The heparin-Ca(2+) interaction: the influence of the O-sulfation pattern on binding.

[1]  U. Lindahl.  ‘Heparin’ – from anticoagulant drug into the new biology , 2000, Glycoconjugate Journal.

[2]  J. Angulo,et al.  Synthesis and structural study of two new heparin-like hexasaccharides. , 2003, Organic & biomolecular chemistry.

[3]  J. Angulo,et al.  A molecular dynamics description of the conformational flexibility of the L-iduronate ring in glycosaminoglycans. , 2003, Chemical communications.

[4]  J. Angulo,et al.  The Heparin−Ca2+ Interaction: Structure of the Ca2+ Binding Site , 2002 .

[5]  Djamal Bouzida,et al.  Complexity and simplicity of ligand-macromolecule interactions: the energy landscape perspective. , 2002, Current opinion in structural biology.

[6]  J. Åqvist,et al.  Ligand binding affinities from MD simulations. , 2002, Accounts of chemical research.

[7]  M. Redondo-Horcajo,et al.  The Activation of Fibroblast Growth Factors by Heparin: Synthesis, Structure, and Biological Activity of Heparin‐Like Oligosaccharides , 2001, Chembiochem : a European journal of chemical biology.

[8]  R. Linhardt,et al.  Order out of complexity--protein structures that interact with heparin. , 2001, Current opinion in structural biology.

[9]  B. Seaton,et al.  Annexin V--heparin oligosaccharide complex suggests heparan sulfate--mediated assembly on cell surfaces. , 2001, Structure.

[10]  B. Casu,et al.  Structure and biological interactions of heparin and heparan sulfate. , 2001, Advances in carbohydrate chemistry and biochemistry.

[11]  J. Angulo,et al.  Interaction of heparin with Ca2+: A model study with a synthetic heparin‐like hexasaccharide , 2000 .

[12]  M. Forster,et al.  Conformation and dynamics of heparin and heparan sulfate. , 2000, Glycobiology.

[13]  E. Yates,et al.  Effect of substitution pattern on 1H, 13C NMR chemical shifts and 1J(CH) coupling constants in heparin derivatives. , 2000, Carbohydrate research.

[14]  S. Pérez,et al.  Conformational and configurational features of acidic polysaccharides and their interactions with calcium ions: a molecular modeling investigation. , 1999, Carbohydrate research.

[15]  J. Hirsh,et al.  Heparin Binding Proteins Contribution to Heparin Rebound After Cardiopulmonary Bypass , 1993, Circulation.

[16]  J. Peng,et al.  Multinuclear magnetic resonance studies of the interaction of inorganic cations with heparin. , 1995, Carbohydrate research.

[17]  Robert J. Woods,et al.  Molecular Mechanical and Molecular Dynamic Simulations of Glycoproteins and Oligosaccharides. 1. GLYCAM_93 Parameter Development , 1995 .

[18]  Joshua Jortner,et al.  Modelling of Biomolecular Structures and Mechanisms , 1995 .

[19]  A. Drake,et al.  The effect of variation of substitution on the solution conformation of heparin: a spectroscopic and molecular modelling study. , 1994, Carbohydrate research.

[20]  J. Xu,et al.  An essential heparin-binding domain in the fibroblast growth factor receptor kinase. , 1993, Science.

[21]  J. Keeler,et al.  Absorption-mode two-dimensional NMR spectra recorded using pulsed field gradients , 1991 .

[22]  K. Holme,et al.  Marked stereoselectivity in the binding of copper ions by heparin. Contrasts with the binding of gadolinium and calcium ions. , 1990, Carbohydrate research.

[23]  K. Holme,et al.  Observations on cation-binding characteristics and nuclear magnetic resonance spectra of the N-carboxymethyl and N-acetyl analogs of heparin , 1990 .

[24]  B. Perly,et al.  Conformer populations of L-iduronic acid residues in glycosaminoglycan sequences. , 1990, Carbohydrate research.

[25]  Ad Bax,et al.  MLEV-17-based two-dimensional homonuclear magnetization transfer spectroscopy , 1985 .

[26]  P. Goodford.  A computational procedure for determining energetically favorable binding sites on biologically important macromolecules. , 1985, Journal of medicinal chemistry.

[27]  K. Wüthrich,et al.  Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins. , 1983, Biochemical and biophysical research communications.

[28]  A. Perlin,et al.  An essential role for the 2-sulfamino group in the interaction of calcium ion with heparin , 1982 .

[29]  Richard R. Ernst,et al.  Investigation of exchange processes by two‐dimensional NMR spectroscopy , 1979 .

[30]  Gerald S. Manning,et al.  Counterion binding in polyelectrolyte theory , 1979 .