Rescuing fertility during COVID-19 infection: exploring potential pharmacological and natural therapeutic approaches for comorbidity, by focusing on NLRP3 inflammasome mechanism.

[1]  Akhilesh,et al.  Decrypting the cellular and molecular intricacies associated with COVID-19-induced chronic pain , 2022, Metabolic Brain Disease.

[2]  Shijun Zhang,et al.  The NLRP3 Inflammasome Pathway: A Review of Mechanisms and Inhibitors for the Treatment of Inflammatory Diseases , 2022, Frontiers in Aging Neuroscience.

[3]  Mohamed Hadi Mohamed Abdelhamid,et al.  An Assessment of Men Semen Alterations in SARS-CoV-2: Is Fever the Principal Concern? , 2022, Reproductive Sciences.

[4]  C. Mehedințu,et al.  The Effects of SARS-CoV-2 Infection on Female Fertility: A Review of the Literature , 2022, International journal of environmental research and public health.

[5]  D. Abramovich,et al.  SARS-CoV-2 infection negatively affects ovarian function in ART patients , 2021, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.

[6]  Libo Zhu,et al.  NLRP3 Inflammasome Activation of Mast Cells by Estrogen via the Nuclear-Initiated Signaling Pathway Contributes to the Development of Endometriosis , 2021, Frontiers in Immunology.

[7]  M. Nazari,et al.  NLRP3 inflammasome: A joint, potential therapeutic target in management of COVID-19 and fertility problems , 2021, Journal of Reproductive Immunology.

[8]  Shannon M. Malloy,et al.  THE RELATIONSHIP BETWEEN PERCEIVED STRESS DURING THE COVID-19 PANDEMIC AND MENSTRUAL CYCLES AND SYMPTOMS , 2021, Fertility and Sterility.

[9]  C. Touboul,et al.  Mild COVID-19 infection does not alter the ovarian reserve in women treated with ART , 2021, Reproductive BioMedicine Online.

[10]  M. Abdollahifar,et al.  COVID-19 disrupts the blood–testis barrier through the induction of inflammatory cytokines and disruption of junctional proteins , 2021, Inflammation Research.

[11]  M. Salehi,et al.  Combination of pioglitazone and clomiphene citrate versus clomiphene citrate alone for infertile women with the polycystic ovarian syndrome , 2021, BMC Women's Health.

[12]  Jianguo Wu,et al.  SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation , 2021, Nature Communications.

[13]  X. Ren,et al.  Investigating the impact of asymptomatic or mild SARS-CoV-2 infection on female fertility and in vitro fertilization outcomes: A retrospective cohort study , 2021, EClinicalMedicine.

[14]  A. Agarwal,et al.  The impact of COVID-19 on the male reproductive tract and fertility: A systematic review , 2021, Arab journal of urology.

[15]  Jennifer K. Blakemore,et al.  TRENDS IN FSH LEVELS AND CYCLE COMPLETION RATES IN WOMEN UNDERGOING ASSISTED REPRODUCTIVE TECHNOLOGY (ART) BEFORE AND DURING THE COVID-19 PANDEMIC , 2021, Fertility and Sterility.

[16]  Li-li Xu,et al.  The NLRP3 inflammasome and COVID-19: Activation, pathogenesis and therapeutic strategies , 2021, Cytokine & Growth Factor Reviews.

[17]  Jie Wang,et al.  Effect of COVID-19 on Male Reproductive System – A Systematic Review , 2021, Frontiers in Endocrinology.

[18]  R. Orvieto,et al.  Does COVID-19 infection influence patients’ performance during IVF-ET cycle?: an observational study , 2021, Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.

[19]  J. Pizzicannella,et al.  Antioxidant Ascorbic Acid Modulates NLRP3 Inflammasome in LPS-G Treated Oral Stem Cells through NFκB/Caspase-1/IL-1β Pathway , 2021, Antioxidants.

[20]  J. Lieberman,et al.  Gasdermin D pore structure reveals preferential release of mature interleukin-1 , 2021, Nature.

