Chemiluminescence and electrochemiluminescence applications of metal nanoclusters

Due to strong photoluminescence, extraordinary photostability, excellent biocompatibility, and good water-solubility, metal nanoclusters have attracted enormous attention since discovered. They are found to be novel fluorescence labels for biological applications and environmental monitoring. Recently the chemiluminescence (CL) or electrochemiluminescence (ECL) of metal nanoclusters has received increasing attention. This review covers recent vibrant developments in this field of the past 5 years, and highlights different functions of metal nanoclusters in various CL and ECL systems, such as luminophores, catalysts, and quenchers. Latest synthetic methods of metal nanoclusters used in CL or ECL are also summarized. Furthermore, we discuss some perspectives and critical challenges of this field in the near future.

[1]  Y. Tong,et al.  Progress in Molecular Imprinting Electrochemiluminescence Analysis , 2015 .

[2]  Yongdong Jin,et al.  Fluorescent Au nanoclusters: recent progress and sensing applications , 2014 .

[3]  Ke Wang,et al.  A nano-TiO2 supported AuAg alloy nanocluster functionalized electrode for sensitizing the electrochemiluminescent analysis , 2013 .

[4]  Hongyuan Chen,et al.  Silver Nanoclusters for High-Efficiency Quenching of CdS Nanocrystal Electrochemiluminescence and Sensitive Detection of microRNA. , 2015, ACS applied materials & interfaces.

[5]  Jianmin Wu,et al.  Image-contrast technology based on the electrochemiluminescence of porous silicon and its application in fingerprint visualization. , 2014, Angewandte Chemie.

[6]  G. Nienhaus,et al.  Ultra-small fluorescent metal nanoclusters: Synthesis and biological applications , 2011 .

[7]  Chao Lu,et al.  Gold Nanoclusters@Ru(bpy)₃²⁺-Layered Double Hydroxide Ultrathin Film as a Cathodic Electrochemiluminescence Resonance Energy Transfer Probe. , 2015, Analytical chemistry.

[8]  Jinhua Huang,et al.  A novel solid-state electrochemiluminescence sensor for the determination of hydrogen peroxide based on an Au nanocluster-silica nanoparticle nanocomposite. , 2013, The Analyst.

[9]  R. Dickson,et al.  Photoactivated fluorescence from individual silver nanoclusters. , 2001, Science.

[10]  Guobao Xu,et al.  Chemiluminescence of creatinine/H2O2/Co(2+) and its application for selective creatinine detection. , 2016, Biosensors & bioelectronics.

[11]  E. Wang,et al.  Controlling the synthesis and assembly of fluorescent Au/Ag alloy nanoclusters. , 2015, Chemical communications.

[12]  Guobao Xu,et al.  Wireless electrochemiluminescence with disposable minidevice. , 2014, Analytical chemistry.

[13]  Jun‐Jie Zhu,et al.  Fabrication of a dispersible graphene/gold nanoclusters hybrid and its potential application in electrogenerated chemiluminescence. , 2011, Chemical communications.

[14]  E. Wang,et al.  Water-dispersible near-infrared Ag2S nanoclusters with tunable fluorescence for bioimaging application , 2015 .

[15]  Ling Zhang,et al.  Copper nanoclusters as peroxidase mimetics and their applications to H2O2 and glucose detection. , 2013, Analytica chimica acta.

[16]  Guonan Chen,et al.  Electrogenerated chemiluminescence from Au nanoclusters. , 2011, Chemical communications.

[17]  Guobao Xu,et al.  Glucose biosensor based on gold nanoparticle-catalyzed luminol electrochemiluminescence on a three-dimensional sol-gel network , 2008 .

[18]  H. Ju,et al.  Ratiometric electrochemiluminescent strategy regulated by electrocatalysis of palladium nanocluster for immunosensing. , 2016, Biosensors & bioelectronics.

[19]  Zhi‐Feng Zhang,et al.  Size-Dependent Inhibition and Enhancement by Gold Nanoparticles of Luminol−Ferricyanide Chemiluminescence , 2007 .

