The MLH1 −93 G>A promoter polymorphism and genetic and epigenetic alterations in colon cancer
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C. Ulrich | R. Wolff | J. Potter | M. Slattery | K. Curtin | W. Samowitz | H. Albertsen | C. Sweeney | B. Caan
[1] Minoru Toyota,et al. Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer , 2007, Proceedings of the National Academy of Sciences.
[2] J. Knight,et al. MLH1 -93G>A promoter polymorphism and the risk of microsatellite-unstable colorectal cancer. , 2007, Journal of the National Cancer Institute.
[3] R. Houlston,et al. Re: MLH1 93G>A promoter polymorphism and the risk of microsatellite-unstable colorectal cancer. , 2007, Journal of the National Cancer Institute.
[4] W. Samowitz. The CpG island methylator phenotype in colorectal cancer. , 2007, Journal of Molecular Diagnostics.
[5] M. Loda,et al. Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample. , 2007, The Journal of molecular diagnostics : JMD.
[6] P. Goodfellow,et al. Evidence for heritable predisposition to epigenetic silencing of MLH1 , 2007, International journal of cancer.
[7] David I. K. Martin,et al. Inheritance of a cancer-associated MLH1 germ-line epimutation. , 2007, The New England journal of medicine.
[8] R. Wolff,et al. APC Mutations and Other Genetic and Epigenetic Changes in Colon Cancer , 2007, Molecular Cancer Research.
[9] R. Wolff,et al. Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer , 2007, International journal of cancer.
[10] Jennifer Herrick,et al. Association of smoking, CpG island methylator phenotype, and V600E BRAF mutations in colon cancer. , 2006, Journal of the National Cancer Institute.
[11] M. O'brien,et al. Comparison of Microsatellite Instability, CpG Island Methylation Phenotype, BRAF and KRAS Status in Serrated Polyps and Traditional Adenomas Indicates Separate Pathways to Distinct Colorectal Carcinoma End Points , 2006, The American journal of surgical pathology.
[12] E. Montgomery,et al. Sessile serrated adenomas with low- and high-grade dysplasia and early carcinomas: an immunohistochemical study of serrated lesions "caught in the act". , 2006, American journal of clinical pathology.
[13] P. Laird,et al. CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer , 2006, Nature Genetics.
[14] C. Ulrich,et al. Mismatch Repair Polymorphisms and Colorectal Polyps: hMLH1 −93G>A Variant Modifies Risk Associated with Smoking , 2006, The American Journal of Gastroenterology.
[15] M. Loda,et al. CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies , 2006, Gut.
[16] R. Wolff,et al. Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer. , 2005, Gastroenterology.
[17] P. Catalano,et al. Phenotype of Microsatellite-Stable Colorectal Carcinomas With CpG Island Methylation , 2005, The American journal of surgical pathology.
[18] L. Aaltonen,et al. Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status. , 2004, Human molecular genetics.
[19] N. Matsubara,et al. BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum , 2004, Gut.
[20] H. Swanson,et al. Dioxin-induced Immortalization of Normal Human Keratinocytes and Silencing of p53 and p16INK4a* , 2004, Journal of Biological Chemistry.
[21] C. Amos,et al. Association of the CpG island methylator phenotype with family history of cancer in patients with colorectal cancer. , 2003, Cancer research.
[22] Tsung-Teh Wu,et al. Frequent CpG island methylation in serrated adenomas of the colorectum. , 2003, The American journal of pathology.
[23] John D Potter,et al. Risk factors for hyperplastic and adenomatous polyps: evidence for malignant potential? , 2002, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[24] M. Leppert,et al. The colon cancer burden of genetically defined hereditary nonpolyposis colon cancer. , 2001, Gastroenterology.
[25] M. Leppert,et al. Microsatellite instability in sporadic colon cancer is associated with an improved prognosis at the population level. , 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[26] M. Leppert,et al. Inverse relationship between microsatellite instability and K-ras and p53 gene alterations in colon cancer. , 2001, The American journal of pathology.
[27] M. Leppert,et al. Associations between cigarette smoking, lifestyle factors, and microsatellite instability in colon tumors. , 2000, Journal of the National Cancer Institute.
[28] J. Herman,et al. CpG island methylator phenotype in colorectal cancer. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[29] G. Deng,et al. Methylation of CpG in a small region of the hMLH1 promoter invariably correlates with the absence of gene expression. , 1999, Cancer research.
[30] M. Leppert,et al. Alleles of APC modulate the frequency and classes of mutations that lead to colon polyps , 1998, Nature Genetics.
[31] S. Dertinger,et al. Influence of aromatic hydrocarbon receptor-mediated events on the genotoxicity of cigarette smoke condensate. , 1998, Carcinogenesis.
[32] S N Thibodeau,et al. Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability. , 1998, Cancer research.
[33] H T Lynch,et al. Hereditary Nonpolyposis Colorectal Cancer Patients Replication Errors in Benign and Malignant Tumors from , 2006 .
[34] Bert Vogelstein,et al. APC mutations occur early during colorectal tumorigenesis , 1992, Nature.
[35] J. Potter,et al. Estrogens reduce and withdrawal of estrogens increase risk of microsatellite instability-positive colon cancer. , 2001, Cancer research.
[36] T. Louis,et al. Colorectal adenomatous and hyperplastic polyps: smoking and N-acetyltransferase 2 polymorphisms. , 1999, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[37] J. Potter,et al. Energy balance and colon cancer--beyond physical activity. , 1997, Cancer research.
[38] T. Smyrk. Colon cancer connections. Cancer syndrome meets molecular biology meets histopathology. , 1994, The American journal of pathology.