Is pharmacokinetically guided chemotherapy dosage a better way forward?

[1]  S. Rodenhuis,et al.  Relationship between exposure and toxicity in high-dose chemotherapy with cyclophosphamide, thiotepa and carboplatin. , 2002, Annals of oncology : official journal of the European Society for Medical Oncology.

[2]  V. Gebski,et al.  Factors affecting epirubicin pharmacokinetics and toxicity: evidence against using body-surface area for dose calculation. , 1998, Journal of Clinical Oncology.

[3]  J. Peterse,et al.  Randomised trial of high-dose chemotherapy and haemopoietic progenitor-cell support in operable breast cancer with extensive axillary lymph-node involvement , 1998, The Lancet.

[4]  Terry L. Smith,et al.  Randomized trial of high-dose chemotherapy and blood cell autografts for high-risk primary breast carcinoma. , 2000, Journal of the National Cancer Institute.

[5]  M. Relling,et al.  Conventional compared with individualized chemotherapy for childhood acute lymphoblastic leukemia. , 1998, The New England journal of medicine.

[6]  D J Greenblatt,et al.  Pharmacokinetics and pharmacodynamics. , 1990, Hospital practice.

[7]  J. Bergh,et al.  Lack of relationship between systemic exposure for the component drug of the fluorouracil, epirubicin, and 4-hydroxycyclophosphamide regimen in breast cancer patients. , 1996, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[8]  J. Bergh,et al.  Tailored fluorouracil, epirubicin, and cyclophosphamide compared with marrow-supported high-dose chemotherapy as adjuvant treatment for high-risk breast cancer: a randomised trial , 2000, The Lancet.

[9]  H. Gurney,et al.  Dose calculation of anticancer drugs: a review of the current practice and introduction of an alternative. , 1996, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[10]  B. Teicher,et al.  A phase I-II study of cyclophosphamide, thiotepa, and carboplatin with autologous bone marrow transplantation in solid tumor patients. , 1990, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[11]  C J Hull,et al.  Pharmacokinetics and pharmacodynamics. , 1979, British journal of anaesthesia.