Accelerated focused ultrasound imaging

One of the most basic trade-offs in ultrasound imaging involves frame rate, depth, and number of lines. Achieving good spatial resolution and coverage requires a large number of lines, leading to decreases in frame rate. An even more serious imaging challenge occurs with imaging modes involving spatial compounding and 3-D/4-D imaging, which are severely limited by the slow speed of sound in tissue. The present work can overcome these traditional limitations, making ultrasound imaging many-fold faster. By emitting several beams at once, and by separating the resulting overlapped signals through spatial and temporal processing, spatial resolution and/or coverage can be increased by many-fold while leaving frame rates unaffected. The proposed approach can also be extended to imaging strategies that do not involve transmit beamforming, such as synthetic aperture imaging. Simulated and experimental results are presented where imaging speed is improved by up to 32-fold, with little impact on image quality. Object complexity has little impact on the method's performance, and data from biological systems can readily be handled. The present work may open the door to novel multiplexed and/or multidimensional protocols considered impractical today.

[1]  W.F. Walker,et al.  The application of k-space in pulse echo ultrasound , 1998, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[2]  E.S. Ebbini,et al.  A new coded-excitation ultrasound imaging system. I. Basic principles , 1996, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[3]  M. Fink,et al.  Coherent plane-wave compounding for very high frame rate ultrasonography and transient elastography , 2009, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[4]  Jørgen Arendt Jensen,et al.  Synthetic aperture ultrasound imaging. , 2006, Ultrasonics.

[5]  Dana H. Brooks,et al.  A tour of accelerated parallel MR imaging from a linear systems perspective , 2005 .

[6]  Bruno Madore,et al.  Extension of the UNFOLD method to include free breathing , 2006, Magnetic resonance in medicine.

[7]  Marc D Weinshenker,et al.  Explososcan: a parallel processing technique for high speed ultrasound imaging with linear phased arrays. , 1984 .

[8]  T. D. Mast,et al.  A k-space method for large-scale models of wave propagation in tissue , 2001, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[9]  Bruno Madore,et al.  Using UNFOLD to remove artifacts in parallel imaging and in partial‐Fourier imaging , 2002, Magnetic resonance in medicine.

[10]  Jules S. Jaffe Multibeam imaging using spatially variant insonification , 1989, Sixth Multidimensional Signal Processing Workshop,.

[11]  P. Boesiger,et al.  SENSE: Sensitivity encoding for fast MRI , 1999, Magnetic resonance in medicine.

[12]  N J Pelc,et al.  Unaliasing by Fourier‐encoding the overlaps using the temporal dimension (UNFOLD), applied to cardiac imaging and fMRI , 1999, Magnetic resonance in medicine.

[13]  F. Gran,et al.  Spatial encoding using a code division technique for fast ultrasound imaging , 2008, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control.

[14]  M. O'Donnell,et al.  Synthetic aperture imaging for small scale systems , 1995, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[15]  Francis A Duck,et al.  Medical and non-medical protection standards for ultrasound and infrasound. , 2007, Progress in biophysics and molecular biology.

[16]  Jørgen A Jensen,et al.  Space-time encoding for high frame rate ultrasound imaging. , 2002, Ultrasonics.

[17]  Orkun Hasekioglu,et al.  Ultrasound imaging based on multiple beamforming with coded excitation , 1997, Signal Process..

[18]  G. S. Kino,et al.  Real Time Synthetic Aperture Imaging System , 1980 .

[19]  F. Gran,et al.  Frequency division transmission imaging and synthetic aperture reconstruction , 2006, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[20]  Misha Elena Kilmer,et al.  Fast regularized reconstruction of non-uniformly subsampled parallel MRI data , 2006, 3rd IEEE International Symposium on Biomedical Imaging: Nano to Macro, 2006..

[21]  Fredrik Gran,et al.  Directional velocity estimation using a spatio-temporal encoding technique based on frequency division for synthetic transmit aperture ultrasound , 2006, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[22]  Francis A Duck,et al.  Acoustic Output Upper Limits Proposition , 2002, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[23]  K. Kwong,et al.  Parallel imaging reconstruction using automatic regularization , 2004, Magnetic resonance in medicine.

[24]  Peter Boesiger,et al.  2D sense for faster 3D MRI , 2002, Magnetic Resonance Materials in Physics, Biology and Medicine.

[25]  Jeffrey Tsao,et al.  On the UNFOLD method , 2002, Magnetic resonance in medicine.

[26]  G. R. Bredthauer,et al.  Array design for ultrasound imaging with simultaneous beams , 2002, Proceedings IEEE International Symposium on Biomedical Imaging.

[27]  Clement,et al.  Field characterization of therapeutic ultrasound phased arrays through forward and backward planar projection , 2000, The Journal of the Acoustical Society of America.

[28]  Bruno Madore,et al.  UNFOLD‐SENSE: A parallel MRI method with self‐calibration and artifact suppression , 2004, Magnetic resonance in medicine.

[29]  M. Fink,et al.  Assessment of the mechanical properties of the musculoskeletal system using 2-D and 3-D very high frame rate ultrasound , 2008, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[30]  W. Manning,et al.  Simultaneous acquisition of spatial harmonics (SMASH): Fast imaging with radiofrequency coil arrays , 1997, Magnetic resonance in medicine.

[31]  F H Epstein,et al.  Adaptive sensitivity encoding incorporating temporal filtering (TSENSE) † , 2001, Magnetic resonance in medicine.

[32]  J. G. Abbott,et al.  Rationale and derivation of MI and TI--a review. , 1999, Ultrasound in medicine & biology.

[33]  송태경,et al.  Ultrasound imaging system and method based on simultaneous multiple transmit-focusing using the weighted orthogonal chirp signals , 2001 .