Effects of sublethal concentrations of potassium permanganate on nitrogenous waste products of African catfish: Clarias gariepinus (Burchell, 1822)

Changes in the nitrogenous waste product of the fish Clarias gariepinus (Burchell, 1822) subjected to sublethal concentrations (2.0; 6.0and 10.0 mg/L) of potassium permanganate over a period of 192 hours were studied in a semistatic (renewal) system. The nitrogenous waste metabolism is reflected in the changes in total plasma bilirubin, plasma uric acid, plasma creatinine and plasma urea. Slight rise in plasma level of total bilirubin suggest a metabolic disturbance in liver involving defective conjugation and/or excretion of bilirubin; increased creatinine and uric acid concentration in the blood suggest the inability of the kidney to excrete these products, a manifestation of nephritic damage; decreased plasma urea may be attributable to the depleted plasma protein levels.

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