Development of recombinant adeno-associated virus vectors carrying small interfering RNA (shHec1)-mediated depletion of kinetochore Hec1 protein in tumor cells

[1]  M. Kay,et al.  The 37/67-Kilodalton Laminin Receptor Is a Receptor for Adeno-Associated Virus Serotypes 8, 2, 3, and 9 , 2006, Journal of Virology.

[2]  Z. Dai,et al.  Down-regulation of survivin expression by small interfering RNA induces pancreatic cancer cell apoptosis and enhances its radiosensitivity. , 2006, World journal of gastroenterology.

[3]  M. Hallek,et al.  Adeno‐associated virus serotypes 1 to 5 mediated tumor cell directed gene transfer and improvement of transduction efficiency , 2005, The journal of gene medicine.

[4]  J. Lachowicz,et al.  RNA interference targeting of A1 receptor-overexpressing breast carcinoma cells leads to diminished rates of cell proliferation and induction of apoptosis , 2005, Cancer biology & therapy.

[5]  Michael J. Emanuele,et al.  Measuring the stoichiometry and physical interactions between components elucidates the architecture of the vertebrate kinetochore. , 2005, Molecular biology of the cell.

[6]  Andrea Musacchio,et al.  Architecture of the Human Ndc80-Hec1 Complex, a Critical Constituent of the Outer Kinetochore* , 2005, Journal of Biological Chemistry.

[7]  H. Paulson,et al.  RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[8]  Nihal Ahmad,et al.  Silencing of polo‐like kinase (Plk) 1 via siRNA causes induction of apoptosis and impairment of mitosis machinery in human prostate cancer cells: implications for the treatment of prostate cancer , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[9]  A. Desai,et al.  Kinetochore-spindle microtubule interactions during mitosis. , 2005, Current opinion in cell biology.

[10]  R. Samulski,et al.  Integration of adeno-associated virus (AAV) and recombinant AAV vectors. , 2004, Annual review of genetics.

[11]  E. Salmon,et al.  Hec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites. , 2004, Molecular biology of the cell.

[12]  M. Wirth,et al.  siRNA-mediated down-regulation of survivin inhibits bladder cancer cell growth. , 2004, International journal of oncology.

[13]  H. Paulson,et al.  RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia , 2004, Nature Medicine.

[14]  L. Poliseno,et al.  RNA-based drugs: from RNA interference to short interfering RNAs. , 2004, Current pharmaceutical biotechnology.

[15]  J. Rossi,et al.  Recent applications of RNAi in mammalian systems. , 2004, Current pharmaceutical biotechnology.

[16]  O. Heidenreich Oncogene suppression by small interfering RNAs. , 2004, Current pharmaceutical biotechnology.

[17]  A. Borkhardt,et al.  Silencing of disease-related genes by small interfering RNAs. , 2004, Current molecular medicine.

[18]  E. Nigg,et al.  Kinetochore localization and microtubule interaction of the human spindle checkpoint kinase Mps1 , 2004, Chromosoma.

[19]  Hiroyuki Miyoshi,et al.  Optimization of an siRNA‐expression system with an improved hairpin and its significant suppressive effects in mammalian cells , 2004, The journal of gene medicine.

[20]  Linda Yang,et al.  The DNA minor groove binding agents Hoechst 33258 and 33342 enhance recombinant adeno-associated virus (rAAV) transgene expression. , 2004, The journal of gene medicine.

[21]  Hongtao Yu,et al.  Identification of Two Novel Components of the Human NDC80 Kinetochore Complex*[boxs] , 2004, Journal of Biological Chemistry.

[22]  J. Shabanowitz,et al.  The Vertebrate Ndc80 Complex Contains Spc24 and Spc25 Homologs, which Are Required to Establish and Maintain Kinetochore-Microtubule Attachment , 2004, Current Biology.

[23]  E. Salmon,et al.  Nuf2 and Hec1 Are Required for Retention of the Checkpoint Proteins Mad1 and Mad2 to Kinetochores , 2003, Current Biology.

[24]  K. Sakamoto,et al.  RNA interference and human disease. , 2003, Molecular genetics and metabolism.

[25]  P. Chaudhary,et al.  Use of adeno-associated viral vector for delivery of small interfering RNA , 2003, Oncogene.

[26]  C. Vite,et al.  Intraventricular Brain Injection of Adeno-Associated Virus Type 1 (AAV1) in Neonatal Mice Results in Complementary Patterns of Neuronal Transduction to AAV2 and Total Long-Term Correction of Storage Lesions in the Brains of β-Glucuronidase-Deficient Mice , 2003, Journal of Virology.

[27]  Xiaoqi Liu,et al.  Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[28]  Patrick J. Paddison,et al.  An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo , 2003, Nature Genetics.

[29]  D. Riley,et al.  Phosphorylation of the Mitotic Regulator Protein Hec1 by Nek2 Kinase Is Essential for Faithful Chromosome Segregation* , 2002, The Journal of Biological Chemistry.

[30]  R. Kotin,et al.  Insect cells as a factory to produce adeno-associated virus type 2 vectors. , 2002, Human gene therapy.

[31]  Ali Ehsani,et al.  Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells , 2002, Nature Biotechnology.

[32]  K. Taira,et al.  U6 promoter–driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells , 2002, Nature Biotechnology.

[33]  Stacy L DeRuiter,et al.  RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[34]  W. Forrester,et al.  A DNA vector-based RNAi technology to suppress gene expression in mammalian cells , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[35]  N. Mailand,et al.  Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation , 2002, Nature Cell Biology.

[36]  R. Bernards,et al.  A System for Stable Expression of Short Interfering RNAs in Mammalian Cells , 2002, Science.

[37]  Patrick J. Paddison,et al.  Stable suppression of gene expression by RNAi in mammalian cells , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[38]  J. Chiorini,et al.  Adeno-Associated Virus Serotype 4 (AAV4) and AAV5 Both Require Sialic Acid Binding for Hemagglutination and Efficient Transduction but Differ in Sialic Acid Linkage Specificity , 2001, Journal of Virology.

[39]  T. Tuschl,et al.  Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells , 2001, Nature.

[40]  R. Samulski,et al.  Membrane-Associated Heparan Sulfate Proteoglycan Is a Receptor for Adeno-Associated Virus Type 2 Virions , 1998, Journal of Virology.

[41]  M. Izquierdo,et al.  RNA interference against Hec1 inhibits tumor growth in vivo , 2006, Gene Therapy.

[42]  A. Harel-Bellan,et al.  [RNA interference and its possible use in cancer therapy]. , 2004, Bulletin du cancer.

[43]  A. Harel-Bellan,et al.  Inhibition de l‘expression génique par l‘ARN interférence : applications dans le domaine du cancer , 2004 .

[44]  R. Samulski,et al.  AlphaVbeta5 integrin: a co-receptor for adeno-associated virus type 2 infection. , 1999, Nature medicine.

[45]  R. Samulski,et al.  αVβ5 integrin: a co-receptor for adeno-associated virus type 2 infection , 1999, Nature Medicine.