The clinical relevance of adrenomedullin: a promising profile?
暂无分享,去创建一个
[1] Y. Asada,et al. Immunohistochemical identification of adrenomedullin in human, rat, and porcine tissue , 1995, Histochemistry and Cell Biology.
[2] T. Asano,et al. Angiotensin II-induced insulin resistance is enhanced in adrenomedullin-deficient mice. , 2004, Endocrinology.
[3] C. Pan,et al. Relationship between contents of adrenomedullin and distributions of neutral endopeptidase in blood and tissues of rats in septic shock , 2004, Regulatory Peptides.
[4] C. Kumana,et al. Increased adrenomedullin expression in lungs in endotoxaemia. , 2004, The Journal of endocrinology.
[5] T. Horio,et al. Plasma adrenomedullin concentration is increased in patients with peripheral arterial occlusive disease associated with vascular inflammation , 2004, Regulatory Peptides.
[6] J. Reichen,et al. Vasodilator mRNA levels are increased in the livers of portal hypertensive NO‐synthase 3‐deficient mice , 2004, European journal of clinical investigation.
[7] S. Yildirim,et al. Relaxation effects of adrenomedullin in isolated rabbit corpus cavernosum smooth muscle , 2004, BJU international.
[8] Christophe Dussert,et al. Effects of adrenomedullin on endothelial cells in the multistep process of angiogenesis: Involvement of CRLR/RAMP2 and CRLR/RAMP3 receptors , 2004, International journal of cancer.
[9] N. Minamino,et al. The role of adrenomedullin and receptors in glomerular hyperfiltration in streptozotocin-induced diabetic rats. , 2004, Kidney international.
[10] C. Delaey,et al. INFLUENCE OF ADRENOMEDULLIN ON TONE OF ISOLATED BOVINE RETINAL ARTERIES.: PK.2 , 2004, Investigative ophthalmology & visual science.
[11] S. Miyano,et al. Identification of novel adrenomedullin in mammals: a potent cardiovascular and renal regulator , 2004, FEBS letters.
[12] L. Chao,et al. Adrenomedullin Protects Against Myocardial Apoptosis After Ischemia/Reperfusion Through Activation of Akt-GSK Signaling , 2004, Hypertension.
[13] N. Aiyar,et al. Calcitonin gene-related peptide receptor independently stimulates 3′,5′-cyclic adenosine monophosphate and Ca2+ signaling pathways , 1999, Molecular and Cellular Biochemistry.
[14] J. Bełtowski,et al. Adrenomedullin--what do we know 10 years since its discovery? , 2004, Polish journal of pharmacology.
[15] Y. Okada,et al. Hypoxia-Inducible Factor Regulates Survival of Antigen Receptor-Driven T Cells 1 , 2003, The Journal of Immunology.
[16] C. May,et al. Direct coronary vasodilator action of adrenomedullin is mediated by nitric oxide , 2003, British journal of pharmacology.
[17] K. Kitamura,et al. Plasma adrenomedullin is closely correlated with pulse wave velocity in middle-aged and elderly patients. , 2003, Hypertension research : official journal of the Japanese Society of Hypertension.
[18] R. Hurt,et al. Adrenomedullin is increased in the portal circulation during chronic sepsis in rats. , 2003, American journal of surgery.
[19] D. Smith,et al. CL/RAMP2 and CL/RAMP3 produce pharmacologically distinct adrenomedullin receptors: a comparison of effects of adrenomedullin22–52, CGRP8–37 and BIBN4096BS , 2003, British journal of pharmacology.
[20] L. Chao,et al. Adrenomedullin gene delivery attenuates myocardial infarction and apoptosis after ischemia and reperfusion. , 2003, American journal of physiology. Heart and circulatory physiology.
[21] S. K. Park,et al. Angiogenic role of adrenomedullin through activation of Akt, mitogen‐activated protein kinase, and focal adhesion kinase in endothelial cells , 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[22] D. Guidolin,et al. Vinblastine inhibits the angiogenic response induced by adrenomedullin in vitro and in vivo , 2003, Oncogene.
[23] Y. Nakashima,et al. Adrenomedullin inhibits pressure-induced mesangial MCP-1 expression through activation of protein kinase A. , 2003, Journal of nephrology.
[24] Renyi Wu,et al. Adrenomedullin-induced endothelium-dependent relaxation in porcine ciliary arteries. , 2003, Investigative ophthalmology & visual science.
[25] R. Quirion,et al. Adrenomedullin receptor binding sites in rat brain and peripheral tissues. , 2003, European journal of pharmacology.
[26] R. Bicknell,et al. The FASEB Journal express article 10.1096/fj.02-0993fje. Published online June 17, 2003. Transcriptional regulation of the CRLR gene in human microvascular endothelial cells by hypoxia , 2022 .
[27] E. Gabazza,et al. Increased oxidative stress is associated with elevated plasma levels of adrenomedullin in hypertensive patients with type 2 diabetes. , 2003, Diabetes care.
[28] J. Jhamandas,et al. Autonomic and neuroendocrine actions of adrenomedullin in the brain: mechanisms for homeostasis , 2003, Regulatory Peptides.
[29] Chao-shu Tang,et al. Roles of different peptide fragments derived from proadrenomedullin in the regulation of vascular tone in isolated rat aorta , 2003, Peptides.
[30] T. Ishimitsu,et al. Variations of human adrenomedullin gene and its relation to cardiovascular diseases. , 2003, Hypertension research : official journal of the Japanese Society of Hypertension.
[31] K. Kangawa,et al. Adrenomedullin infusion during ischemia/reperfusion attenuates left ventricular remodeling and myocardial fibrosis in rats. , 2003, Hypertension research : official journal of the Japanese Society of Hypertension.
[32] K. Kangawa,et al. Pulmonary vasodilator response to adrenomedullin in patients with pulmonary hypertension. , 2003, Hypertension research : official journal of the Japanese Society of Hypertension.
[33] T. Sakamoto,et al. Elevated Adrenomedullin in the Vitreous of Patients with Diabetic Retinopathy , 2003, Ophthalmologica.
