Computer-aided diagnosis in chest imaging: how to improve performance and avoid reinventing the wheel

Computer-aided diagnosis (CAD) is a rapidly expanding area of medical image analysis that aims to help clinicians in making a proper diagnosis by, for example, detecting abnormalities, classifying and diagnosing these, and quantifying the spread of disease. The largest efforts in CAD, both commercially and academically, have been aimed at mammography, but chest imaging is the second major area.