Genome-wide RNAi Screening Identifies Protein Modules Required for 40S Subunit Synthesis in Human Cells.

[1]  G. Thomas,et al.  A liaison between mTOR signaling, ribosome biogenesis and cancer. , 2015, Biochimica et biophysica acta.

[2]  D. Tollervey,et al.  Cotranscriptional events in eukaryotic ribosome synthesis , 2015, Wiley interdisciplinary reviews. RNA.

[3]  T. Mayer,et al.  Pre-anaphase chromosome oscillations are regulated by the antagonistic activities of Cdk1 and PP1 on Kif18A , 2014, Nature Communications.

[4]  S. Baserga,et al.  Human diseases of the SSU processome. , 2014, Biochimica et biophysica acta.

[5]  U. Kutay,et al.  CK1&dgr; and CK1&egr; are components of human 40S subunit precursors required for cytoplasmic 40S maturation , 2014, Journal of Cell Science.

[6]  Michael N. Hall,et al.  Making new contacts: the mTOR network in metabolism and signalling crosstalk , 2014, Nature Reviews Molecular Cell Biology.

[7]  A. Nag,et al.  CUL4A ubiquitin ligase: a promising drug target for cancer and other human diseases , 2014, Open Biology.

[8]  J. Woolford,et al.  Ribosome Biogenesis in the Yeast Saccharomyces cerevisiae , 2013, Genetics.

[9]  E. Hurt,et al.  Eukaryotic ribosome biogenesis at a glance , 2013, Journal of Cell Science.

[10]  P. Swanson,et al.  VprBP (DCAF1): a promiscuous substrate recognition subunit that incorporates into both RING-family CRL4 and HECT-family EDD/UBR5 E3 ubiquitin ligases , 2013, BMC Molecular Biology.

[11]  L. Tafforeau,et al.  The complexity of human ribosome biogenesis revealed by systematic nucleolar screening of Pre-rRNA processing factors. , 2013, Molecular cell.

[12]  R. Pearson,et al.  Dysregulation of the basal RNA polymerase transcription apparatus in cancer , 2013, Nature Reviews Cancer.

[13]  R. Pearson,et al.  Dysregulation of RNA polymerase I transcription during disease. , 2013, Biochimica et biophysica acta.

[14]  G. Thomas,et al.  Growth control and ribosomopathies. , 2013, Current opinion in genetics & development.

[15]  Damian Szklarczyk,et al.  STRING v9.1: protein-protein interaction networks, with increased coverage and integration , 2012, Nucleic Acids Res..

[16]  D. Sabatini,et al.  mTOR Signaling in Growth Control and Disease , 2012, Cell.

[17]  Matthias Mann,et al.  Analysis of High Accuracy, Quantitative Proteomics Data in the MaxQB Database , 2012, Molecular & Cellular Proteomics.

[18]  Martin Kircher,et al.  Deep proteome and transcriptome mapping of a human cancer cell line , 2011, Molecular systems biology.

[19]  M. V. Vander Heiden,et al.  Aerobic glycolysis: meeting the metabolic requirements of cell proliferation. , 2011, Annual review of cell and developmental biology.

[20]  C. Stumpf,et al.  The cancerous translation apparatus. , 2011, Current opinion in genetics & development.

[21]  Jaak Vilo,et al.  g:Profiler—a web server for functional interpretation of gene lists (2011 update) , 2011, Nucleic Acids Res..

[22]  S. Baserga,et al.  The small subunit processome in ribosome biogenesis—progress and prospects , 2011, Wiley interdisciplinary reviews. RNA.

[23]  U. Kutay,et al.  Tandem affinity purification combined with inducible shRNA expression as a tool to study the maturation of macromolecular assemblies. , 2011, RNA.

[24]  Peter Horvath,et al.  A Protein Inventory of Human Ribosome Biogenesis Reveals an Essential Function of Exportin 5 in 60S Subunit Export , 2010, PLoS biology.

[25]  C. Thompson,et al.  Glutamine addiction: a new therapeutic target in cancer. , 2010, Trends in biochemical sciences.

[26]  C. Deisenroth,et al.  Ribosome biogenesis surveillance: probing the ribosomal protein-Mdm2-p53 pathway , 2010, Oncogene.

[27]  I. Grummt,et al.  The RNA polymerase I transcription machinery: an emerging target for the treatment of cancer. , 2010, Annual review of pharmacology and toxicology.