[21]  D. Wolf,et al.  Ovarian follicular function is not altered by SARS–CoV-2 infection or BNT162b2 mRNA COVID-19 vaccination , 2021, medRxiv.

[22]  Z. Mekonnen,et al.  The Impact of Vitamin D Level on COVID-19 Infection: Systematic Review and Meta-Analysis , 2021, Frontiers in Public Health.

[23]  S. Soltani,et al.  The coronavirus disease 2019 and effect on liver function: a hidden and vital interaction beyond the respiratory system , 2021, Reviews in Medical Microbiology.

[24]  Sunil Krishnan,et al.  Testicular Atrophy and Hypothalamic Pathology in COVID-19: Possibility of the Incidence of Male Infertility and HPG Axis Abnormalities , 2021, Reproductive Sciences.

[25]  G. Moore,et al.  Anomalous collapses of Nares Strait ice arches leads to enhanced export of Arctic sea ice , 2021, Nature communications.

[26]  V. Poortahmasebi,et al.  A systematic literature review on COVID-19, clinical manifestation, laboratory and radiologic features , 2021 .

[27]  Antonio J. Pérez-Pulido,et al.  Inhibition of the NLRP3 inflammasome prevents ovarian aging , 2020, Science Advances.

[28]  Yanhua Zhao,et al.  Expression of SARS-CoV-2 entry genes ACE2 and TMPRSS2 at single cell resolution in the peripartum decidua. , 2021, American journal of translational research.

[29]  Dingyu Zhang,et al.  Pathological and molecular examinations of postmortem testis biopsies reveal SARS-CoV-2 infection in the testis and spermatogenesis damage in COVID-19 patients , 2020, Cellular & molecular immunology.

[30]  Z. Yin,et al.  Controlling Cytokine Storm Is Vital in COVID-19 , 2020, Frontiers in Immunology.

[31]  P. H. Gois,et al.  Vitamin D and the NLRP3 Inflammasome , 2020, Applied Sciences.

[32]  C. Librach,et al.  A comprehensive review of the impact of COVID-19 on human reproductive biology, assisted reproduction care and pregnancy: a Canadian perspective , 2020, Journal of Ovarian Research.

[33]  Geun-Shik Lee,et al.  Riboflavin, vitamin B2, attenuates NLRP3, NLRC4, AIM2, and non-canonical inflammasomes by the inhibition of caspase-1 activity , 2020, Scientific Reports.

[34]  Songying Zhang,et al.  NLRP3 inflammasome: a new therapeutic target for high-risk reproductive disorders? , 2020, Chinese medical journal.

[35]  R. Ramasamy,et al.  Histopathology and Ultrastructural Findings of Fatal COVID-19 Infections on Testis , 2020, The world journal of men's health.

[36]  C. Wagner,et al.  Evidence Regarding Vitamin D and Risk of COVID-19 and Its Severity , 2020, Nutrients.

[37]  Xiaoguang Zhao,et al.  Zinc provides neuroprotection by regulating NLRP3 inflammasome through autophagy and ubiquitination in a spinal contusion injury model , 2020, CNS neuroscience & therapeutics.

[38]  J. P. de Rivero Vaccari,et al.  The Inflammasome in Times of COVID-19 , 2020, Frontiers in Immunology.

[39]  P. Halami,et al.  Immune-Boosting, Antioxidant and Anti-inflammatory Food Supplements Targeting Pathogenesis of COVID-19 , 2020, Frontiers in Immunology.

[40]  Zhènglì Shí,et al.  Characteristics of SARS-CoV-2 and COVID-19 , 2020, Nature Reviews Microbiology.

[41]  J. Ting,et al.  Inflammasome Assays In Vitro and in Mouse Models , 2020, Current protocols in immunology.

[42]  Liming Cheng,et al.  Analysis of sex hormone, menstruation and ovarian reserve in COVID-19 women of child-bearing age: a cross-sectional study , 2020, Reproductive BioMedicine Online.

[43]  G. Ricci,et al.  SARS-CoV-2 and the next generations: which impact on reproductive tissues? , 2020, Journal of Assisted Reproduction and Genetics.

[44]  P. Lehner,et al.  How does SARS-CoV-2 cause COVID-19? , 2020, Science.

