Polymorphisms in ADAM33 are associated with allergic rhinitis due to Japanese cedar pollen

Background A recent report provided evidence that a disintegrin and metalloprotease domain 33 (ADAM33), a member of the ADAM family, is a novel susceptibility gene in asthma linked to bronchial hyper‐responsiveness. However, there has been no investigation of the genetic role of ADAM33 variants in nasal allergy.

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