[34] K. Nakao,et al. Adrenomedullin promotes proliferation and migration of cultured endothelial cells. , 2003, Hypertension research : official journal of the Japanese Society of Hypertension.
[35] K. Hatakeyama,et al. Immunohistological localization and possible functions of adrenomedullin. , 2003, Hypertension research : official journal of the Japanese Society of Hypertension.
[36] K. Kangawa,et al. Direct measurement of glycine-extended adrenomedullin in plasma and tissue using an ultrasensitive immune complex transfer enzyme immunoassay in rats. , 2003, Hypertension research : official journal of the Japanese Society of Hypertension.
[37] C. Packer,et al. Gender differences in pulmonary arterial reactivity to dilatory agonists in pulmonary hypertension. , 2003, The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia.
[38] B. Göke,et al. Calcitonin Receptor-Like Receptor Is Expressed on Gastrointestinal Immune Cells , 2003, Digestion.
[39] I. Chaudry,et al. Novel Approach to Prevent the Transition From the Hyperdynamic Phase to the Hypodynamic Phase of Sepsis: Role of Adrenomedullin and Adrenomedullin Binding Protein-1 , 2002, Annals of surgery.
[40] Kazuhiro Takahashi,et al. Elevated immunoreactive-adrenomedullin levels in the aqueous humor of patients with uveitis and vitreoretinal disorders , 2002, Peptides.
[41] G. Mcgregor,et al. Calcitonin receptor-like receptor: identification and distribution in human peripheral tissues , 2002, Cell and Tissue Research.
[42] M. Westphal,et al. Hemodynamic effects of exogenous adrenomedullin in healthy and endotoxemic sheep. , 2002, Biochemical and biophysical research communications.
[43] Y. Pang,et al. Effects of adrenomedullin on vascular calcification in rats , 2002, Zeitschrift für Kardiologie.
[44] N. Kobayashi,et al. Long-Term Adrenomedullin Infusion Improves Survival in Malignant Hypertensive Rats , 2002, Hypertension.
[45] Patrick M. Sexton,et al. International Union of Pharmacology. XXXII. The Mammalian Calcitonin Gene-Related Peptides, Adrenomedullin, Amylin, and Calcitonin Receptors , 2002, Pharmacological Reviews.
[46] J. Duarte,et al. Role of endothelium-derived relaxing factors in adrenomedullin-induced vasodilation in the rat kidney. , 2002, European journal of pharmacology.
[47] K. Kangawa,et al. Intravenous Adrenomedullin in Myocardial Function and Energy Metabolism in Patients After Myocardial Infarction , 2002, Journal of cardiovascular pharmacology.
[48] M. Santacana,et al. Adrenomedullin in the central nervous system , 2002, Microscopy research and technique.
[49] H. Kobayashi,et al. Cerebral Endothelial Cells are a Major Source of Adrenomedullin , 2002, Journal of neuroendocrinology.
[50] N. Brünner,et al. Neutralization of adrenomedullin inhibits the growth of human glioblastoma cell lines in vitro and suppresses tumor xenograft growth in vivo. , 2002, The American journal of pathology.
[51] N. Kobayashi,et al. Renoprotective Effect of Chronic Adrenomedullin Infusion in Dahl Salt-Sensitive Rats , 2002, Hypertension.
[52] T. Horio,et al. Possible involvement of oxidative stress in hypoxia-induced adrenomedullin secretion in cultured rat cardiomyocytes. , 2002, European journal of pharmacology.
[53] G. Mcgregor,et al. Expression and distribution of calcitonin receptor-like receptor in human hairy skin , 2002, Peptides.
[54] A. Kurtz,et al. Inflammatory Cytokines Stimulate Adrenomedullin Expression Through Nitric Oxide–Dependent and –Independent Pathways , 2002, Hypertension.
[55] J. Hyvelin,et al. Adrenomedullin: A Cardiac Depressant Factor in Septic Shock , 2001, Journal of cardiac surgery.
[56] U. Welsch,et al. Adrenomedullin in mammalian and human skin glands including the mammary gland. , 2002, Acta histochemica.
[57] S. Kato,et al. Adrenomedullin, an Endogenous Peptide, Counteracts Cardiovascular Damage , 2002, Circulation.
[58] J. Kato,et al. The Seven Amino Acids of Human RAMP2 (86) and RAMP3 (59) Are Critical for Agonist Binding to Human Adrenomedullin Receptors* , 2001, The Journal of Biological Chemistry.
[59] H. Kobayashi,et al. Adrenomedullin regulates blood–brain barrier functions in vitro , 2001, Neuroreport.
[60] L. Chao,et al. Human adrenomedullin gene delivery protects against cardiovascular remodeling and renal injury , 2001, Peptides.
[61] Tsutomu Takahashi,et al. Association of plasma adrenomedullin with carotid atherosclerosis in chronic ischemic stroke , 2001, Peptides.
[62] D. Hay,et al. Adrenomedullin receptors: molecular identity and function , 2001, Peptides.
[63] N. Parameswaran,et al. Cellular and molecular actions of adrenomedullin in glomerular mesangial cells , 2001, Peptides.
[64] H. Nishimatsu,et al. Vascular Abnormalities and Elevated Blood Pressure in Mice Lacking Adrenomedullin Gene , 2001, Circulation.
[65] J. Kato,et al. Effects of endothelin on adrenomedullin secretion and expression of adrenomedullin receptors in rat cardiomyocytes. , 2001, Biochemical and biophysical research communications.
[66] J. McMurray,et al. Effect of Neutral Endopeptidase Inhibition on the Actions of Adrenomedullin and Endothelin-1 in Resistance Arteries From Patients With Chronic Heart Failure , 2001, Hypertension.
[67] M. Petrie,et al. Effects of adrenomedullin on angiotensin II stimulated atrial natriuretic peptide and arginine vasopressin secretion in healthy humans. , 2001, British journal of clinical pharmacology.
[68] C. Yu,et al. Increase in plasma adrenomedullin in patients with heart failure characterised by diastolic dysfunction , 2001, Heart.