[20]  Mahdi Hesari,et al.  Interrogating near-infrared electrogenerated chemiluminescence of Au25(SC2H4Ph)18(+) clusters. , 2012, Journal of the American Chemical Society.

[21]  Hongying Liu,et al.  Electrogenerated chemiluminescence of Au nanoclusters for the detection of dopamine. , 2011, Analytical chemistry.

[22]  Guobao Xu,et al.  Label-free signal-on ATP aptasensor based on the remarkable quenching of tris(2,2'-bipyridine)ruthenium(II) electrochemiluminescence by single-walled carbon nanohorn. , 2015, Chemical communications.

[23]  Jin-Ming Lin,et al.  Aggregation-induced structure transition of protein-stabilized zinc/copper nanoclusters for amplified chemiluminescence. , 2015, ACS nano.

[24]  Jian Sun,et al.  Synthesis of functionalized fluorescent gold nanoclusters for acid phosphatase sensing. , 2015, Nanoscale.

[25]  E. Wang,et al.  Organic-soluble fluorescent Au8 clusters generated from heterophase ligand-exchange induced etching of gold nanoparticles and their electrochemiluminescence. , 2012, Chemical communications.

[26]  Mahdi Hesari,et al.  Electrogenerated Chemiluminescence of Monodisperse Au144(SC2H4Ph)60 Clusters , 2014 .

[27]  Guobao Xu,et al.  Effect of hydroxyl and amino groups on electrochemiluminescence activity of tertiary amines at low tris(2,2'-bipyridyl)ruthenium(II) concentrations. , 2010, Talanta.

[28]  Ke Wang,et al.  Strong enhancement of the electrochemiluminescence of luminol by AuAg and PtAg alloy nanoclusters, and its sensitization by phenolic artificial oestrogens , 2014, Microchimica Acta.

[29]  H. Cui,et al.  Lucigenin Chemiluminescence Induced by Noble Metal Nanoparticles in the Presence of Adsorbates , 2007 .

[30]  E. Wang,et al.  Applications of carbon quantum dots in electrochemiluminescence: A mini review , 2014 .

[31]  J. Wilcoxon,et al.  Synthesis, structure and properties of metal nanoclusters. , 2006, Chemical Society reviews.

[32]  Jianping Xie,et al.  Protein-directed synthesis of highly fluorescent gold nanoclusters. , 2009, Journal of the American Chemical Society.

[33]  S. Dong,et al.  Chemiluminescent determination of luminol and hydrogen peroxide using hematin immobilized in the bulk of a carbon paste electrode , 1999 .

[34]  Xiahong Zhang,et al.  Applications of Metal Nanoclusters in Environmental Monitoring , 2015 .

[35]  S. Parveen,et al.  Oligonucleotide-stabilized fluorescent silver nanoclusters for turn-on detection of melamine. , 2012, Biosensors & bioelectronics.

[36]  Ling Zhang,et al.  Seed-mediated growth of noble metal nanocrystals: crystal growth and shape control. , 2013, Nanoscale.

[37]  Guobao Xu,et al.  Thiourea dioxide as a unique eco-friendly coreactant for luminol chemiluminescence in the sensitive detection of luminol, thiourea dioxide and cobalt ions. , 2015, Chemical communications.

[38]  Guobao Xu,et al.  Synthesis of convex hexoctahedral palladium@gold core-shell nanocrystals with {431} high-index facets with remarkable electrochemiluminescence activities. , 2014, ACS nano.

[39]  Guobao Xu,et al.  Detection of ozone based on its striking inhibition of tris(1,10-phenanthroline)ruthenium(II)/glyoxal electrochemiluminescence. , 2014, Chemical communications.

[40]  Tao Li,et al.  Aptamer-based label-free method for hemin recognition and DNA assay by capillary electrophoresis with chemiluminescence detection , 2007, Analytical and bioanalytical chemistry.

[41]  Guobao Xu,et al.  Hydroxylamine-O-sulfonic acid as an efficient coreactant for luminol chemiluminescence for selective and sensitive detection. , 2015, Chemical communications.