[28]  Yue Xiong,et al.  CRL4s: the CUL4-RING E3 ubiquitin ligases. , 2009, Trends in biochemical sciences.

[29]  Ulrike Kutay,et al.  Distinct cytoplasmic maturation steps of 40S ribosomal subunit precursors require hRio2 , 2009, The Journal of cell biology.

[30]  Peter Gregor,et al.  NOPdb: Nucleolar Proteome Database—2008 update , 2008, Nucleic Acids Res..

[31]  I. Grummt,et al.  Proteasomal ATPases are associated with rDNA: the ubiquitin proteasome system plays a direct role in RNA polymerase I transcription. , 2008, Biochimica et biophysica acta.

[32]  J. Soudet,et al.  The post-transcriptional steps of eukaryotic ribosome biogenesis , 2008, Cellular and Molecular Life Sciences.

[33]  S. Mowbray,et al.  Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design. , 2008, Journal of molecular biology.

[34]  R. König,et al.  A probability-based approach for the analysis of large-scale RNAi screens , 2007, Nature Methods.

[35]  Nicola Zamboni,et al.  Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells , 2007, The Journal of cell biology.

[36]  Pengbo Zhou,et al.  DCAFs, the missing link of the CUL4-DDB1 ubiquitin ligase. , 2007, Molecular cell.

[37]  Matthias Mann,et al.  Analysis of Nucleolar Protein Dynamics Reveals the Nuclear Degradation of Ribosomal Proteins , 2007, Current Biology.

[38]  Anne E Carpenter,et al.  CellProfiler: image analysis software for identifying and quantifying cell phenotypes , 2006, Genome Biology.

[39]  J. Steitz,et al.  A spliceosomal intron binding protein, IBP160, links position-dependent assembly of intron-encoded box C/D snoRNP to pre-mRNA splicing. , 2006, Molecular cell.

[40]  Tom Misteli,et al.  Potential Roles for Ubiquitin and the Proteasome during Ribosome Biogenesis , 2006, Molecular and Cellular Biology.

[41]  Matthias Mann,et al.  NOPdb: Nucleolar Proteome Database , 2005, Nucleic Acids Res..

[42]  A. Toutain,et al.  Congenital glutamine deficiency with glutamine synthetase mutations. , 2005, The New England journal of medicine.

[43]  Toshihide Nishimura,et al.  Large‐scale analysis of the human ubiquitin‐related proteome , 2005, Proteomics.

[44]  Valérie Choesmel,et al.  Nuclear export and cytoplasmic processing of precursors to the 40S ribosomal subunits in mammalian cells , 2005, The EMBO journal.

[45]  Anthony K. L. Leung,et al.  Nucleolar proteome dynamics , 2005, Nature.

[46]  Raymond J. Deshaies,et al.  Function and regulation of cullin–RING ubiquitin ligases , 2005, Nature Reviews Molecular Cell Biology.

[47]  G. Pruijn,et al.  Role of Pre-rRNA Base Pairing and 80S Complex Formation in Subnucleolar Localization of the U3 snoRNP , 2004, Molecular and Cellular Biology.

[48]  Steven P Gygi,et al.  A proteomics approach to understanding protein ubiquitination , 2003, Nature Biotechnology.

[49]  P. Gleizes,et al.  Sequential Protein Association with Nascent 60S Ribosomal Particles , 2003, Molecular and Cellular Biology.

[50]  U. Kutay,et al.  Biogenesis and nuclear export of ribosomal subunits in higher eukaryotes depend on the CRM1 export pathway , 2003, Journal of Cell Science.

[51]  Arlen W. Johnson,et al.  Coordinated nuclear export of 60S ribosomal subunits and NMD3 in vertebrates , 2003, The EMBO journal.

[52]  Ed Hurt,et al.  Pre-ribosomes on the road from the nucleolus to the cytoplasm. , 2003, Trends in cell biology.

[53]  J. Warner,et al.  The economics of ribosome biosynthesis in yeast. , 1999, Trends in biochemical sciences.

[54]  Thomas D. Y. Chung,et al.  A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays , 1999, Journal of biomolecular screening.

[55]  R. Planta,et al.  Ribosome biogenesis in yeast. , 1991, Progress in nucleic acid research and molecular biology.