[45]  H. Akhavan-Niaki,et al.  Emerging role of IL-6 and NLRP3 inflammasome as potential therapeutic targets to combat COVID-19: Role of lncRNAs in cytokine storm modulation , 2020, Life Sciences.

[46]  L. Gianaroli,et al.  Assisted reproduction and COVID-19: A joint statement of ASRM, ESHRE and IFFS , 2020, Fertility and Sterility.

[47]  Jun Sun.  The hypothesis that SARS-CoV-2 affects male reproductive ability by regulating autophagy , 2020, Medical Hypotheses.

[48]  J. Inal.  COVID‐19 comorbidities, associated procoagulant extracellular vesicles and venous thromboembolisms: a possible link with ethnicity? , 2020, British journal of haematology.

[49]  Zhimin Chen,et al.  Evaluation of sex‐related hormones and semen characteristics in reproductive‐aged male COVID‐19 patients , 2020, Journal of medical virology.

[50]  S. Luo,et al.  Targeting inflammation and cytokine storm in COVID-19 , 2020, Pharmacological Research.

[51]  A. T. Te Velde,et al.  Severe COVID-19: NLRP3 Inflammasome Dysregulated , 2020, Frontiers in Immunology.

[52]  Dan Liu,et al.  NLRP3 inflammasome inhibitor MCC950 attenuates primary dysmenorrhea in mice via the NF-κB/COX-2/PG pathway , 2020, Journal of Inflammation.

[53]  T. Swartz,et al.  Targeting the NLRP3 Inflammasome in Severe COVID-19 , 2020, Frontiers in Immunology.

[54]  Kharbach Youssef,et al.  Male genital damage in COVID-19 patients: Are available data relevant? , 2020 .

[55]  A. Khallouk,et al.  Male genital damage in COVID-19 patients: Are available data relevant? , 2020, Asian Journal of Urology.

[56]  COVID 19 Pandemic, Mechanism of Pathogenesis, Preventions and Possible Cures to Save Humanity: A Study , 2020, Journal of Infertility and Reproductive Biology.

[57]  P. Sebastián-León,et al.  SARS-CoV-2 infection risk assessment in the endometrium: viral infection-related gene expression across the menstrual cycle , 2020, Fertility and Sterility.

[58]  A. Iwasaki,et al.  Inflammasomes and Pyroptosis as Therapeutic Targets for COVID-19 , 2020, The Journal of Immunology.

[59]  Nehla Banu,et al.  Protective role of ACE2 and its downregulation in SARS-CoV-2 infection leading to Macrophage Activation Syndrome: Therapeutic implications , 2020, Life Sciences.

[60]  Xiang Li,et al.  Pathological Findings in the Testes of COVID-19 Patients: Clinical Implications , 2020, European Urology Focus.

[61]  Z. Blumenfeld.  The possible impact of COVID 19 on fertility and ART , 2020, Fertility and Sterility.

[62]  E. Illiano,et al.  Could COVID‐19 have an impact on male fertility? , 2020, Andrologia.

[63]  H. Sadri-Ardekani,et al.  ACE2 receptor expression in testes: implications in coronavirus disease 2019 pathogenesis , 2020, Biology of Reproduction.

[64]  A. Shah.  Novel Coronavirus-Induced NLRP3 Inflammasome Activation: A Potential Drug Target in the Treatment of COVID-19 , 2020, Frontiers in Immunology.

[65]  E. Thomas,et al.  Coronavirus disease-19 and fertility: viral host entry protein expression in male and female reproductive tissues , 2020, Fertility and Sterility.

[66]  Fang Li,et al.  Cell entry mechanisms of SARS-CoV-2 , 2020, Proceedings of the National Academy of Sciences.

[67]  M. Cooperberg,et al.  Expression of ACE2, the SARS-CoV-2 Receptor, and TMPRSS2 in Prostate Epithelial Cells , 2020, European Urology.

[68]  H. Kai,et al.  Interactions of coronaviruses with ACE2, angiotensin II, and RAS inhibitors—lessons from available evidence and insights into COVID-19 , 2020, Hypertension Research.

