Hydrophilic Flower‐Like CuS Superstructures as an Efficient 980 nm Laser‐Driven Photothermal Agent for Ablation of Cancer Cells

Photothermal ablation (PTA) therapy has attracted much interest in recent years as a minimally invasive alternative to conventional approaches, such as surgery and chemotherapy, for therapeutic intervention of specifi c biological targets. [ 1 , 2 ] In particular, near-infrared (NIR, λ = 700–1100 nm) laser-induced PTA, which converts NIR optical energy into thermal energy, has attracted increasing attention, because the NIR laser is absorbed less by biological tissues and the typical penetration depth of the NIR (such as 980 nm) light can be several centimeters in biological tissues. [ 3 , 4 ] A prerequisite for the development of the NIR laser-induced PTA is to gain access to biocompatible and effi cient photothermal coupling agents. As the well-known NIR photothermal conversion agents, gold (Au) nanostructures, including supramolecularly assembled nanoparticles, [ 5–8 ]

[1]  Kyung-Hwa Yoo,et al.  Multifunctional nanoparticles for combined doxorubicin and photothermal treatments. , 2009, ACS nano.

[2]  R. Stafford,et al.  Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[3]  D. Carroll,et al.  Increased Heating Efficiency and Selective Thermal Ablation of Malignant Tissue with DNA-Encased Multiwalled Carbon Nanotubes , 2009, ACS nano.

[4]  M. Hoepfner,et al.  Microscale Heat Transfer Transduced by Surface Plasmon Resonant Gold Nanoparticles. , 2007, The journal of physical chemistry. C, Nanomaterials and interfaces.

[5]  Erik C. Dreaden,et al.  Gold nanorod assisted near-infrared plasmonic photothermal therapy (PPTT) of squamous cell carcinoma in mice. , 2008, Cancer letters.

[6]  A. Usami Theoretical study of application of multiple scattering of light to a dye-sensitized nanocrystalline photoelectrichemical cell , 1997 .

[7]  Sun‐mi Lee,et al.  Synergistic Cancer Therapeutic Effects of Locally Delivered Drug and Heat Using Multifunctional Nanoparticles , 2010, Advanced materials.

[8]  Q. Gong,et al.  One-Pot Synthesis of Uniform Cu2O and CuS Hollow Spheres and Their Optical Limiting Properties , 2008 .

[9]  Younan Xia,et al.  Gold Nanocages: A Novel Class of Multifunctional Nanomaterials for Theranostic Applications , 2010, Advanced functional materials.

[10]  Christopher G. Rylander,et al.  Photothermal response of human and murine cancer cells to multiwalled carbon nanotubes after laser irradiation. , 2010, Cancer research.

[11]  K. Bartels,et al.  Photothermal effects on murine mammary tumors using indocyanine green and an 808-nm diode laser: an in vivo efficacy study. , 1996, Cancer letters.

[12]  Lisha Zhang,et al.  980‐nm Laser‐Driven Photovoltaic Cells Based on Rare‐Earth Up‐Converting Phosphors for Biomedical Applications , 2009 .

[13]  R. Nordquist,et al.  Laser-photosensitizer assisted immunotherapy: a novel modality for cancer treatment. , 1997, Cancer letters.

[14]  S. Torp-Pedersen,et al.  Interstitial hyperthermia of colorectal liver metastases with a US-guided Nd-YAG laser with a diffuser tip: a pilot clinical study. , 1993, Radiology.

[15]  J. West,et al.  Immunotargeted nanoshells for integrated cancer imaging and therapy. , 2005, Nano letters.

[16]  Wei Lu,et al.  Copper sulfide nanoparticles for photothermal ablation of tumor cells. , 2010, Nanomedicine.

[17]  Qiwei Tian,et al.  PEG-mediated solvothermal synthesis of NaYF4:Yb/Er superstructures with efficient upconversion luminescence , 2010 .

[18]  Sutapa Barua,et al.  Simultaneous enhancement of photothermal stability and gene delivery efficacy of gold nanorods using polyelectrolytes. , 2009, ACS nano.

[19]  Younan Xia,et al.  Gold nanocages as photothermal transducers for cancer treatment. , 2010, Small.

[20]  V. Zharov,et al.  Golden carbon nanotubes as multimodal photoacoustic and photothermal high-contrast molecular agents. , 2009, Nature nanotechnology.

[21]  Fan Zhang,et al.  Uniform nanostructured arrays of sodium rare-earth fluorides for highly efficient multicolor upconversion luminescence. , 2007, Angewandte Chemie.

[22]  Dong Liang,et al.  A chelator-free multifunctional [64Cu]CuS nanoparticle platform for simultaneous micro-PET/CT imaging and photothermal ablation therapy. , 2010, Journal of the American Chemical Society.

[23]  Wei Chen,et al.  Luminescence enhancement of EuS nanoclusters in zeolite , 2000 .

[24]  H. Dai,et al.  High performance in vivo near-IR (>1 μm) imaging and photothermal cancer therapy with carbon nanotubes , 2010, Nano research.

[25]  A. J. Frank,et al.  Standing wave enhancement of red absorbance and photocurrent in dye-sensitized titanium dioxide photoelectrodes coupled to photonic crystals. , 2003, Journal of the American Chemical Society.

[26]  Yang Li,et al.  Synthesis and characterization of tubular CuS with flower-like wall from a low temperature hydrothermal route , 2009 .

[27]  A. Vogel,et al.  Mechanisms of pulsed laser ablation of biological tissues. , 2003, Chemical reviews.

[28]  C. Rao,et al.  Hydrogel-assisted synthesis of nanotubes and nanorods of CdS, ZnS and CuS, showing some evidence for oriented attachment , 2006 .

[29]  Y. Jeong,et al.  A drug-loaded aptamer-gold nanoparticle bioconjugate for combined CT imaging and therapy of prostate cancer. , 2010, ACS nano.

[30]  Wei Lu,et al.  Targeted Photothermal Ablation of Murine Melanomas with Melanocyte-Stimulating Hormone Analog–Conjugated Hollow Gold Nanospheres , 2009, Clinical Cancer Research.

[31]  Wei Lu,et al.  Tumor Site–Specific Silencing ofNF-κB p65by Targeted Hollow Gold Nanosphere–Mediated Photothermal Transfection , 2010, Cancer Research.

[32]  J. Zee,et al.  Heating the patient: a promising approach? , 2002 .

[33]  T. Pal,et al.  Evolution of hierarchical hexagonal stacked plates of CuS from liquid-liquid interface and its photocatalytic application for oxidative degradation of different dyes under indoor lighting. , 2010, Environmental science & technology.

[34]  Wei-Yu Lin,et al.  Photothermal effects of supramolecularly assembled gold nanoparticles for the targeted treatment of cancer cells. , 2010, Angewandte Chemie.

[35]  Yiying Wu,et al.  Room-Temperature Ultraviolet Nanowire Nanolasers , 2001, Science.

[36]  Matteo Pasquali,et al.  Carbon nanotube‐enhanced thermal destruction of cancer cells in a noninvasive radiofrequency field , 2007, Cancer.