Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase
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Shawn French | Eric D Brown | Eric Oldfield | S. French | E. Brown | E. Oldfield | N. Strynadka | Maya A. Farha | T. Czarny | L. Worrall | Natalie C J Strynadka | Yang Wang | Maya A Farha | Yang Wang | Tomasz L Czarny | Cullen L Myers | Liam J Worrall | Deborah G Conrady | D. Conrady | C. L. Myers | Tomasz L. Czarny
[1] R. Kishony,et al. Nonoptimal Microbial Response to Antibiotics Underlies Suppressive Drug Interactions , 2009, Cell.
[2] E. Brown,et al. Taking aim at wall teichoic acid synthesis: new biology and new leads for antibiotics , 2013, The Journal of Antibiotics.
[3] A. Emili,et al. Genetic Interaction Maps in Escherichia coli Reveal Functional Crosstalk among Cell Envelope Biogenesis Pathways , 2011, PLoS genetics.
[4] E. Brown,et al. Probing teichoic acid genetics with bioactive molecules reveals new interactions among diverse processes in bacterial cell wall biogenesis. , 2009, Chemistry & biology.
[5] Murodzhon Akhmedov,et al. Large-scale identification and analysis of suppressive drug interactions. , 2014, Chemistry & biology.
[6] M. Webb. A continuous spectrophotometric assay for inorganic phosphate and for measuring phosphate release kinetics in biological systems. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[7] E. Brown,et al. Metabolic suppression identifies new antibacterial inhibitors under nutrient limitation , 2013, Nature chemical biology.
[8] B. Berger-Bächi,et al. Factors influencing methicillin resistance in staphylococci , 2002, Archives of Microbiology.
[9] Eric D Brown,et al. Chemical probes of Escherichia coli uncovered through chemical-chemical interaction profiling with compounds of known biological activity. , 2010, Chemistry & biology.
[10] B. Stockwell,et al. Multicomponent therapeutics for networked systems , 2005, Nature Reviews Drug Discovery.
[11] R. Kishony,et al. Functional classification of drugs by properties of their pairwise interactions , 2006, Nature Genetics.
[12] Pedro M. Pereira,et al. Inhibition of WTA Synthesis Blocks the Cooperative Action of PBPs and Sensitizes MRSA to β-Lactams , 2012, ACS chemical biology.
[13] Remy Chait,et al. Drug interactions modulate the potential for evolution of resistance , 2008, Proceedings of the National Academy of Sciences.
[14] F. Götz,et al. Structure and Biosynthesis of Staphyloxanthin from Staphylococcus aureus* , 2005, Journal of Biological Chemistry.
[15] S. Walker,et al. Teichoic acid biosynthesis as an antibiotic target. , 2013, Current opinion in microbiology.
[16] A. Fraser,et al. Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways , 2006, Nature Genetics.
[17] L. Silver. Viable screening targets related to the bacterial cell wall , 2013, Annals of the New York Academy of Sciences.
[18] R. Kishony,et al. Discovery of a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus. , 2009, ACS chemical biology.
[19] E. Oldfield,et al. Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases , 2007, Proceedings of the National Academy of Sciences.
[20] Gary D Bader,et al. Systematic Genetic Analysis with Ordered Arrays of Yeast Deletion Mutants , 2001, Science.
[21] A. Singh,et al. Synthetic lethal compound combinations reveal a fundamental connection between wall teichoic acid and peptidoglycan biosyntheses in Staphylococcus aureus. , 2011, ACS chemical biology.
[22] Wenjun Zhao,et al. Lesions in Teichoic Acid Biosynthesis in Staphylococcus aureus Lead to a Lethal Gain of Function in the Otherwise Dispensable Pathway , 2006, Journal of bacteriology.
[23] Randy J. Read,et al. Acta Crystallographica Section D Biological , 2003 .
[24] E. Oldfield,et al. Antibacterial drug leads: DNA and enzyme multitargeting. , 2015, Journal of medicinal chemistry.
[25] J. Heijenoort,et al. The murG gene of Escherichia coli codes for the UDP-N-acetylglucosamine: N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase involved in the membrane steps of peptidoglycan synthesis , 1991, Journal of bacteriology.
[26] Use of clomiphene citrate in infertile women: a committee opinion. , 2013, Fertility and sterility.
[27] R. G. Anderson,et al. The mechanism of wall synthesis in bacteria. The organization of enzymes and isoprenoid phosphates in the membrane. , 1972, The Biochemical journal.
[28] R. J. Watkinson,et al. Shared lipid phosphate carrier in the biosynthesis of teichoic acid and peptidoglycan. , 1971, Nature: New biology.
[29] Michael Costanzo,et al. Systematic exploration of synergistic drug pairs , 2011, Molecular systems biology.
[30] Eric D Brown,et al. Antibiotics as probes of biological complexity. , 2011, Nature chemical biology.
[31] R. Homburg. Clomiphene citrate--end of an era? A mini-review. , 2005, Human reproduction.
[32] Eric Langlois,et al. Restoring Methicillin-Resistant Staphylococcus aureus Susceptibility to β-Lactam Antibiotics , 2012, Science Translational Medicine.
[33] William Sinko,et al. Antibacterial drug leads targeting isoprenoid biosynthesis , 2012, Proceedings of the National Academy of Sciences.
[34] Jacob D. Durrant,et al. Non-Bisphosphonate Inhibitors of Isoprenoid Biosynthesis Identified via Computer-Aided Drug Design , 2011, Chemical biology & drug design.
[35] W. Jahnke,et al. Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. , 2010, Nature chemical biology.
[36] A. Tomasz,et al. Methicillin Resistance in Staphylococcus Essential for Expression of High-level Reassessment of the Number of Auxiliary Genes , 2022 .
[37] R. Kishony,et al. Antibiotic interactions that select against resistance , 2007, Nature.
[38] Roy Kishony,et al. Drug interactions and the evolution of antibiotic resistance , 2009, Nature Reviews Microbiology.
[39] E. Brown,et al. Wall Teichoic Acid Polymers Are Dispensable for Cell Viability in Bacillus subtilis , 2006, Journal of bacteriology.
[40] O. Igglessi-Markopoulou,et al. Tetramic and Tetronic Acids as Scaffolds in Bioinorganic and Bioorganic Chemistry , 2010, Bioinorganic chemistry and applications.