[69]  Philip S Li,et al.  No evidence of SARS-CoV-2 in semen of males recovering from COVID-19 , 2020, Fertility and Sterility.

[70]  C. Lindskog,et al.  The protein expression profile of ACE2 in human tissues , 2020, bioRxiv.

[71]  Y. Malik,et al.  Properties of Coronavirus and SARS-CoV-2. , 2020, The Malaysian journal of pathology.

[72]  Y. Zhang,et al.  Effect of SARS-CoV-2 infection upon male gonadal function: A single center-based study , 2020, medRxiv.

[73]  J. Lieberman,et al.  FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation , 2020, Nature Immunology.

[74]  K. Shi,et al.  Structural basis of receptor recognition by SARS-CoV-2 , 2020, Nature.

[75]  E. Holmes,et al.  The proximal origin of SARS-CoV-2 , 2020, Nature Medicine.

[76]  H. Breitinger,et al.  Viroporins and inflammasomes: A key to understand virus-induced inflammation , 2020, The International Journal of Biochemistry & Cell Biology.

[77]  G. Herrler,et al.  SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor , 2020, Cell.

[78]  Bing Han,et al.  COVID-19: Gastrointestinal Manifestations and Potential Fecal–Oral Transmission , 2020, Gastroenterology.

[79]  Yuntao Wu,et al.  Understanding SARS-CoV-2-Mediated Inflammatory Responses: From Mechanisms to Potential Therapeutic Tools , 2020, Virologica Sinica.

[80]  C. Beyer,et al.  Presence of The NLRP3 Inflammasome Components in Semen of Varicocele Patients , 2020, International journal of fertility & sterility.

[81]  Zhengpin Wang,et al.  scRNA-seq Profiling of Human Testes Reveals the Presence of the ACE2 Receptor, A Target for SARS-CoV-2 Infection in Spermatogonia, Leydig and Sertoli Cells , 2020, Cells.

[82]  B. Graham,et al.  Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation , 2020, Science.

[83]  P. Niu,et al.  Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China , 2020, Cell Host & Microbe.

[84]  Yan Zhao,et al.  Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. , 2020, JAMA.

[85]  K. Hansen,et al.  Obesity significantly alters the human sperm proteome, with potential implications for fertility , 2020, Journal of Assisted Reproduction and Genetics.

[86]  Qiang Huang,et al.  Fast assessment of human receptor-binding capability of 2019 novel coronavirus (2019-nCoV) , 2020, bioRxiv.

[87]  Kai Zhao,et al.  A pneumonia outbreak associated with a new coronavirus of probable bat origin , 2020, Nature.

[88]  Christian Drosten,et al.  The novel coronavirus 2019 (2019-nCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells , 2020, bioRxiv.

[89]  E. Holmes,et al.  Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding , 2020, The Lancet.

[90]  J. P. de Rivero Vaccari.  The Inflammasome in Reproductive Biology: A Promising Target for Novel Therapies , 2020, Frontiers in Endocrinology.

[91]  J. I. Izpisúa Belmonte,et al.  Single-Cell Transcriptomic Atlas of Primate Ovarian Aging , 2020, Cell.

[92]  H. Nouri,et al.  Elevated expression of IL-18 but not IL-1β gene is associated with NALP3 and AIM2 inflammasome in Polycystic Ovary Syndrome. , 2020, Gene.

[93]  J. Luban.  SARS-CoV-2 , 2020 .

[94]  R. Romero,et al.  Inflammasomes: Their Role in Normal and Complicated Pregnancies , 2019, The Journal of Immunology.

[95]  T. Jin,et al.  Pharmacological Inhibitors of the NLRP3 Inflammasome , 2019, Front. Immunol..

[96]  Heaji Lee,et al.  Gamma-tocopherol ameliorates hyperglycemia-induced hepatic inflammation associated with NLRP3 inflammasome in alloxan-induced diabetic mice , 2019, Nutrition research and practice.

[97]  M. Nasr-Esfahani,et al.  Evaluation of Oxidative Stress in Testis and Sperm of Rat Following Induced Varicocele. , 2019, Urology journal.

