PTPMT1 Inhibition Lowers Glucose through Succinate Dehydrogenase Phosphorylation.

[1]  F. Sánchez‐Madrid,et al.  ROS-triggered phosphorylation of complex II by Fgr kinase regulates cellular adaptation to fuel use. , 2014, Cell metabolism.

[2]  N. Danial,et al.  Changing appetites: the adaptive advantages of fuel choice. , 2014, Trends in cell biology.

[3]  R. Gerszten,et al.  Chemical and metabolomic screens identify novel biomarkers and antidotes for cyanide exposure , 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[4]  D. Green,et al.  Mitochondria and cell signalling , 2012, Journal of Cell Science.

[5]  D. Jeong,et al.  Structure-based virtual screening approach to the discovery of novel PTPMT1 phosphatase inhibitors. , 2012, Bioorganic & medicinal chemistry letters.

[6]  Caiying Guo,et al.  A Critical Role of Mitochondrial Phosphatase Ptpmt1 in Embryogenesis Reveals a Mitochondrial Metabolic Stress-Induced Differentiation Checkpoint in Embryonic Stem Cells , 2011, Molecular and Cellular Biology.

[7]  G. Perkins,et al.  Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis. , 2011, Cell metabolism.

[8]  Ole Nørregaard Jensen,et al.  Phosphoproteome Analysis of Functional Mitochondria Isolated from Resting Human Muscle Reveals Extensive Phosphorylation of Inner Membrane Protein Complexes and Enzymes* , 2010, Molecular & Cellular Proteomics.

[9]  Aaron T. Haselton,et al.  Adult Drosophila melanogaster as a model for the study of glucose homeostasis , 2010, Aging.

[10]  D. Winge,et al.  Succinate dehydrogenase - Assembly, regulation and role in human disease. , 2010, Mitochondrion.

[11]  J. Dixon,et al.  Pharmacological Targeting of the Mitochondrial Phosphatase PTPMT1 , 2010, Journal of Pharmacology and Experimental Therapeutics.

[12]  Junjie Hou,et al.  The profile of mitochondrial proteins and their phosphorylation signaling network in INS-1 beta cells. , 2010, Journal of proteome research.

[13]  S. Carr,et al.  A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology , 2008, Cell.

[14]  A. Brunati,et al.  Identification of the flavoprotein of succinate dehydrogenase and aconitase as in vitro mitochondrial substrates of Fgr tyrosine kinase , 2007, FEBS letters.

[15]  H. McBride,et al.  Mitochondria: More Than Just a Powerhouse , 2006, Current Biology.

[16]  Jesse R. Dixon,et al.  Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic beta cells. , 2005, Molecular cell.

[17]  J. Marín-García,et al.  Mitochondrial signaling pathways: A receiver/integrator organelle , 2004, Molecular and Cellular Biochemistry.

[18]  S. Theander,et al.  Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells. , 2004, Endocrinology.

[19]  B. Wicksteed,et al.  Succinate is a preferential metabolic stimulus-coupling signal for glucose-induced proinsulin biosynthesis translation. , 2002, Diabetes.

[20]  H. Rosen,et al.  Myeloperoxidase-mediated damage to the succinate oxidase system of Escherichia coli. Evidence for selective inactivation of the dehydrogenase component. , 1987, The Journal of biological chemistry.