[42]  Guobao Xu,et al.  Electrochemiluminescence of tris(2,2′-bipyridyl)ruthenium(II)/pyruvate system in the absence of cerium(III) , 2010 .

[43]  Funan Chen,et al.  Gold nanocluster-enhanced peroxynitrous acid chemiluminescence for high selectivity sensing of nitrite , 2015 .

[44]  H. Ju,et al.  Highly selective detection of microRNA based on distance-dependent electrochemiluminescence resonance energy transfer between CdTe nanocrystals and Au nanoclusters. , 2014, Biosensors & bioelectronics.

[45]  Z. Song,et al.  Photochemical induced formed Au nanomaterial with size and shape controlled by luminol–pepsin chemiluminescence reaction , 2014 .

[46]  Mahdi Hesari,et al.  Thermodynamic and kinetic origins of Au25(0) nanocluster electrochemiluminescence. , 2014, Chemistry.

[47]  Y. Tu,et al.  Cytotoxicity of BSA-Stabilized Gold Nanoclusters: In Vitro and In Vivo Study. , 2015, Small.

[48]  H. Ju,et al.  Target-assistant Zn2+-dependent DNAzyme for signal-on electrochemiluminescent biosensing , 2015 .

[49]  Funan Chen,et al.  Enhanced chemiluminescence of the luminol-hydrogen peroxide system by BSA-stabilized Au nanoclusters as a peroxidase mimic and its application , 2014 .

[50]  Ling Zhang,et al.  Synthesis and electrocatalytic properties of tetrahexahedral, polyhedral, and branched Pd@Au core-shell nanocrystals. , 2013, Chemical communications.

[51]  X. Qu,et al.  Highly sensitive electrochemiluminescent cytosensing using carbon nanodot@Ag hybrid material and graphene for dual signal amplification. , 2013, Chemical communications.

[52]  Guobao Xu,et al.  Fluorescence detection of glutathione reductase activity based on deoxyribonucleic acid-templated silver nanoclusters. , 2013, Analytica chimica acta.

[53]  Z. Song,et al.  Study of captopril pharmacokinetics in rabbit blood with microdialysis based on online generated Au nanoclusters and pepsin–captopril interaction in luminol chemiluminescence , 2014 .

[54]  Yu-fei Hu,et al.  Flow Injection-Chemiluminescence Method for Determination of Hydrocortisone in Human Serum by Using Trivalent Silver Complex , 2015 .

[55]  Mahdi Hesari,et al.  NIR electrochemiluminescence from Au25− nanoclusters facilitated by highly oxidizing and reducing co-reactant radicals , 2014 .

[56]  Funan Chen,et al.  Luminol chemiluminescence enhanced by copper nanoclusters and its analytical application , 2014 .

[57]  Guobao Xu,et al.  Recent advances in electrochemiluminescence. , 2015, Chemical Society reviews.

[58]  Xijuan Yu,et al.  The determination of copper ions based on sensitized chemiluminescence of silver nanoclusters , 2011 .

[59]  Ning Gan,et al.  A novel "dual-potential" electrochemiluminescence aptasensor array using CdS quantum dots and luminol-gold nanoparticles as labels for simultaneous detection of malachite green and chloramphenicol. , 2015, Biosensors & bioelectronics.

[60]  Mahdi Hesari,et al.  Highly efficient electrogenerated chemiluminescence of Au38 nanoclusters. , 2014, ACS nano.

[61]  Guobao Xu,et al.  Ultrasensitive electrochemiluminescent determination of perphenazine at tris(1,10-phenanthroline) ruthenium(II)/Nafion bulk modified carbon nanotube ceramic electrode via solid-phase microextraction , 2015 .

[62]  Y. Sakka,et al.  Luminescent metal nanoclusters: controlled synthesis and functional applications , 2013, Science and technology of advanced materials.

[63]  Erkang Wang,et al.  Metal nanoclusters: New fluorescent probes for sensors and bioimaging , 2014 .

[64]  Hui Wei,et al.  Protein‐ and Peptide‐directed Approaches to Fluorescent Metal Nanoclusters , 2015 .

[65]  Na Li,et al.  Platinum nanoparticle-catalyzed lucigenin–hydrazine chemiluminescence , 2011 .