[98]  Zhaochun Liu,et al.  microRNA-520c-3p suppresses NLRP3 inflammasome activation and inflammatory cascade in preeclampsia by downregulating NLRP3 , 2019, Inflammation Research.

[99]  C. Day,et al.  MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition , 2019, Nature Chemical Biology.

[100]  A. Ohkuchi,et al.  Olive Leaf Extract (OleaVita) Suppresses Inflammatory Cytokine Production and NLRP3 Inflammasomes in Human Placenta , 2019, Nutrients.

[101]  Takeshi Ichinohe,et al.  Severe Acute Respiratory Syndrome Coronavirus Viroporin 3a Activates the NLRP3 Inflammasome , 2019, Front. Microbiol..

[102]  L. Navar,et al.  Inflammation as a Regulator of the Renin-Angiotensin System and Blood Pressure , 2018, Current Hypertension Reports.

[103]  R. Romero,et al.  Inflammasome activation during spontaneous preterm labor with intra‐amniotic infection or sterile intra‐amniotic inflammation , 2018, American journal of reproductive immunology.

[104]  M. Poutanen,et al.  NLRP3 in somatic non-immune cells of rodent and primate testes. , 2018, Reproduction.

[105]  L. Walenta,et al.  Mechanisms of sterile inflammation in the testis , 2018 .

[106]  V. Papadopoulos,et al.  Leydig cells: formation, function, and regulation† , 2018, Biology of Reproduction.

[107]  R. Romero,et al.  A Role for the Inflammasome in Spontaneous Labor at Term , 2018, American journal of reproductive immunology.

[108]  S. Hosseini,et al.  Lipid Peroxidation and Its Role in the Expression of NLRP1a and NLRP3 Genes in Testicular Tissue of Male Rats: A Model of Spinal Cord Injury , 2018, Iranian biomedical journal.

[109]  Jelena S. Bezbradica,et al.  Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity , 2018, The Journal of experimental medicine.

[110]  A. Zendedel,et al.  Resveratrol decreases apoptosis and NLRP3 complex expressions in experimental varicocele rat model , 2018, Iranian journal of basic medical sciences.

[111]  B. Ryffel,et al.  AMP-Activated Protein Kinase Regulation of the NLRP3 Inflammasome during Aging , 2018, Trends in Endocrinology & Metabolism.

[112]  Liming Lu,et al.  Obesity or Overweight, a Chronic Inflammatory Status in Male Reproductive System, Leads to Mice and Human Subfertility , 2018, Front. Physiol..

[113]  Shih-Chieh Lee,et al.  Anti-inflammatory effect of cinnamaldehyde and linalool from the leaf essential oil of Cinnamomum osmophloeum Kanehira in endotoxin-induced mice , 2017, Journal of food and drug analysis.

[114]  L. Rink,et al.  Zinc as a Gatekeeper of Immune Function , 2017, Nutrients.

[115]  C. Thornton,et al.  Expression and function of NOD-like receptors by human term gestation-associated tissues. , 2017, Placenta.

[116]  L. Rink,et al.  Zinc Signals and Immunity , 2017, International journal of molecular sciences.

[117]  J. Araujo,et al.  Increased expression of NLRP3 inflammasome in placentas from pregnant women with severe preeclampsia. , 2017, Journal of reproductive immunology.

[118]  G. Wagner,et al.  Embryo implantation evolved from an ancestral inflammatory attachment reaction , 2017, Proceedings of the National Academy of Sciences.

[119]  Ming-Hua Yang,et al.  Pioglitazone ameliorates glomerular NLRP3 inflammasome activation in apolipoprotein E knockout mice with diabetes mellitus , 2017, PloS one.

[120]  D. Greaves,et al.  The PYRIN domain-only protein POP2 inhibits inflammasome priming and activation , 2017, Nature Communications.

[121]  R. Romero,et al.  A Role for the Inflammasome in Spontaneous Labor at Term with Acute Histologic Chorioamnionitis , 2017, Reproductive Sciences.

[122]  R. Romero,et al.  Inflammasome assembly in the chorioamniotic membranes during spontaneous labor at term , 2017, American journal of reproductive immunology.

