Multiple glomus tumors.

BACKGROUND Solitary and multiple glomus tumors are vascular tumors arising from glomus cells. These two forms have distinct clinical and histopathological features, suggesting that they might have a different pathogenesis. The multiple form is less frequent than the solitary form. Its diagnosis and treatment are more problematic and often delayed. MAIN OBSERVATION We present the case of a 40-year-old patient, with a 20-year history of numerous non-tender disseminated blue papules. At the age of 30 years one of the lesions was excised and than regrew and became painful. The histological exam of the lesions was consistent with glomangioma, also known as glomus tumor. We performed surgical resection of the nodular and painful lesions. CONCLUSION The diagnosis of glomus tumor is easily suspected when the lesion is painful located in the subungual region. However, if the lesions are multiple and extradigitally located, the clinical diagnosis may be difficult and requires having in mind this differential diagnosis. Our case also shows that glomus tumors may regrow after excision in the same location.

[1]  P. Amadio,et al.  Clinical Features of Multiple Glomus Tumors , 2008, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[2]  Paul J. L. Zhang,et al.  Intraosseous glomus tumor of the great toe: a case report with review of the literature. , 2008, The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons.

[3]  N. Taniguchi,et al.  An unusual case of a glomus tumor developing in a subcutaneous vein of the wrist , 2008, Journal of clinical ultrasound : JCU.

[4]  C. Hartnick,et al.  Case records of the Massachusetts General Hospital. Case 10-2008. A 10-year-old girl with dyspnea on exertion. , 2008, The New England journal of medicine.

[5]  Ritu Ghai,et al.  Pulmonary glomus tumor. , 2007, Annals of diagnostic pathology.

[6]  K. Kaga,et al.  Benign mass lesions deep inside the temporal bone: imaging diagnosis for proper management , 2007, Acta oto-laryngologica. Supplementum.

[7]  Á. Ramos Macías,et al.  [Glomus tumours of temporal bone origin. Study of 17 cases]. , 2007, Acta otorrinolaringologica espanola.

[8]  J. Stachura,et al.  Gastric solid glomus tumor and multiple glomangiomyomas of the large bowel with intravascular spread, multifocal perivascular proliferations and liver involvement. , 2007, Polish journal of pathology : official journal of the Polish Society of Pathologists.

[9]  P. Amadio,et al.  Extradigital glomus tumors: a 20-year experience. , 2006, Mayo Clinic proceedings.

[10]  I. Taştepe,et al.  Tracheal glomus tumor. , 2006, The Journal of thoracic and cardiovascular surgery.

[11]  M. Vikkula,et al.  Congenital plaque-type glomuvenous malformations presenting in childhood. , 2006, Archives of dermatology.

[12]  C. Fletcher,et al.  Intravascular glomus tumour: a previously undescribed phenomenon , 2005, Virchows Archiv A.

[13]  J. Mulliken,et al.  Glomuvenous malformation (glomangioma) and venous malformation: distinct clinicopathologic and genetic entities. , 2004, Archives of dermatology.

[14]  N. Cowley,et al.  Complete pain relief following treatment of a glomangiomyoma with the pulsed dye laser , 2003, Clinical and experimental dermatology.

[15]  L. Marinoni,et al.  Congenital Plaquelike Glomus Tumor in a Child , 2001, Pediatric dermatology.

[16]  A. Irrthum,et al.  Linkage disequilibrium narrows locus for venous malformation with glomus cells (VMGLOM) to a single 1.48 Mbp YAC , 2001, European Journal of Human Genetics.

[17]  P. J. Biggs,et al.  Glomus tumor in neural tissue. , 1996, The American Journal of dermatopathology.

[18]  R. Poppiti,et al.  Malignant glomus tumor. A case report of widespread metastases in a patient with multiple glomus body hamartomas. , 1996, The American journal of surgical pathology.

[19]  C. Fletcher,et al.  Cutaneous Intraneural Glomus Tumor , 1995, American journal of dermatopathology.

[20]  R. Siegle,et al.  Hypertonic saline destruction of multiple glomus tumors. , 1994, The Journal of dermatologic surgery and oncology.

[21]  E. P. Gould Sclerotherapy for multiple glomangiomata. , 1991, The Journal of dermatologic surgery and oncology.

[22]  D. Kamerer,et al.  Primary Fallopian Canal Glomus Tumors , 1990, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[23]  P. Masson Le glomus neuromyoarterial des regions tactiles et ses tumeurs , 1924 .