Pyrrolizidine alkaloid isoline-induced oxidative injury in various mouse tissues.

[1]  N. Nieto,et al.  [Hepatocyte oxidant stress and alcoholic liver disease]. , 2008, Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva.

[2]  Zheng-Tao Wang,et al.  In Vitro Metabolism of Isoline, a Pyrrolizidine Alkaloid from Ligularia duciformis, by Rodent Liver Microsomal Esterase and Enhanced Hepatotoxicity by Esterase Inhibitors , 2007, Drug Metabolism and Disposition.

[3]  F. Regoli,et al.  Seasonal variability of oxidative biomarkers, lysosomal parameters, metallothioneins and peroxisomal enzymes in the Mediterranean mussel Mytilus galloprovincialis from Adriatic Sea. , 2006, Chemosphere.

[4]  Li Sun,et al.  Inflammation of different tissues in spontaneously hypertensive rats. , 2006, Sheng li xue bao : [Acta physiologica Sinica].

[5]  David A. Brenner,et al.  Mechanisms of Liver Injury. I. TNF-α-induced liver injury: role of IKK, JNK, and ROS pathways , 2006 .

[6]  R. Cooper,et al.  Physicochemical and metabolic basis for the differing neurotoxicity of the pyrrolizidine alkaloids, trichodesmine and monocrotaline , 1996, Neurochemical Research.

[7]  Wang Zai 2-Dimensional Electrophoresis Analysis of the Hydrophilic Proteins in Acute Intoxicated Mouse Liver Induced by Isoline , 2006 .

[8]  E. Bassenge,et al.  Oxidativer Stress und kardiovaskuläre Erkrankungen , 2005 .

[9]  Ge Lin,et al.  Pyrrolizidine Alkaloids—Genotoxicity, Metabolism Enzymes, Metabolic Activation, and Mechanisms , 2004, Drug metabolism reviews.

[10]  Zheng-Tao Wang,et al.  Simultaneous determination of isoline and its two major metabolites using high-performance liquid chromatography. , 2004, Journal of analytical toxicology.

[11]  I. Ebihara,et al.  Effects of LDL Apheresis and Vitamin E-Modified Membrane on Carotid Atherosclerosis in Hemodialyzed Patients with Arteriosclerosis obliterans , 2003, Kidney and Blood Pressure Research.

[12]  Debasis Bagchi,et al.  Comparative effects of TCDD, endrin, naphthalene and chromium (VI) on oxidative stress and tissue damage in the liver and brain tissues of mice. , 2002, Toxicology.

[13]  D. Sheehan,et al.  Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily. , 2001, The Biochemical journal.

[14]  M. Spiteri,et al.  Glutathione-S-transferase family of enzymes. , 2001, Mutation research.

[15]  J. Arthur The glutathione peroxidases , 2001, Cellular and Molecular Life Sciences CMLS.

[16]  R. F. Huang,et al.  Folate depletion and elevated plasma homocysteine promote oxidative stress in rat livers. , 2001, The Journal of nutrition.

[17]  E. Roeder Medicinal plants in China containing pyrrolizidine alkaloids. , 2000, Die Pharmazie.

[18]  G. Gordon,et al.  Induction of cytochrome P450 enzymes in the livers of rats treated with the pyrrolizidine alkaloid retrorsine. , 2000, Experimental and molecular pathology.

[19]  A. Belló-Klein,et al.  Effects of ischemia and reperfusion on oxidative stress in hepatic cirrhosis induced by carbon tetrachloride in rats. , 2000, The Kobe journal of medical sciences.

[20]  S. Cook,et al.  Regulation of bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes: association with changes in mitochondrial membrane potential. , 1999, Circulation research.

[21]  B. Stegelmeier,et al.  Pyrrolizidine alkaloid plants, metabolism and toxicity. , 1999, Journal of natural toxins.

[22]  R. Cooper,et al.  The relationship between reactivity of metabolites of pyrrolizidine alkaloids and extrahepatic toxicity. , 1999, Proceedings of the Western Pharmacology Society.

[23]  J. Lancaster,et al.  Rat liver postischemic lipid peroxidation and vasoconstriction depend on ischemia time. , 1998, Free radical biology & medicine.

[24]  S C Rowat,et al.  Integrated defense system overlaps as a disease model: with examples for multiple chemical sensitivity. , 1998, Environmental health perspectives.

[25]  J J Strain,et al.  The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay. , 1996, Analytical biochemistry.

[26]  C C Yan,et al.  Effects of monocrotaline, a pyrrolizidine alkaloid, on glutathione metabolism in the rat. , 1996, Biochemical pharmacology.

[27]  R. Roth,et al.  Monocrotaline pyrrole‐induced changes in angiotensin‐converting enzyme activity of cultured pulmonary artery endothelial cells , 1993, British journal of pharmacology.

[28]  J. Wagner,et al.  Effects of monocrotaline pyrrole on cultured rat pulmonary endothelium. , 1993, Toxicology and applied pharmacology.

[29]  Seamus J. Martin,et al.  Dose‐dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli , 1991, Cell proliferation.

[30]  D. Wilson,et al.  Changes in type II cell populations in monocrotaline pneumotoxicity. , 1990, The American journal of pathology.

[31]  P. Cheeke Toxicity and metabolism of pyrrolizidine alkaloids. , 1988, Journal of animal science.

[32]  I. Fridovich Biological effects of the superoxide radical. , 1986, Archives of biochemistry and biophysics.

[33]  J. Kay,et al.  Lung angiotensin converting enzyme activity in monocrotaline pulmonary hypertension. , 1984, Thorax.

[34]  H. Aebi,et al.  Catalase in vitro. , 1984, Methods in enzymology.

[35]  D. Heath,et al.  Effects of phenobarbitone, cinnarizine, and zoxazolamine on the development of right ventricular hypertrophy and hypertensive pulmonary vascular disease in rats treated with monocrotaline. , 1976, Cardiovascular research.

[36]  W B Jakoby,et al.  Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. , 1974, The Journal of biological chemistry.

[37]  S. Orrenius,et al.  NADPH-dependent reductase solubilized from microsomes by peroxidation and its activity. , 1974, Biochemical and biophysical research communications.

[38]  H. Ganther,et al.  Selenium: Biochemical Role as a Component of Glutathione Peroxidase , 1973, Science.