[69] J. McMurray,et al. Effect of adrenomedullin on the production of endothelin-1 and on its vasoconstrictor action in resistance arteries: evidence for a receptor-specific functional interaction in patients with heart failure , 2001 .
[70] R. Quirion,et al. Autoradiographic distribution of adrenomedullin receptors in the rat brain. , 2001, European journal of pharmacology.
[71] L. Chao,et al. Adrenomedullin gene delivery attenuates renal damage and cardiac hypertrophy in Goldblatt hypertensive rats. , 2001, American journal of physiology. Renal physiology.
[72] R. Fahlbusch,et al. Gene expression of adrenomedullin, leptin, their receptors and neuropeptide Y in hormone‐secreting and non‐functioning pituitary adenomas, meningiomas and malignant intracranial tumours in humans , 2001, Neuropathology and applied neurobiology.
[73] R. Doughty,et al. Plasma N-terminal pro-brain natriuretic peptide and adrenomedullin: prognostic utility and prediction of benefit from carvedilol in chronic ischemic left ventricular dysfunction. Australia-New Zealand Heart Failure Group. , 2001, Journal of the American College of Cardiology.
[74] P. Zipfel,et al. Complement Factor H Is a Serum-binding Protein for Adrenomedullin, and the Resulting Complex Modulates the Bioactivities of Both Partners* , 2001, The Journal of Biological Chemistry.
[75] Jing Shan,et al. Distribution of preproadrenomedullin mRNA in the rat central nervous system and its modulation by physiological stressors , 2001, The Journal of comparative neurology.
[76] N. Minamino,et al. Cardiac fibroblasts are major production and target cells of adrenomedullin in the heart in vitro. , 2001, Cardiovascular research.
[77] T. Fujita,et al. Hypoxic induction of adrenomedullin in cultured human umbilical vein endothelial cells , 2001, Journal of hypertension.
[78] T. Horio,et al. Alterations of Intrarenal Adrenomedullin and Its Receptor System in Heart Failure Rats , 2001, Hypertension.
[79] O. Smithies,et al. Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene. , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[80] H. Yagi,et al. Elevation of two molecular forms of adrenomedullin in plasma and urine in patients with acute myocardial infarction treated with early coronary angioplasty. , 2001, Clinical science.
[81] H. Miura,et al. Human coronary arteriolar dilation to adrenomedullin: role of nitric oxide and K(+) channels. , 2000, American journal of physiology. Heart and circulatory physiology.
[82] K. Kangawa,et al. Haemodynamic and hormonal effects of adrenomedullin in patients with pulmonary hypertension , 2000, Heart.
[83] C. Lazzeri,et al. Effects of low-dose adrenomedullin on cardiac function and systemic haemodynamics in man. , 2000, Clinical physiology.
[84] T. Dschietzig,et al. Adrenomedullin and myocardial contractility in the rat. , 2000, European journal of pharmacology.
[85] T. Eto,et al. Visualization of the Calcitonin Receptor-like Receptor and Its Receptor Activity-modifying Proteins during Internalization and Recycling* , 2000, The Journal of Biological Chemistry.
[86] I. Mackenzie,et al. Adrenomedullin is an autocrine regulator of endothelial growth in human endometrium. , 2000, Molecular human reproduction.
[87] L. Chao,et al. Human adrenomedullin gene delivery protects against cardiac hypertrophy, fibrosis, and renal damage in hypertensive dahl salt-sensitive rats. , 2000, Human gene therapy.
[88] K. Kangawa,et al. Comparison of intravenous adrenomedullin with atrial natriuretic peptide in patients with congestive heart failure. , 2000, The American journal of cardiology.
[89] N. Ali,et al. Activation of particulate guanylate cyclase by adrenomedullin in cultured SV-40 transformed cat iris sphincter smooth muscle (SV-CISM-2) cells. , 2000, Cellular signalling.
[90] H. Nishimatsu,et al. Adrenomedullin and nitric oxide inhibit human endothelial cell apoptosis via a cyclic GMP-independent mechanism. , 2000, Hypertension.
[91] M. Brunette,et al. The paradoxical effect of adrenomedullin on Na+ transport by the renal distal tubule luminal membrane , 2000, Molecular and Cellular Endocrinology.
[92] M. Young,et al. Factor H Binding to Bone Sialoprotein and Osteopontin Enables Tumor Cell Evasion of Complement-mediated Attack* , 2000, The Journal of Biological Chemistry.
[93] L. Edvinsson,et al. Positive inotropy mediated via CGRP receptors in isolated human myocardial trabeculae. , 2000, European journal of pharmacology.
[94] K. Takahashi,et al. Transcriptional control of adrenomedullin induction by phorbol ester in human monocytic leukemia cells. , 2000, European journal of biochemistry.
[95] Y. Yazaki,et al. Enhanced adrenomedullin production by mechanical stretching in cultured rat cardiomyocytes. , 2000, Hypertension.
[96] M. Komajda,et al. Plasma adrenomedullin, a new independent predictor of prognosis in patients with chronic heart failure. , 2000, European heart journal.
[97] M. Gassmann,et al. Hypoxia-inducible factor-1 (HIF-1) up-regulates adrenomedullin expression in human tumor cell lines during oxygen deprivation: a possible promotion mechanism of carcinogenesis. , 2000, Molecular endocrinology.
[98] T. Horio,et al. Cardiac adrenomedullin gene expression and peptide accumulation after acute myocardial infarction in rats. , 2000, American journal of physiology. Regulatory, integrative and comparative physiology.
[99] A. Richards,et al. Hemodynamic, hormonal, and renal effects of short-term adrenomedullin infusion in healthy volunteers. , 2000, The Journal of clinical endocrinology and metabolism.
[100] K. Okumura,et al. Plasma adrenomedullin levels in the coronary circulation in vasospastic angina pectoris. , 2000, The American journal of cardiology.
[101] U. Ikeda,et al. Positive inotropic effects of adrenomedullin on rat papillary muscle. , 2000, European journal of pharmacology.