[66]  S. Dong,et al.  Chemiluminescent Determination of Glucose with a Modified Carbon Paste Electrode , 1999 .

[67]  Yi Lv,et al.  Recent Advances in Analytical Applications of Nanomaterials in Liquid-Phase Chemiluminescence , 2014 .

[68]  Mahdi Hesari,et al.  Near-infrared electrochemiluminescence from Au25(SC2H4Ph)18+ clusters co-reacted with tri-n-propylamine , 2014 .

[69]  Xiliang Luo,et al.  A sensitive chemiluminescence method for the determination of cysteine based on silver nanoclusters , 2012, Microchimica Acta.

[70]  R. Yuan,et al.  An electrogenerated chemiluminescence sensor prepared with a graphene/multiwall carbon nanotube/gold nanocluster hybrid for the determination of phenolic compounds. , 2013, The Analyst.

[71]  Tao Li,et al.  Lead(II)-induced allosteric G-quadruplex DNAzyme as a colorimetric and chemiluminescence sensor for highly sensitive and selective Pb2+ detection. , 2010, Analytical chemistry.

[72]  Ye Teng,et al.  A label-free fluorescent molecular beacon based on DNA-Ag nanoclusters for the construction of versatile Biosensors. , 2015, Biosensors & bioelectronics.

[73]  Lingling Li,et al.  A Facile Microwave Avenue to Electrochemiluminescent Two‐Color Graphene Quantum Dots , 2012 .

[74]  Xiwen He,et al.  Reduced carbon dots versus oxidized carbon dots: photo- and electrochemiluminescence investigations for selected applications. , 2013, Chemistry.

[75]  Hua Cui,et al.  Gold nanoparticle-catalyzed luminol chemiluminescence and its analytical applications. , 2005, Analytical chemistry.

[76]  E. Wang,et al.  Multifunctional near-infrared fluorescent nanoclusters for simultaneous targeted cancer imaging and photodynamic therapy , 2016 .

[77]  Yunhui Li,et al.  Highly efficient quenching of tris(2,2'-bipyridyl)ruthenium(II) electrochemiluminescence by ozone using formaldehyde, methylglyoxal, and glyoxalate as co-reactants and its application to ozone sensing. , 2015, The Analyst.

[78]  Robin H. A. Ras,et al.  Color tunability and electrochemiluminescence of silver nanoclusters. , 2009, Angewandte Chemie.

[79]  Q. Song,et al.  Synthesis, optical properties and applications of ultra-small luminescent gold nanoclusters , 2014 .

[80]  Guobao Xu,et al.  Remarkable increase in luminol electrochemiluminescence by sequential electroreduction and electrooxidation. , 2014, Chemical communications.

[81]  Jian Sun,et al.  Integrated logic gate for fluorescence turn-on detection of histidine and cysteine based on Ag/Au bimetallic nanoclusters-Cu²⁺ ensemble. , 2015, ACS applied materials & interfaces.

[82]  T. Liu,et al.  Sonochemical synthesis of Ag nanoclusters: electrogenerated chemiluminescence determination of dopamine. , 2013, Luminescence : the journal of biological and chemical luminescence.

[83]  R. Jin,et al.  Atomically precise metal nanoclusters: stable sizes and optical properties. , 2015, Nanoscale.

[84]  Z. Song,et al.  Novel preparation and electrochemiluminescence application of luminol functional-Au nanoclusters for ALP determination , 2015 .

[85]  Yingxue Zhang,et al.  Ultrasensitive determination of bisphenol A in water by inhibition of copper nanoclusters-enhanced chemiluminescence from the luminol–KMnO4 system , 2014 .

[86]  S. Parveen,et al.  Highly sensitive fluorescent detection of trypsin based on BSA-stabilized gold nanoclusters. , 2012, Biosensors & bioelectronics.

[87]  Jinghua Yu,et al.  Electrochemiluminescence of blue-luminescent graphene quantum dots and its application in ultrasensitive aptasensor for adenosine triphosphate detection. , 2013, Biosensors & bioelectronics.