Compelling P1 substituent affect on metalloprotease binding profile enables the design of a novel cyclohexyl core scaffold with excellent MMP selectivity and HER-2 sheddase inhibition.
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R. Wynn | J. Fridman | P. Scherle | Yanlong Li | M. Covington | B. Metcalf | S. Friedman | W. Yao | Cindy A Marando | Chunhong He | Meizhong Xu | J. Zhuo | Yun-long Li | Kamna Katiyar | Colin Zhang | D. Burns | Ding-Quan Qian | E. Shi
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