[102] K. Kangawa,et al. Hemodynamic, renal, and hormonal effects of adrenomedullin infusion in patients with congestive heart failure. , 2000, Circulation.
[103] S. Nakamura,et al. Plasma adrenomedullin levels in patients with diabetes. , 2000, Diabetes care.
[104] A. Yndestad,et al. Induction of a myocardial adrenomedullin signaling system during ischemic heart failure in rats. , 2000, Circulation.
[105] M. Santacana,et al. Distribution of adrenomedullin-like immunoreactivity in the rat central nervous system by light and electron microscopy , 2000, Brain Research.
[106] P. Sexton,et al. Multiple ramp domains are required for generation of amylin receptor phenotype from the calcitonin receptor gene product. , 2000, Biochemical and biophysical research communications.
[107] J. McMurray,et al. Adrenomedullin selectively inhibits angiotensin II‐induced aldosterone secretion in humans , 2000, Journal of hypertension.
[108] R. Hancock,et al. Cationic antimicrobial peptides and their multifunctional role in the immune system. , 2000, Critical reviews in immunology.
[109] K. Inoki,et al. Regulation of rat mesangial cell migration by platelet-derived growth factor, angiotensin II, and adrenomedullin. , 1999, Journal of the American Society of Nephrology : JASN.
[110] G. Nussdorfer,et al. Structure–activity relationships of adrenomedullin in the circulation and adrenal gland , 1999, Regulatory Peptides.
[111] S. Kahl,et al. Adrenomedullin Binding Protein in the Plasma of Multiple Species: Characterization by Radioligand Blotting. , 1999, Endocrinology.
[112] Y. Asada,et al. Novel distribution of adrenomedullin-immunoreactive cells in human tissues , 1999, Histochemistry and Cell Biology.
[113] H. Kobayashi,et al. Cyclic AMP-dependent synthesis and release of adrenomedullin and proadrenomedullin N-terminal 20 peptide in cultured bovine adrenal chromaffin cells. , 1999, European journal of biochemistry.
[114] K. Takahashi,et al. Adrenomedullin in monocytes and macrophages: possible involvement of macrophage-derived adrenomedullin in atherogenesis. , 1999, Clinical science.
[115] M Morfis,et al. Multiple amylin receptors arise from receptor activity-modifying protein interaction with the calcitonin receptor gene product. , 1999, Molecular pharmacology.
[116] A. Richards,et al. Bioactivity and interactions of adrenomedullin and brain natriuretic peptide in patients with heart failure. , 1999, Hypertension.
[117] N. Minamino,et al. Increased plasma levels of adrenomedullin in patients with systemic inflammatory response syndrome. , 1999, American journal of respiratory and critical care medicine.
[118] W. Born,et al. A Receptor Activity Modifying Protein (RAMP)2-Dependent Adrenomedullin Receptor Is a Calcitonin Gene-Related Peptide Receptor when Coexpressed with Human RAMP1. , 1999, Endocrinology.
[119] Y. Koiwaya,et al. Secretion and clearance of the mature form of adrenomedullin in humans. , 1999, Life sciences.
[120] T. Fujita,et al. Hyperglycemia increases vascular adrenomedullin expression. , 1999, Biochemical and biophysical research communications.
[121] K. Kangawa,et al. Plasma adrenomedullin as an indicator of prognosis after acute myocardial infarction , 1999, Heart.
[122] M. Asakawa,et al. The RAMP2/CRLR complex is a functional adrenomedullin receptor in human endothelial and vascular smooth muscle cells , 1999, FEBS letters.
[123] R. Allaker,et al. An investigation into the antimicrobial effects of adrenomedullin on members of the skin, oral, respiratory tract and gut microflora. , 1999, FEMS immunology and medical microbiology.
[124] K. Kangawa,et al. An autocrine or a paracrine role of adrenomedullin in modulating cardiac fibroblast growth. , 1999, Cardiovascular research.
[125] T. Nagayama,et al. Effects of adrenomedullin and PAMP on adrenal catecholamine release in dogs. , 1999, American journal of physiology. Regulatory, integrative and comparative physiology.
[126] M. Oehler,et al. Regulation of endometrial angiogenesis. , 1999, Climacteric : the journal of the International Menopause Society.
[127] W. Burger,et al. Sulfonylureas and ischaemic preconditioning; a double-blind, placebo-controlled evaluation of glimepiride and glibenclamide. , 1999, European heart journal.
[128] J. Kato,et al. Differential hormonal profiles of adrenomedullin and proadrenomedullin n‐terminal 20 peptide in patients with heart failure and effect of treatment on their plasma levels , 1999, Clinical cardiology.
[129] N. Yokota,et al. Increased plasma levels of mature form of adrenomedullin in patients with chronic renal failure. , 1999, Clinical nephrology.
[130] T. Horio,et al. Cardiovascular and renal effects of adrenomedullin in rats with heart failure. , 1999, American journal of physiology. Regulatory, integrative and comparative physiology.
[131] R. Simari,et al. Autocrine role for the endothelin-B receptor in the secretion of adrenomedullin. , 1998, Hypertension.
[132] K. Kangawa,et al. cDNA CLONING OF CANINE ADRENOMEDULLIN AND ITS GENE EXPRESSION IN THE HEART AND BLOOD VESSELS IN ENDOTOXIN SHOCK , 1998, Shock.
[133] S. Vogel,et al. Induction of Adrenomedullin mRNA and Protein by Lipopolysaccharide and Paclitaxel (Taxol) in Murine Macrophages , 1998, Infection and Immunity.
[134] W. Claycomb,et al. Adrenomedullin Gene Expression Is Developmentally Regulated and Induced by Hypoxia in Rat Ventricular Cardiac Myocytes* , 1998, The Journal of Biological Chemistry.
[135] N. Minamino,et al. Production of Adrenomedullin in Macrophage Cell Line and Peritoneal Macrophage* , 1998, The Journal of Biological Chemistry.
[136] C. Pesquera,et al. Plasma Adrenomedullin Levels in Type 1 Diabetes: Relationship with clinical parameters , 1998, Diabetes Care.
