4′-α-C-Branched N,O-nucleosides: synthesis and biological properties
暂无分享,去创建一个
D. Iannazzo | R. Romeo | A. Piperno | F. Genovese | A. Mastino | U. Chiacchio | P. Quadrelli | V. Valveri | Corsaro Antonino
[1] A. Rescifina,et al. Enantioselective synthesis of N, O-psiconucleosides , 2003 .
[2] A. Rescifina,et al. Enantioselective syntheses and cytotoxicity of N,O-nucleosides. , 2003, Journal of medicinal chemistry.
[3] Erik De Clercq,et al. New anti‐HIV agents and targets , 2002, Medicinal research reviews.
[4] A. Rescifina,et al. Modified nucleosides. A general and diastereoselective approach to N, O-psiconucleosides , 2002 .
[5] J. Grassi,et al. Synthesis of haptens for the development of immunoassays for the monitoring of intracellular anti-HIV nucleosides and nucleotides , 2001 .
[6] M. Matsuoka,et al. 4′-Ethynyl Nucleoside Analogs: Potent Inhibitors of Multidrug-Resistant Human Immunodeficiency Virus Variants In Vitro , 2001, Antimicrobial Agents and Chemotherapy.
[7] Erik De Clercq,et al. New developments in anti-HIV chemotherapy , 2001 .
[8] S. Shuto,et al. Nucleosides and nucleotides. 185. Synthesis and biological activities of 4'alpha-C-branched-chain sugar pyrimidine nucleosides. , 1999, Journal of medicinal chemistry.
[9] S. Grelli,et al. Identification of nuclei from apoptotic, necrotic, and viable lymphoid cells by using multiparameter flow cytometry. , 1999, Cytometry.
[10] E. Beers. Programmed cell death during plant growth and development , 1997, Cell Death and Differentiation.
[11] S. Grelli,et al. Herpes simplex virus 2 causes apoptotic infection in monocytoid cells , 1997, Cell Death and Differentiation.
[12] M. Fukushima,et al. Nucleosides and Nucleotides. 158. 1-(3-C-Ethynyl-β-d-ribo-pentofuranosyl)- cytosine, 1-(3-C-Ethynyl-β-d-ribo-pentofuranosyl)uracil, and Their Nucleobase Analogues as New Potential Multifunctional Antitumor Nucleosides with a Broad Spectrum of Activity1 , 1996 .
[13] E. Santaniello,et al. Baker’s Yeast Mediated Biohydrogenation of 2-Substituted Allyl Alcohols: Synthesis of Enantiomerically Pure (2S)-3-Benzyloxy-2-methyl-1-propanol , 1996 .
[14] A. Rescifina,et al. Modified dideoxynucleosides: Synthesis of 2′-N-alkyl-3′-hydroxyalkyl-1′,2′-isoxazolidinyl thymidine and 5-fluorouridine derivatives , 1996 .
[15] A. Matsuda,et al. Nucleosides and nucleotides. 141. Chemical stability of a new antitumor nucleoside, 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine in alkaline medium: formation of 2'-C-cyano-2'-deoxy-1-beta-D-ribo-pentofuranosylcytosine and its antitumor activity. , 1995, Journal of medicinal chemistry.
[16] Y. Cheng,et al. Anticancer activity of beta-L-dioxolane-cytidine, a novel nucleoside analogue with the unnatural L configuration. , 1995, Cancer research.
[17] A. Matsuda,et al. 2′-C-Cyano-2′-deoxy-1-β-D-arabinofuranosylcytosine (CNDAC): A Mechanism-Based DNA-Strand-Breaking Antitumor Nucleoside1 , 1995 .
[18] W. Hong,et al. Synthesis and antitumor activity of a series of [2-substituted-4,5-bis(aminomethyl)-1,3-dioxolane]platinum(II) complexes. , 1994, Journal of medicinal chemistry.
[19] J. G. Cory,et al. 2'-Deoxy-2'-methylene derivatives of adenosine, guanosine, tubercidin, cytidine and uridine as inhibitors of L1210 cell growth in culture. , 1994, Biochemical pharmacology.
[20] C. Bolm,et al. Catalyzed Enantioselective Borane Reduction of Ketimine Derivatives , 1994 .
[21] N. Minakawa,et al. Nucleosides and nucleotides. 122. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine and its derivatives. A new class of nucleoside with a broad antitumor spectrum. , 1993, Journal of medicinal chemistry.
[22] R. Schinazi,et al. Deoxycytidine deaminase-resistant stereoisomer is the active form of (+/-)-2',3'-dideoxy-3'-thiacytidine in the inhibition of hepatitis B virus replication. , 1992, The Journal of biological chemistry.
[23] A. Matsuda,et al. Antitumor activity of a novel nucleoside, 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine (CNDAC) against murine and human tumors. , 1992, Cancer letters.
[24] L. J. Kurz,et al. 4'-Substituted nucleosides as inhibitors of HIV : an unusual oxetane derivative , 1992 .
[25] K. A. Walker,et al. Synthesis of 4′-cyanothymidine and analogs as potent inhibitors of HIV. , 1992 .
[26] D. Stemerick,et al. Stereospecific method to (E) and (Z) terminal fluoroolefins and its application to the synthesis of 2'-deoxy-2'-fluoromethylenenucleosides as potential inhibitors of ribonucleoside diphosphate reductase , 1991 .
[27] A. Matsuda,et al. Nucleosides and nucleotides. 100. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosyl-cytosine (CNDAC): design of a potential mechanism-based DNA-strand-breaking antineoplastic nucleoside. , 1991, Journal of medicinal chemistry.
[28] Y. Cheng,et al. Synthesis and anticancer and antiviral activities of various 2'- and 3'-methylidene-substituted nucleoside analogues and crystal structure of 2'-deoxy-2'-methylidenecytidine hydrochloride. , 1991, Journal of medicinal chemistry.
[29] J. Bollinger,et al. 2'-Deoxy-2'-methylenecytidine and 2'-deoxy-2',2'-difluorocytidine 5'-diphosphates: potent mechanism-based inhibitors of ribonucleotide reductase. , 1991, Journal of medicinal chemistry.
[30] A. Matsuda,et al. Antitumor activity of 2'-deoxy-2'-methylidenecytidine, a new 2'-deoxycytidine derivative. , 1991, Cancer research.
[31] A. Matsuda,et al. Nucleosides and nucleotides. 97. Synthesis of new broad spectrum antineoplastic nucleosides, 2'-deoxy-2'-methylidenecytidine (DMDC) and its derivatives. , 1991, Journal of medicinal chemistry.
[32] H. Mitsuya,et al. Molecular targets for AIDS therapy. , 1990, Science.
[33] E. Clercq. New acquisitions in the development of anti-HIV agents. , 1989 .
[34] R. Pauwels,et al. Anti-Hiv-1 Activity of 2′,3′-Dideoxinucleoside Analogues : Structure-Activity Relationship , 1989 .
[35] A. Matsuda,et al. Design, synthesis, and antineoplastic activity of 2'-deoxy-2'-methylidenecytidine. , 1988, Journal of medicinal chemistry.
[36] R. Schinazi,et al. Synthesis and antiviral activity of various 3'-azido analogues of pyrimidine deoxyribonucleosides against human immunodeficiency virus (HIV-1, HTLV-III/LAV). , 1988, Journal of medicinal chemistry.
[37] R. Schinazi,et al. Effect of combinations of acyclovir with vidarabine or its 5'-monophosphate on herpes simplex viruses in cell culture and in mice , 1982, Antimicrobial Agents and Chemotherapy.