Capecitabine, irinotecan, oxaliplatin (CAPIRINOX) and concomitant irradiation in advanced rectal cancer: the Lyon R-02-01 phase I trial.

[1]  R. Jain,et al.  Complete pathological response to bevacizumab and chemoradiation in advanced rectal cancer , 2007, Nature Clinical Practice Oncology.

[2]  R. Grobholz,et al.  A phase II study of capecitabine and irinotecan in combination with concurrent pelvic radiotherapy (CapIri-RT) as neoadjuvant treatment of locally advanced rectal cancer , 2007, British Journal of Cancer.

[3]  C. Sempoux,et al.  Phase I/II study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer. , 2006, Annals of oncology : official journal of the European Society for Medical Oncology.

[4]  Laurence Collette,et al.  Chemotherapy with preoperative radiotherapy in rectal cancer. , 2006, The New England journal of medicine.

[5]  A. Figer,et al.  Preoperative chemoradiation in rectal cancer: Retrospective comparison between capecitabine and continuous infusion of 5‐fluorouracil , 2006, Journal of surgical oncology.

[6]  R. Fietkau,et al.  Concurrent chemoradiation with capecitabine and weekly irinotecan as preoperative treatment for rectal cancer: results from a phase I/II study , 2006, British Journal of Cancer.

[7]  W. Yoon,et al.  Comparison of the Efficacy of Oral Capecitabine versus Bolus 5-FU in Preoperative Radiotherapy of Locally Advanced Rectal Cancer , 2006, Journal of Korean medical science.

[8]  C. Sempoux,et al.  Phase II study of preoperative oxaliplatin, capecitabine and external beam radiotherapy in patients with rectal cancer: the RadiOxCape study. , 2005, Annals of oncology : official journal of the European Society for Medical Oncology.

[9]  R. Glynne-Jones,et al.  A phase I/II study of oxaliplatin when added to 5-fluorouracil and leucovorin and pelvic radiation in locally advanced rectal cancer: a Colorectal Clinical Oncology Group (CCOG) study , 2005, British Journal of Cancer.

[10]  J. Zalcberg,et al.  A phase I trial of preoperative radiotherapy and capecitabine for locally advanced, potentially resectable rectal cancer , 2004, British Journal of Cancer.

[11]  J. Berlin,et al.  Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. , 2004, The New England journal of medicine.

[12]  W. Hohenberger,et al.  Phase I/II trial of capecitabine, oxaliplatin, and radiation for rectal cancer. , 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[13]  O. Dent,et al.  Surgical Technique and Survival in Patients Having a Curative Resection for Colon Cancer , 2003, Diseases of the colon and rectum.

[14]  A. Dicker,et al.  Tumor response to ionizing radiation combined with antiangiogenesis or vascular targeting agents: exploring mechanisms of interaction. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

[15]  P. Adeleine,et al.  Preoperative concurrent chemoradiotherapy in locally advanced rectal cancer with high-dose radiation and oxaliplatin-containing regimen: the Lyon R0-04 phase II trial. , 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[16]  A. Hinke,et al.  Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[17]  K. Song,et al.  Preoperative chemoradiation using oral capecitabine in locally advanced rectal cancer. , 2002, International journal of radiation oncology, biology, physics.

[18]  R. Peto,et al.  Adjuvant radiotherapy for rectal cancer: a systematic overview of 8507 patients from 22 randomised trials , 2001, The Lancet.

[19]  H. Johansson,et al.  The Stockholm II trial on preoperative radiotherapy in rectal carcinoma , 2001, Cancer.

[20]  P. Romestaing,et al.  Addition of oxaliplatin to continuous fluorouracil, l-folinic acid, and concomitant radiotherapy in rectal cancer: the Lyon R 97-03 phase I trial. , 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[21]  L Pagliaro,et al.  Preoperative radiotherapy for resectable rectal cancer: A meta-analysis. , 2000, JAMA.

[22]  C. Wilson,et al.  Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. , 2000, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[23]  M. van Glabbeke,et al.  New guidelines to evaluate the response to treatment in solid tumors , 2000, Journal of the National Cancer Institute.

[24]  L. Påhlman,et al.  Preoperative irradiation affects functional results after surgery for rectal cancer , 1998, Diseases of the colon and rectum.

[25]  T. Rich,et al.  Potentiation of murine MCa-4 carcinoma radioresponse by 9-amino-20(S)-camptothecin. , 1997, Cancer research.

[26]  L Påhlman,et al.  Improved survival with preoperative radiotherapy in resectable rectal cancer. , 1997, The New England journal of medicine.

[27]  A. Recht,et al.  Sphincter preservation therapy for distal rectal carcinoma , 1997, Cancer.

[28]  B. Cedermark,et al.  Randomized study on preoperative radiotherapy in rectal carcinoma , 1996, Annals of Surgical Oncology.

[29]  P. Burtin,et al.  [Consensus conference 1994 on treatments of cancer of the rectum: what can we expect from endorectal ultrasonography?]. , 1995, Gastroenterologie clinique et biologique.

[30]  L. Påhlman,et al.  Preoperative or postoperative irradiation in adenocarcinoma of the rectum: Final treatment results of a randomized trial and an evaluation of late secondary effects , 1993, Diseases of the colon and rectum.

[31]  L. Påhlman,et al.  Pre- or postoperative radiotherapy in rectal and rectosigmoid carcinoma. Report from a randomized multicenter trial. , 1990, Annals of surgery.

[32]  A. Rauth,et al.  5-Fluorouracil infusions and fractionated doses of radiation: studies with a murine squamous cell carcinoma. , 1987, International journal of radiation oncology, biology, physics.

[33]  R. Glynne-Jones,et al.  A phase I dose escalation study of continuous oral capecitabine in combination with oxaliplatin and pelvic radiation (XELOX-RT) in patients with locally advanced rectal cancer. , 2006, Annals of oncology : official journal of the European Society for Medical Oncology.

[34]  Daniel J Sargent,et al.  A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[35]  L. Påhlman Adjuvant radiotherapy for rectal cancer: a systematic overview of 8507 patients from 22 randomised trials. Commentary , 2001 .

[36]  F. Lévi,et al.  Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first-line treatment of metastatic colorectal cancer. , 2000, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[37]  J. Tepper,et al.  202 Oxaliplatin: In vitro evidence of its radiation sensitizing activity — preclinical observations relevant to clinical trials , 1999 .

[38]  Enker We Mesorectal excision (TME) in the operative treatment of rectal cancer. , 1999 .