[137] Melanie G. Lee,et al. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor , 1998, Nature.
[138] T. Nakamura,et al. Plasma adrenomedullin levels in patients with non-insulin dependent diabetes mellitus: close relationships with diabetic complications. , 1998, Endocrine journal.
[139] M. Weckström,et al. Evidence for cAMP-independent mechanisms mediating the effects of adrenomedullin, a new inotropic peptide. , 1998, Circulation.
[140] N. Minamino,et al. Adrenomedullin stimulates interleukin-6 production in Swiss 3T3 cells. , 1998, Biochemical and biophysical research communications.
[141] K. Kangawa,et al. The intermediate form of glycine-extended adrenomedullin is the major circulating molecular form in human plasma. , 1998, Biochemical and biophysical research communications.
[142] A. Richards,et al. Adrenomedullin(1-52) measured in human plasma by radioimmunoassay: plasma concentration, adsorption, and storage. , 1998, Clinical chemistry.
[143] N. Minamino,et al. Printed in U.S.A. Copyright © 1998 by The Endocrine Society Regulation of Adrenomedullin Production in Rat , 2022 .
[144] T. Ishimitsu,et al. Transcriptional regulation of human adrenomedullin gene in vascular endothelial cells. , 1998, Biochemical and biophysical research communications.
[145] K. Kangawa,et al. Plasma levels of adrenomedullin in patients with acute myocardial infarction. , 1998, Clinical science.
[146] Lyna Zhang,et al. PCR display identifies tamoxifen induction of the novel angiogenic factor adrenomedullin by a non estrogenic mechanism in the human endometrium , 1998, Oncogene.
[147] K. Kangawa,et al. Adrenomedullin: a possible autocrine or paracrine inhibitor of hypertrophy of cardiomyocytes. , 1998, Hypertension.
[148] C. Tortorella,et al. Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1998 by The Endocrine Society Proadrenomedullin N-Terminal 20 Peptide Inhibits Aldosterone Secretion of Human Adrenocortical and Conn’s Adenoma Cells: Comparison with Adrenomed , 2022 .
[149] J. Cockcroft,et al. Haemodynamic effects of adrenomedullin in human resistance and capacitance vessels. , 2003, British journal of clinical pharmacology.
[150] Kazuhiro Takahashi,et al. Expression of Adrenomedullin mRNA in the Human Brain and Pituitary , 1997, Peptides.
[151] Kazuhiro Takahashi,et al. Specific Adrenomedullin Binding Sites in the Human Brain , 1997, Peptides.
[152] Kazuhiro Takahashi,et al. Production and Secretion of Adrenomedullin From Glial Cell Tumors and its Effects on cAMP Production , 1997, Peptides.
[153] M. Nicholls,et al. Degradation of Human Adrenomedullin(1-52) by Plasma Membrane Enzymes and Identification of Metabolites , 1997, Peptides.
[154] Kazuhiro Takahashi,et al. Presence of Adrenomedullin-Like Immunoreactivity in the Human Cerebrospinal Fluid , 1997, Peptides.
[155] L. Chao,et al. Adrenomedullin gene delivery reduces blood pressure in spontaneously hypertensive rats. , 1997, Hypertension research : official journal of the Japanese Society of Hypertension.
[156] T. Moody,et al. Expression of Adrenomedullin and Its Receptor in Normal and Malignant Human Skin: A Potential Pluripotent Role in the Integument. , 1997, Endocrinology.
[157] T. Fujita,et al. Plasma adrenomedullin in diabetes , 1997, The Lancet.
[158] V. Miller,et al. Adrenomedullin-mediated relaxations in veins are endothelium-dependent and distinct from arteries. , 1997, Journal of cardiovascular pharmacology.
[159] D. Schocken,et al. Adrenomedullin, endothelin, neuropeptide Y, atrial, brain, and C-natriuretic prohormone peptides compared as early heart failure indicators. , 1997, Cardiovascular research.
[160] K. Ando,et al. A newly identified peptide, proadrenomedullin N-terminal 20 peptide, induces hypotensive action via pertussis toxin-sensitive mechanisms. , 1997, Hypertension.
[161] P. Little,et al. Metabolic ischemia in vascular smooth muscle causes adrenomedullin gene expression by a calcium dependent mechanism , 1997 .
[162] J. Grande,et al. Cytoprotective effects of adrenomedullin in glomerular cell injury: central role of cAMP signaling pathway. , 1997, Kidney international.
[163] M. Redfield,et al. Adrenomedullin in experimental congestive heart failure: cardiorenal activation. , 1997, The American journal of physiology.
[164] K. Kangawa,et al. Plasma concentrations of adrenomedullin correlate with the extent of pulmonary hypertension in patients with mitral stenosis , 1997, Heart.
[165] G. Cooper,et al. Beneficial hemodynamic and renal effects of adrenomedullin in an ovine model of heart failure. , 1997, Circulation.
[166] K. Kangawa,et al. Plasma adrenomedullin concentrations and cardiac and arterial hypertrophy in hypertension. , 1997, Hypertension.
[167] S. Barker,et al. Adrenomedullin acts as a local mediator of vascular homeostasis through interactions which lead to reduced endothelin-1 synthesis and secretion , 1997, Journal of Human Hypertension.
[168] M. Mathai,et al. Vasodilation and glomerular binding of adrenomedullin in rabbit kidney are not CGRP receptor mediated. , 1997, The American journal of physiology.
[169] M. Gassmann,et al. Oxygen(es) and the hypoxia-inducible factor-1. , 1997, Biological chemistry.
[170] A. Ferguson,et al. Adrenomedullin microinjection into the area postrema increases blood pressure. , 1997, The American journal of physiology.
[171] F. Marumo,et al. Microlocalization and effects of adrenomedullin in nephron segments and in mesangial cells of the rat. , 1997, The American journal of physiology.
[172] N. Minamino,et al. Increased plasma concentrations of adrenomedullin correlate with relaxation of vascular tone in patients with septic shock. , 1997, Critical care medicine.
