Dopamine transporter binding in Gilles de la Tourette syndrome: a [123I]FP‐CIT/SPECT study

Objective:  To investigate dopamine transporter binding in Gilles de la Tourette syndrome (GTS) with SPECT and [123I]FP‐CIT.

[1]  J. Neumeyer,et al.  Comparison of iodine-123 labelled 2β-carbomethoxy-3β-(4-iodophenyl)tropane and 2β-carbomethoxy-3β-(4-iodophenyl)-N-(3-fluoropropyl)nortropane for imaging of the dopamine transporter in the living human brain , 1995, European Journal of Nuclear Medicine.

[2]  T. Reader,et al.  Neuroleptics and Dopamine Transporters , 2004, Neurochemical Research.

[3]  John P Seibyl,et al.  Unaltered dopamine transporter availability in adult attention deficit hyperactivity disorder. , 2002, The American journal of psychiatry.

[4]  J. Seibyl,et al.  Age-related decline in dopamine transporters: analysis of striatal subregions, nonlinear effects, and hemispheric asymmetries. , 2002, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

[5]  S. Kasper,et al.  No change in striatal dopamine re-uptake site density in psychotropic drug naive and in currently treated Tourette’s disorder patients: a [123I]-β-CIT SPECT-study , 2001, European Neuropsychopharmacology.

[6]  Reinhard Dengler,et al.  Dopamine transporter binding in Gilles de la Tourette syndrome , 2000, Journal of Neurology.

[7]  R. Albin,et al.  Striatal presynaptic monoaminergic vesicles are not increased in Tourette’s syndrome , 1999, Neurology.

[8]  M. Ernst,et al.  High presynaptic dopaminergic activity in children with Tourette's disorder. , 1999, Journal of the American Academy of Child and Adolescent Psychiatry.

[9]  T. Reader,et al.  Effects of antipsychotic drugs on dopamine and serotonin contents and metabolites, dopamine and serotonin transporters, and serotonin1A receptors , 1999, Journal of Neural Transmission.

[10]  Andreas Heinz,et al.  Tourette's syndrome , 1998, Neurology.

[11]  Bradley S. Peterson,et al.  Course of Tic Severity in Tourette Syndrome: The First Two Decades , 1998, Pediatrics.

[12]  D. Weinberger,et al.  Tourette's syndrome: [I-123]beta-CIT SPECT correlates of vocal tic severity. , 1998, Neurology.

[13]  A. Gjedde,et al.  D2-like dopamine receptor density in Tourette syndrome measured by PET. , 1997, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[14]  A. Antonini,et al.  The metabolic anatomy of Tourette's syndrome , 1997, Neurology.

[15]  R. Coppola,et al.  Tourette Syndrome: Prediction of Phenotypic Variation in Monozygotic Twins by Caudate Nucleus D2 Receptor Binding , 1996, Science.

[16]  C. McDougle,et al.  [123I]beta-CIT SPECT imaging of striatal dopamine transporter binding in Tourette's disorder. , 1995, The American journal of psychiatry.

[17]  M. Trimble,et al.  Brain Perfusion Abnormalities in Gilles de la Tourette's Syndrome , 1995, British Journal of Psychiatry.

[18]  D. Charney,et al.  Age-Related Decline in Striatal Dopamine Transporter Binding with Iodine-123-β-CITSPECT , 1995 .

[19]  D. R. Weinberger,et al.  Cerebral morphometric abnormalities in Tourette's syndrome , 1995, Neurology.

[20]  M. Trimble,et al.  Dopamine receptor availability in Tourette's syndrome , 1994, Psychiatry Research: Neuroimaging.

[21]  G. Sawle,et al.  PET studies of the presynaptic and postsynaptic dopaminergic system in Tourette's syndrome. , 1994, Journal of neurology, neurosurgery, and psychiatry.

[22]  R. Baldessarini,et al.  N-omega-fluoroalkyl analogs of (1R)-2 beta-carbomethoxy-3 beta-(4-iodophenyl)-tropane (beta-CIT): radiotracers for positron emission tomography and single photon emission computed tomography imaging of dopamine transporters. , 1994, Journal of medicinal chemistry.

[23]  Mary M. Robertson,et al.  Annotation: Gilles de la Tourette syndrome--an update. , 1994, Journal of child psychology and psychiatry, and allied disciplines.

[24]  Peter Herscovitch,et al.  The Functional Neuroanatomy of Tourette's Syndrome: An FDG-PET Study. I. Regional Changes in Cerebral Glucose Metabolism Differentiating Patients and Controls , 1993, Neuropsychopharmacology.

[25]  E. Chee,et al.  Volumetric MRI changes in basal ganglia of children with Tourette's syndrome , 1993, Neurology.

[26]  B. Peterson,et al.  Reduced basal ganglia volumes in Tourette's syndrome using three‐dimensional reconstruction techniques from magnetic resonance images , 1993, Neurology.

[27]  J. Jankovic,et al.  Cocaine‐related movement disorders , 1993, Movement disorders : official journal of the Movement Disorder Society.

[28]  M. Trimble,et al.  Elevated frontal cerebral blood flow in Gilles de la Tourette syndrome: A 99Tcm-HMPAO SPECT study , 1992, Psychiatry Research: Neuroimaging.

[29]  S. Woods,et al.  SPECT imaging of cerebral blood flow in Tourette syndrome. , 1992, Advances in neurology.

[30]  G. Sawle,et al.  PET studies on the integrity of the pre and postsynaptic dopaminergic system in Tourette syndrome. , 1992, Advances in neurology.

[31]  H. Singer,et al.  Abnormal dopamine uptake sites in postmortem striatum from patients with tourette's syndrome , 1991, Annals of neurology.

[32]  M. George,et al.  SPET Instrumentation: Characteristics and New Developments , 1991 .

[33]  K. Jellinger,et al.  Dopamine uptake sites and dopamine receptors in Parkinson's disease and schizophrenia. , 1990, European neurology.

[34]  A. Shapiro,et al.  Controlled study of haloperidol, pimozide and placebo for the treatment of Gilles de la Tourette's syndrome. , 1989, Archives of general psychiatry.

[35]  D. Cohen,et al.  The Yale Global Tic Severity Scale: initial testing of a clinician-rated scale of tic severity. , 1989, Journal of the American Academy of Child and Adolescent Psychiatry.

[36]  M. Robertson The Gilles de la Tourette Syndrome: the Current Status , 1989, British Journal of Psychiatry.

[37]  M. Trimble,et al.  The Psychopathology of the Gilles de la Tourette Syndrome , 1988, British Journal of Psychiatry.

[38]  G. Huston The Hospital Anxiety and Depression Scale. , 1987, The Journal of rheumatology.

[39]  E. Richardson Neuropathological studies of Tourette syndrome. , 1982, Advances in neurology.

[40]  J. Cooper The Leyton Obsessional Inventory , 1970, Psychological Medicine.