DNA chip technolgy

A mini‐revolution is sweeping the world of science and medicine. DNA chip or microarray technology will have a more profound impact than other recent major advances, including DNA sequencing and the polymerase chain reaction (PCR). This mini‐review explains the technology, its scope, and impact on science and medicine, as well as its cost and possible limitations. Copyright © 1999 John Wiley & Sons, Ltd.

[1]  J. Sikela,et al.  Use of 3' untranslated sequences of human cDNAs for rapid chromosome assignment and conversion to STSs: implications for an expression map of the genome. , 1991, Nucleic acids research.

[2]  K. Kinzler,et al.  Serial Analysis of Gene Expression , 1995, Science.

[3]  Ronald W. Davis,et al.  Quantitative phenotypic analysis of yeast deletion mutants using a highly parallel molecular bar–coding strategy , 1996, Nature Genetics.

[4]  A. Pardee,et al.  Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. , 1992, Science.

[5]  Kousaku Okubo,et al.  Large scale cDNA sequencing for analysis of quantitative and qualitative aspects of gene expression , 1992, Nature Genetics.

[6]  P. Brown,et al.  Parallel human genome analysis: microarray-based expression monitoring of 1000 genes. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[7]  D. Gerhold,et al.  It's the genes! EST access to human genome content , 1996, BioEssays : news and reviews in molecular, cellular and developmental biology.

[8]  K. Bendtzen,et al.  Increased In Vivo Antibody Activity Against Interferon α, Interleukin-1α, and Interleukin-6 After High-Dose Ig Therapy , 1997 .

[9]  Carol A. Dahl,et al.  New opportunities for uncovering the molecular basis of cancer , 1997, Nature Genetics.

[10]  P. Brown,et al.  A DNA microarray system for analyzing complex DNA samples using two-color fluorescent probe hybridization. , 1996, Genome research.

[11]  P. Brown,et al.  Exploring the metabolic and genetic control of gene expression on a genomic scale. , 1997, Science.

[12]  P. Brown,et al.  Genomics and human disease—variations on variation , 1998, Nature Genetics.

[13]  F Costanzo,et al.  Cloning of several cDNA segments coding for human liver proteins. , 1983, The EMBO journal.

[14]  A. Pardee,et al.  Distribution and cloning of eukaryotic mRNAs by means of differential display: refinements and optimization. , 1993, Nucleic acids research.

[15]  S. Nelson,et al.  Linkage-disequilibrium mapping without genotyping , 1998, Nature Genetics.

[16]  L. Penland,et al.  Use of a cDNA microarray to analyse gene expression patterns in human cancer , 1996, Nature Genetics.

[17]  Ronald W. Davis,et al.  Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray , 1995, Science.