[173] G. Cooper,et al. Hemodynamic, hormonal, and renal effects of adrenomedullin in conscious sheep. , 1997, The American journal of physiology.
[174] K. Sunagawa,et al. Vasodilator effects of adrenomedullin on small pulmonary arteries and veins in anaesthetized cats , 1997, British journal of pharmacology.
[175] O. Vuolteenaho,et al. Adrenomedullin Gene Expression in the Rat Heart is Stimulated by Acute Pressure Overload: Blunted Effect in Experimental Hypertension. , 1997, Endocrinology.
[176] N. Tamura,et al. Shear stress augments expression of C-type natriuretic peptide and adrenomedullin. , 1997, Hypertension.
[177] J. Yoshikawa,et al. Adrenomedullin is a potent inhibitor of angiotensin II-induced migration of human coronary artery smooth muscle cells. , 1997, Hypertension.
[178] M. Shichiri,et al. Adrenomedullin as an autocrine/paracrine apoptosis survival factor for rat endothelial cells. , 1997, Endocrinology.
[179] K. Kangawa,et al. Negative inotropic effect of adrenomedullin in isolated adult rabbit cardiac ventricular myocytes. , 1997, Circulation.
[180] G. Cooper,et al. Adrenomedullin: a hypotensive hormone in man. , 1997, Clinical science.
[181] K. Kangawa,et al. Production of adrenomedullin in human vascular endothelial cells. , 1997, Life sciences.
[182] L. Malendowicz,et al. Effects of adrenomedullin on the human adrenal glands: an in vitro study. , 1997, The Journal of clinical endocrinology and metabolism.
[183] N. Arakawa,et al. Potent and long-lasting vasodilatory effects of adrenomedullin in humans. Comparisons between normal subjects and patients with chronic heart failure. , 1997, Circulation.
[184] K. Kangawa,et al. HYPOTENSIVE EFFECT OF CHRONICALLY INFUSED ADRENOMEDULLIN IN CONSCIOUS WISTAR‐KYOTO AND SPONTANEOUSLY HYPERTENSIVE RATS , 1997, Clinical and Experimental Pharmacology and Physiology.
[185] J. Burnett,et al. Role of prostaglandins and renal nerves in the renal actions of adrenomedullin. , 1997, The American journal of physiology.
[186] Y. Wei,et al. [Effect of adrenomedullin on mesenteric microvessels and microlymphatics in rat]. , 1997, Sheng li xue bao : [Acta physiologica Sinica].
[187] B. Canny,et al. Adrenomedullin stimulates cAMP accumulation and inhibits atrial natriuretic peptide gene expression in cardiomyocytes. , 1997, Biochemical and biophysical research communications.
[188] S. Bloom,et al. Circulating adrenomedullin does not regulate systemic blood pressure but increases plasma prolactin after intravenous infusion in humans: a pharmacokinetic study. , 1997, The Journal of clinical endocrinology and metabolism.
[189] D. Heistad,et al. Mechanisms of adrenomedullin-induced dilatation of cerebral arterioles. , 1997, Stroke.
[190] K. Kangawa,et al. Mechanism of adrenomedullin-induced relaxation in isolated canine retinal arteries. , 1997, Investigative ophthalmology & visual science.
[191] H. Champion,et al. Adrenomedullin-(22-52) antagonizes vasodilator responses to CGRP but not adrenomedullin in the cat. , 1997, The American journal of physiology.
[192] K. Kangawa,et al. Plasma proadrenomedullin N-terminal 20 peptide (PAMP) in patients with congestive heart failure. , 1997, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
[193] B. Cheung,et al. Elevated plasma levels of human adrenomedullin in cardiovascular, respiratory, hepatic and renal disorders. , 1997, Clinical science.
[194] U. Ikeda,et al. Adrenomedullin augments inducible nitric oxide synthase expression in cytokine-stimulated cardiac myocytes. , 1996, Circulation.
[195] S. Kapas,et al. Actions of adrenomedullin on the rat adrenal cortex. , 1996, Endocrine research.
[196] A. Bishop,et al. Effect of human adrenomedullin on a canine tibial perfusion model in the absence of vascular endothelium , 1996, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[197] Frank Cuttitta,et al. Adrenomedullin Expression in Human Tumor Cell Lines ITS POTENTIAL ROLE AS AN AUTOCRINE GROWTH FACTOR* , 1996, The Journal of Biological Chemistry.
[198] H. Arima,et al. Intracerebroventricular injection of adrenomedullin inhibits vasopressin release in conscious rats , 1996, Neuroscience Letters.
[199] J. Mehta,et al. Adrenomedullin dilates rat pulmonary artery rings during hypoxia: role of nitric oxide and vasodilator prostaglandins. , 1996, Journal of cardiovascular pharmacology.
[200] K. Kitamura,et al. Inhibition of aldosterone production by adrenomedullin, a hypotensive peptide, in the rat. , 1996, Hypertension.
[201] D. Schocken,et al. Atrial natriuretic peptide increases adrenomedullin in the circulation of healthy humans. , 1996, Life sciences.
[202] U. Ikeda,et al. Adrenomedullin increases inducible nitric oxide synthase in rat vascular smooth muscle cells stimulated with interleukin-1. , 1996, Hypertension.
[203] T. Moody,et al. Regulation of insulin secretion and blood glucose metabolism by adrenomedullin. , 1996, Endocrinology.
[204] R. Rodeheffer,et al. Cardiac secretion of adrenomedullin in human heart failure. , 1996, The Journal of clinical investigation.
[205] K. Kangawa,et al. Nitric oxide‐associated relaxing effects of adrenomedullin in rat aorta , 1996 .
[206] Y. Koiwaya,et al. Increased plasma adrenomedullin levels in chronic congestive heart failure. , 1996, American heart journal.
[207] A. Kaye,et al. Pulmonary vasodilator responses to adrenomedullin are reduced by NOS inhibitors in rats but not in cats. , 1996, The American journal of physiology.
[208] Y. Hattori,et al. Up-regulation of rat adrenomedullin gene expression by endotoxin: relation to nitric oxide synthesis. , 1996, Life sciences.
