CD4+ T cells and TGFβ1/MAPK signal pathway involved in the valvular hyperblastosis and fibrosis in patients with rheumatic heart disease.

[1]  Andrea Beaton,et al.  Global, Regional, and National Burden of Rheumatic Heart Disease, 1990–2015 , 2017, The New England journal of medicine.

[2]  Jiahuai Han,et al.  Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation , 2017, Nature Cell Biology.

[3]  Yuan Qiao,et al.  Resveratrol ameliorates diabetic nephropathy in rats through negative regulation of the p38 MAPK/TGF-β1 pathway , 2017, Experimental and therapeutic medicine.

[4]  G. Karthikeyan,et al.  Acute rheumatic fever and rheumatic heart disease , 2015, Nature Reviews Disease Primers.

[5]  Ziwei Huang,et al.  TGF-β1 and TIMP-4 regulate atrial fibrosis in atrial fibrillation secondary to rheumatic heart disease , 2015, Molecular and Cellular Biochemistry.

[6]  J. R. Smith,et al.  Wharton’s Jelly-Derived Mesenchymal Stromal Cells as a Promising Cellular Therapeutic Strategy for the Management of Graft-versus-Host Disease , 2015, Pharmaceuticals.

[7]  R. Chen,et al.  Reduced beta 2 glycoprotein I improves diabetic nephropathy via inhibiting TGF-β1-p38 MAPK pathway. , 2015, International journal of clinical and experimental pathology.

[8]  J. Banchereau,et al.  Human CD141+ Dendritic Cells Induce CD4+ T Cells To Produce Type 2 Cytokines , 2014, The Journal of Immunology.

[9]  C. Lan,et al.  Tacrolimus abrogates TGF‐β1‐induced type I collagen production in normal human fibroblasts through suppressing p38MAPK signalling pathway: implications on treatment of chronic atopic dermatitis lesions , 2014, Journal of the European Academy of Dermatology and Venereology : JEADV.

[10]  B. Becher,et al.  TGF-β Signalling Is Required for CD4+ T Cell Homeostasis But Dispensable for Regulatory T Cell Function , 2013, PLoS biology.

[11]  Joseph Chen,et al.  Cadherin-11 Regulates Cell–Cell Tension Necessary for Calcific Nodule Formation by Valvular Myofibroblasts , 2013, Arteriosclerosis, thrombosis, and vascular biology.

[12]  V. Trehan,et al.  Regulatory T-cell deficiency in rheumatic heart disease: a preliminary observational study. , 2013, The Journal of heart valve disease.

[13]  Joshua D. Hutcheson,et al.  5-HT(2B) antagonism arrests non-canonical TGF-β1-induced valvular myofibroblast differentiation. , 2012, Journal of molecular and cellular cardiology.

[14]  M. Cunningham.  Streptococcus and rheumatic fever , 2012, Current opinion in rheumatology.

[15]  T. Bellón,et al.  Subepithelial collagen deposition, profibrogenic cytokine gene expression, and changes after prolonged fluticasone propionate treatment in adult eosinophilic esophagitis: a prospective study. , 2011, The Journal of allergy and clinical immunology.

[16]  Nidhal Abdul-Auhaimena,et al.  Functional and Developmental Analysis of CD4+CD25+ Regulatory T Cells under the Influence of Streptococcal M Protein in Rheumatic Heart Disease , 2011, Iranian journal of medical sciences.

[17]  L. Rénia,et al.  TGF-beta activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II-infused mice. , 2010, The Journal of clinical investigation.

[18]  W. Yang,et al.  Overexpression of Transforming Growth Factor-β1 in the Valvular Fibrosis of Chronic Rheumatic Heart Disease , 2008, Journal of Korean medical science.

[19]  P. Chopra,et al.  Pathology and pathogenesis of rheumatic heart disease. , 2007, Indian journal of pathology & microbiology.

[20]  De-Pei Liu,et al.  Coordinated changes of histone modifications, transcription factors and p38/MAPK signaling pathway contribute to apicidin inducement of human fetal hemoglobin expression in K562 cells , 2007 .

[21]  A. Toubert,et al.  Mimicry in Recognition of Cardiac Myosin Peptides by Heart-Intralesional T Cell Clones from Rheumatic Heart Disease1 , 2006, The Journal of Immunology.

[22]  W. Hildebrand,et al.  T Cell Mimicry and Epitope Specificity of Cross-Reactive T Cell Clones from Rheumatic Heart Disease1 , 2005, The Journal of Immunology.

[23]  N. Kutukculer,et al.  Inverse relationship between the ratio of ICAM-1 expressing lymphocytes and serum TGF-β1 concentrations in acute rheumatic fever , 2005 .

[24]  A. Zuckermann,et al.  Differential Role of TGF‐β1/bFGF and ET‐1 in Graft Fibrosis in Heart Failure Patients , 2005, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[25]  A. Rudensky,et al.  TGF-β1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells , 2005, The Journal of experimental medicine.

[26]  M. Nishimura,et al.  Simultaneous generation of CD8+ and CD4+ melanoma-reactive T cells by retroviral-mediated transfer of a single T-cell receptor. , 2005, Cancer research.

[27]  Matthias Boehm,et al.  cAMP levels inhibit TGF‐β‐induced expression of extracellular matrix (ECM) components by interfering with the SMAD pathway. A potential effector mechanism of hormones signaling via cAMP? , 2005 .

[28]  R. Levy,et al.  Progression of aortic valve stenosis: TGF-beta1 is present in calcified aortic valve cusps and promotes aortic valve interstitial cell calcification via apoptosis. , 2003, The Annals of thoracic surgery.

[29]  A. Sevanian,et al.  Up‐regulation of the fibrogenic cytokine TGF‐β1 by oxysterols: a mechanistic link between cholesterol and atherosclerosis , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[30]  M. Martin,et al.  Antifibrotic action of Cu/Zn SOD is mediated by TGF-beta1 repression and phenotypic reversion of myofibroblasts. , 2001, Free radical biology & medicine.

[31]  A. Toubert,et al.  Molecular evidence for antigen-driven immune responses in cardiac lesions of rheumatic heart disease patients. , 2000, International immunology.

[32]  N. Ganguly,et al.  Superantigen‐induced T cell responses in acute rheumatic fever and chronic rheumatic heart disease patients , 1999, Clinical and experimental immunology.