[123]  Haitao Guo,et al.  NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes , 2017, The Journal of experimental medicine.

[124]  A. Pontecorvi,et al.  Prednisone treatment in infertile patients with oligozoospermia and accessory gland inflammatory alterations , 2017, Andrology.

[125]  C. Zeiss,et al.  β-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares. , 2017, Cell reports.

[126]  A. Oliviero,et al.  Early spermatogenesis changes in traumatic complete spinal cord-injured adult patients , 2017, Spinal Cord.

[127]  M. Nouri,et al.  Expression of mRNA and protein of IL-18 and its receptor in human follicular granulosa cells , 2017, Journal of Endocrinological Investigation.

[128]  Wei Zhang,et al.  Nicotinic acid inhibits NLRP3 inflammasome activation via SIRT1 in vascular endothelial cells. , 2016, International immunopharmacology.

[129]  H. Imura,et al.  Vitamin B6 Prevents IL-1β Protein Production by Inhibiting NLRP3 Inflammasome Activation* , 2016, The Journal of Biological Chemistry.

[130]  Myung-Shik Lee,et al.  Mitochondria and the NLRP3 inflammasome: physiological and pathological relevance , 2016, Archives of pharmacal research.

[131]  Fang Zhang,et al.  The caspase-1 inhibitor AC-YVAD-CMK attenuates acute gastric injury in mice: involvement of silencing NLRP3 inflammasome activities , 2016, Scientific Reports.

[132]  A. Bitto,et al.  ROS-Mediated NLRP3 Inflammasome Activation in Brain, Heart, Kidney, and Testis Ischemia/Reperfusion Injury , 2016, Oxidative medicine and cellular longevity.

[133]  Jian Zhang,et al.  The role of Resveratrol-induced mitophagy/autophagy in peritoneal mesothelial cells inflammatory injury via NLRP3 inflammasome activation triggered by mitochondrial ROS. , 2016, Experimental cell research.

[134]  A. Bitto,et al.  NLRP3 Inflammasome Involvement in the Organ Damage and Impaired Spermatogenesis Induced by Testicular Ischemia and Reperfusion in Mice , 2015, The Journal of Pharmacology and Experimental Therapeutics.

[135]  R. Khan,et al.  A clear and present danger: inflammasomes DAMPing down disorders of pregnancy. , 2015, Human reproduction update.

[136]  R. Romero,et al.  Clinical chorioamnionitis at term I: microbiology of the amniotic cavity using cultivation and molecular techniques , 2015, Journal of perinatal medicine.

[137]  Fang Li,et al.  Receptor Recognition Mechanisms of Coronaviruses: a Decade of Structural Studies , 2014, Journal of Virology.

[138]  J. P. de Rivero Vaccari,et al.  Neutralization of ASC improves sperm motility in men with spinal cord injury. , 2014, Human reproduction.

[139]  C. Bing,et al.  Interleukin-1β mediates macrophage-induced impairment of insulin signaling in human primary adipocytes , 2014, American journal of physiology. Endocrinology and metabolism.

[140]  R. Romero,et al.  A Novel Molecular Microbiologic Technique for the Rapid Diagnosis of Microbial Invasion of the Amniotic Cavity and Intra‐Amniotic Infection in Preterm Labor with Intact Membranes , 2014, American journal of reproductive immunology.

[141]  D. Sinclair,et al.  Germline energetics, aging, and female infertility. , 2013, Cell metabolism.

[142]  S. Crovella,et al.  Bacterial LPS Differently Modulates Inflammasome Gene Expression and IL-1β Secretion in Trophoblast Cells, Decidual Stromal Cells, and Decidual Endothelial Cells , 2013, Reproductive Sciences.

[143]  L. Cuisset,et al.  Muckle-Wells syndrome and male hypofertility: a case series. , 2012, Seminars in arthritis and rheumatism.

[144]  B. Ergur,et al.  The Effects of α-Lipoic Acid against Testicular Ischemia-Reperfusion Injury in Rats , 2012, TheScientificWorldJournal.