[209] Y. Hirata,et al. Increased circulating adrenomedullin, a novel vasodilatory peptide, in sepsis. , 1996, The Journal of clinical endocrinology and metabolism.
[210] Y. Koiwaya,et al. Increased plasma adrenomedullin in acute myocardial infarction. , 1996, American heart journal.
[211] T. Horio,et al. Interaction of adrenomedullin and platelet-derived growth factor on rat mesangial cell production of endothelin. , 1996, Hypertension.
[212] G. Mazzocchi,et al. Adrenomedullin and calcitonin gene-related peptide inhibit aldosterone secretion in rats, acting via a common receptor. , 1996, Life sciences.
[213] W. Samson,et al. Renal Effects of Adrenomedullin in the Rat , 1996, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.
[214] H. Ruskoaho,et al. Inotropic effect of adrenomedullin in the isolated perfused rat heart. , 1996, Acta physiologica Scandinavica.
[215] J. Yoshikawa,et al. Adrenomedullin as a novel antiproliferative factor of vascular smooth muscle cells , 1996, Journal of hypertension.
[216] Kazuhiro Takahashi,et al. Immunocytochemical localization of adrenomedullin-like immunoreactivity in the human hypothalamus and the adrenal gland , 1996, Neuroscience Letters.
[217] K. Kangawa,et al. Plasma adrenomedullin concentration in patients with heart failure. , 1996, The Journal of clinical endocrinology and metabolism.
[218] L. Navar,et al. Renal responses to intra-arterial administration of adrenomedullin in dogs. , 1996, The American journal of physiology.
[219] J. Yoshikawa,et al. Plasma adrenomedullin concentrations in essential hypertension. , 1996, Hypertension.
[220] A. Shigematsu,et al. Inhibitory effect of adrenomedullin on rat mesangial cell mitogenesis. , 1996, Nephron.
[221] R. Muff,et al. Adrenomedullin and calcitonin gene-related peptide interact with the same receptor in cultured human neuroblastoma SK-N-MC cells , 1995, Peptides.
[222] Y. Ueta,et al. Adrenomedullin-immunoreactive neurons in the paraventricular and supraoptic nuclei of the rat , 1995, Neuroscience Letters.
[223] N. Aiyar,et al. Discovery of adrenomedullin in rat ischemic cortex and evidence for its role in exacerbating focal brain ischemic damage. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[224] C. May,et al. ACTH‐Suppressive and Vasodilator Actions of Adrenomedullin in Conscious Sheep , 1995, Journal of neuroendocrinology.
[225] T. Ishimitsu,et al. Increased plasma levels of adrenomedullin in patients with heart failure. , 1995, Journal of the American College of Cardiology.
[226] M. Fujishima,et al. Cardiovascular and neurohormonal effects of intravenous adrenomedullin in conscious rabbits. , 1995, The American journal of physiology.
[227] K. Catt,et al. Cloning and Expression of cDNA Encoding a Rat Adrenomedullin Receptor (*) , 1995, The Journal of Biological Chemistry.
[228] J. Grande,et al. Adrenomedullin suppresses mitogenesis in rat mesangial cells via cAMP pathway. , 1995, Biochemical and biophysical research communications.
[229] N. Minamino,et al. Endotoxin markedly elevates plasma concentration and gene transcription of adrenomedullin in rat. , 1995, Biochemical and biophysical research communications.
[230] T. Horio,et al. Adrenomedullin as a novel antimigration factor of vascular smooth muscle cells. , 1995, Circulation research.
[231] K. Sugita,et al. Effects of Adrenomedullin, Calcitonin Gene-Related Peptide, and Amylin on Cerebral Circulation in Dogs , 1995, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[232] O. Kida,et al. HAEMODYNAMIC RESPONSES TO RAT ADRENOMEDULLIN IN ANAESTHETIZED SPONTANEOUSLY HYPERTENSIVE RATS , 1995, Clinical and experimental pharmacology & physiology.
[233] J. Siegfried,et al. Expression of adrenomedullin in normal human lung and in pulmonary tumors. , 1995, Endocrinology.
[234] N. Minamino,et al. Effects of vasoactive substances and cAMP related compounds on adrenomedullin production in cultured vascular smooth muscle cells , 1995, FEBS letters.
[235] J. Burnett,et al. Elevation of circulating and ventricular adrenomedullin in human congestive heart failure. , 1995, Circulation.
[236] Y. Kureishi,et al. Adrenomedullin decreases both cytosolic Ca2+ concentration and Ca(2+)-sensitivity in pig coronary arterial smooth muscle. , 1995, Biochemical and biophysical research communications.
[237] H. Lippton,et al. Vasodilator effect of human adrenomedullin(13-52) on hypertensive rats. , 1995, Canadian journal of physiology and pharmacology.
[238] W. Born,et al. Receptors for calcitonin, calcitonin gene related peptide, amylin, and adrenomedullin. , 1995, Canadian journal of physiology and pharmacology.
[239] A. Cadieux,et al. Rat adrenomedullin induces a selective arterial vasodilation via CGRP1 receptors in the double-perfused mesenteric bed of the rat. , 1995, Canadian journal of physiology and pharmacology.
[240] K. Hirata,et al. Adrenomedullin inhibits the secretion of cytokine-induced neutrophil chemoattractant, a member of the interleukin-8 family, from rat alveolar macrophages. , 1995, Biochemical and biophysical research communications.
[241] F. Marumo,et al. Characterization of immunoreactive adrenomedullin in human plasma and urine. , 1995, Life sciences.
[242] T. Horio,et al. Inhibition of endothelin production by adrenomedullin in vascular smooth muscle cells. , 1995, Hypertension.
[243] W. Samson,et al. The novel vasoactive hormone, adrenomedullin, inhibits water drinking in the rat. , 1995, Endocrinology.
[244] K. Takahashi,et al. Adrenomedullin in human brain, adrenal glands and tumor tissues of pheochromocytoma, ganglioneuroblastoma and neuroblastoma. , 1995, The Journal of clinical endocrinology and metabolism.
