and Younger Peritoneal Dialysis Patients: Competing Risk Analysis of a Korean Prospective Cohort Study , 2015, PloS one.

[18]  B. Altun,et al.  Evaluation of Sarcopenia in Renal Transplant Recipients , 2014, Nephro-urology monthly.

[19]  L. Wong,et al.  Urgent-start peritoneal dialysis: a chance for a new beginning. , 2014, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[20]  K. Polkinghorne,et al.  Elderly patients with CKD—dilemmas in dialysis therapy and vascular access , 2014, Nature Reviews Nephrology.

[21]  R. Thomson,et al.  Shared Decision Making: A Model for Clinical Practice , 2012, Journal of General Internal Medicine.

[22]  D. Bolignano,et al.  Dialysis and the Elderly: An Underestimated Problem , 2008, Kidney and Blood Pressure Research.

[23]  E. Brown,et al.  Peritoneal dialysis for older people: overcoming the barriers. , 2008, Kidney international. Supplement.

[24]  M. Lewandowska,et al.  Need for rehabilitation in renal replacement therapy involving allogeneic kidney transplantation. , 2007, Transplantation proceedings.

[25]  A. Kiss,et al.  Home care assistance and the utilization of peritoneal dialysis. , 2007, Kidney international.