[145]  Luis Carrasco,et al.  Viroporins: structure and biological functions , 2012, Nature Reviews Microbiology.

[146]  M. Moore,et al.  Spinal Cord Injury Causes Sustained Disruption of the Blood-Testis Barrier in the Rat , 2011, PloS one.

[147]  G. Remuzzi,et al.  Angiotensin II revisited: new roles in inflammation, immunology and aging , 2010, EMBO molecular medicine.

[148]  F. Reis,et al.  Angiotensin (1–7) and its receptor Mas are expressed in the human testis: implications for male infertility , 2010, Journal of Molecular Histology.

[149]  E. Alnemri,et al.  Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome* , 2010, The Journal of Biological Chemistry.

[150]  J. Tschopp,et al.  The Inflammasomes , 2010, Cell.

[151]  V. Dixit,et al.  Glyburide inhibits the Cryopyrin/Nalp3 inflammasome , 2009, The Journal of cell biology.

[152]  H. Hammad,et al.  Cutting Edge: Alum Adjuvant Stimulates Inflammatory Dendritic Cells through Activation of the NALP3 Inflammasome , 2008, The Journal of Immunology.

[153]  P. Gonçalves,et al.  The role of angiotensin II in the early stages of bovine ovulation. , 2007, Reproduction.

[154]  F. Martinon,et al.  Inflammasome Components NALP 1 and 3 Show Distinct but Separate Expression Profiles in Human Tissues Suggesting a Site-specific Role in the Inflammatory Response , 2007, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[155]  F. Martinon,et al.  A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses , 2007, Nature Immunology.

[156]  H. Forman,et al.  ATP Activates a Reactive Oxygen Species-dependent Oxidative Stress Response and Secretion of Proinflammatory Cytokines in Macrophages* , 2007, Journal of Biological Chemistry.

[157]  M. Fraczek,et al.  Inflammatory mediators exert toxic effects of oxidative stress on human spermatozoa. , 2006, Journal of andrology.

[158]  P. Gonçalves,et al.  Effect of angiotensin II with follicle cells and insulin-like growth factor-I or insulin on bovine oocyte maturation and embryo development. , 2006, Theriogenology.

[159]  Roberto Romero,et al.  Inflammation in preterm and term labour and delivery. , 2006, Seminars in fetal & neonatal medicine.

[160]  J. Penninger,et al.  Lessons from SARS: control of acute lung failure by the SARS receptor ACE2 , 2006, Journal of Molecular Medicine.

[161]  F. Martinon,et al.  Gout-associated uric acid crystals activate the NALP3 inflammasome , 2006, Nature.

[162]  J. Gu,et al.  Orchitis: A Complication of Severe Acute Respiratory Syndrome (SARS)1 , 2006, Biology of reproduction.

[163]  Mark Chappell,et al.  A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury , 2005, Nature Medicine.

[164]  G. Navis,et al.  Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis , 2004, The Journal of pathology.

[165]  John L. Sullivan,et al.  Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus , 2003, Nature.

[166]  K. Kato,et al.  Treatment of Oligoasthenozoospermia with Tranilast, a Mast Cell Blocker, After Long-Term Administration , 2002, Archives of andrology.

[167]  K. Whittington,et al.  Relative contribution of leukocytes and of spermatozoa to reactive oxygen species production in human sperm suspensions. , 1999, International journal of andrology.

[168]  M. Griswold.  The central role of Sertoli cells in spermatogenesis. , 1998, Seminars in cell & developmental biology.

[169]  B. Oh,et al.  THE EFFECT OF SPINAL CORD INJURY ON SPERMATOGENESIS IN RATS , 1997 .

[170]  R. Kelly.  Pregnancy maintenance and parturition: the role of prostaglandin in manipulating the immune and inflammatory response. , 1994, Endocrine reviews.

[171]  J. Halgunset,et al.  Cytokine levels in amniotic fluid and inflammatory changes in the placenta from normal deliveries at term. , 1994, European journal of obstetrics, gynecology, and reproductive biology.

[172]  D. Meldrum.  Female reproductive aging — Ovarian and uterine factors , 1993, Fertility and sterility.