[245] D. Smith,et al. An abundant and specific binding site for the novel vasodilator adrenomedullin in the rat. , 1995, Endocrinology.
[246] W. Samson,et al. A novel vasoactive peptide, adrenomedullin, inhibits pituitary adrenocorticotropin release. , 1995, Endocrinology.
[247] K. Kangawa,et al. Receptors for adrenomedullin in human vascular endothelial cells. , 1995, European journal of pharmacology.
[248] J. Burnett,et al. Renal localization and actions of adrenomedullin: a natriuretic peptide. , 1995, The American journal of physiology.
[249] Y. Kambayashi,et al. Adrenomedullin Stimulates Two Signal Transduction Pathways, cAMP Accumulation and Ca2+ Mobilization, in Bovine Aortic Endothelial Cells (*) , 1995, The Journal of Biological Chemistry.
[250] T. Tamaki,et al. Effects of a synthetic rat adrenomedullin on regional hemodynamics in rats. , 1995, European journal of pharmacology.
[251] N. Minamino,et al. Interleukin-1, tumor necrosis factor and lipopolysaccharide additively stimulate production of adrenomedullin in vascular smooth muscle cells. , 1995, Biochemical and biophysical research communications.
[252] S. Gardiner,et al. Regional haemodynamic effects of human and rat adrenomedullin in conscious rats , 1995, British journal of pharmacology.
[253] H. Lippton,et al. Interaction of human adrenomedullin 13–52 with calcitonin gene‐related peptide receptors in the microvasculature of the rat and hamster , 1995, British journal of pharmacology.
[254] H. Champion,et al. Comparison of responses to adrenomedullin and adrenomedullin analogs in the mesenteric vascular bed of the cat. , 1995, European journal of pharmacology.
[255] T. Yamaguchi,et al. Effect of adrenomedullin on aldosterone secretion by dispersed rat adrenal zona glomerulosa cells. , 1994, Life sciences.
[256] B. Nossaman,et al. Comparative effects of adrenomedullin, an adrenomedullin analog, and CGRP in the pulmonary vascular bed of the cat and rat. , 1994, Life sciences.
[257] T. Ishimitsu,et al. Plasma levels of adrenomedullin, a newly identified hypotensive peptide, in patients with hypertension and renal failure. , 1994, The Journal of clinical investigation.
[258] T. Ishimitsu,et al. Clinical studies on the sites of production and clearance of circulating adrenomedullin in human subjects. , 1994, Hypertension.
[259] Shokei Kim,et al. Effect of adrenomedullin on renal hemodynamics and functions in dogs. , 1994, European journal of pharmacology.
[260] N. Minamino,et al. Production and secretion of adrenomedullin from vascular smooth muscle cells: augmented production by tumor necrosis factor-alpha. , 1994, Biochemical and biophysical research communications.
[261] T. Ishimitsu,et al. Genomic structure of human adrenomedullin gene. , 1994, Biochemical and biophysical research communications.
[262] N. Minamino,et al. Identification and hypotensive activity of proadrenomedullin N‐terminal 20 peptide (PAMP) , 1994, FEBS letters.
[263] K. Miyamoto,et al. Endothelial cells actively synthesize and secrete adrenomedullin. , 1994, Biochemical and biophysical research communications.
[264] Y. Komiyama,et al. Centrally induced vasopressor and sympathetic responses to a novel endogenous peptide, adrenomedullin, in anesthetized rats. , 1994, American journal of hypertension.
[265] W. Summer,et al. Adrenomedullin dilates the pulmonary vascular bed in vivo. , 1994, Journal of applied physiology.
[266] N. Minamino,et al. Adrenomedullin stimulates cyclic AMP formation in rat vascular smooth muscle cells. , 1994, Biochemical and biophysical research communications.
[267] K. Kangawa,et al. Immunoreactive adrenomedullin in human plasma , 1994, FEBS letters.
[268] F. Marumo,et al. Specific receptors for adrenomedullin in cultured rat vascular smooth muscle cells , 1994, FEBS letters.
[269] K. Kangawa,et al. Complete amino acid sequence of porcine adrenomedullin and cloning of cDNA encoding its precursor , 1994, FEBS letters.
[270] K. Kangawa,et al. Distribution and characterization of immunoreactive adrenomedullin in human tissue and plasma , 1994, FEBS letters.
[271] A. Kaye,et al. L-NAME modulates responses to adrenomedullin in the hindquarters vascular bed of the rat. , 1994, Life sciences.
[272] P. Kadowitz,et al. Synthetic human adrenomedullin and ADM15-52 have potent short-lasting vasodilator activity in the pulmonary vascular bed of the cat. , 1994, Life sciences.
[273] K. Kangawa,et al. Vasodilator effect of adrenomedullin and calcitonin gene-related peptide receptors in rat mesenteric vascular beds. , 1993, Biochemical and biophysical research communications.
[274] K. Kangawa,et al. Molecular cloning and biological activities of rat adrenomedullin, a hypotensive peptide. , 1993, Biochemical and biophysical research communications.
[275] K. Kangawa,et al. Hemodynamic effects of a novel hypotensive peptide, human adrenomedullin, in rats. , 1993, European journal of pharmacology.
[276] K. Kangawa,et al. Cloning and characterization of cDNA encoding a precursor for human adrenomedullin. , 1993, Biochemical and biophysical research communications.
[277] K. Kangawa,et al. Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. , 1993, Biochemical and biophysical research communications.
[278] W. Summer,et al. The effect of adrenomedullin on the isolated heart. , 1993, Life sciences.
[279] D. Poyner. Calcitonin gene-related peptide: multiple actions, multiple receptors. , 1992, Pharmacology & therapeutics.
[280] S. Moncada,et al. Nitric oxide: physiology, pathophysiology, and pharmacology. , 1991, Pharmacological reviews.
[281] M. Fukase,et al. Calcitonin gene-related peptide receptor antagonist human CGRP-(8-37). , 1989, The American journal of physiology.
[282] Sadao Kimura,et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells , 1988, Nature.
[283] M. Karin,et al. Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP , 1987, Cell.