Transforming growth factor‐β1‐induced CD4+CD25+ regulatory T cells in vitro reverse and prevent a murine lupus‐like syndrome of chronic graft‐versus‐host disease

Background  The suppressive mechanism of CD4+CD25+ regulatory T cells (Tregs) is poorly understood. It is also not known how to obtain enough peripheral Tregs, and how to make them effective in ameliorating a murine lupus‐like syndrome of chronic graft‐versus‐host disease (cGVHD).

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