Imaging in Neovascular Age-Related Macular Degeneration

Imaging plays an essential role in the diagnosis and treatment of age-related macular degeneration (AMD). This review describes the imaging modalities most commonly employed by ophthalmologists caring for patients with neovascular AMD. Imaging modalities discussed include fluorescein angiography, optical coherence tomography, indocyanine green angiography, and fundus autofluorescence.

[1]  Joan W. Miller,et al.  Reproducibility of retinal thickness measurements on normal and pathologic eyes by different optical coherence tomography instruments. , 2010, American journal of ophthalmology.

[2]  K Bailey Freund,et al.  Outer retinal tubulation: a novel optical coherence tomography finding. , 2009, Archives of ophthalmology.

[3]  Amitha Domalpally,et al.  QUALITY ISSUES IN INTERPRETATION OF OPTICAL COHERENCE TOMOGRAMS IN MACULAR DISEASES , 2009, Retina.

[4]  S. Schwartz,et al.  Age-related macular degeneration: experimental and emerging treatments , 2009, Clinical ophthalmology.

[5]  A. Bird,et al.  FUNDUS AUTOFLUORESCENCE IMAGING: Review and Perspectives , 2008, Retina.

[6]  C. Regillo,et al.  Anti-VEGF agents in the treatment of neovascular age-related macular degeneration: applying clinical trial results to the treatment of everyday patients. , 2007, American journal of ophthalmology.

[7]  Anat Loewenstein,et al.  Retinal pigment epithelial detachment. , 2007, Survey of ophthalmology.

[8]  M. Mandai,et al.  Polypoidal choroidal vasculopathy with choroidal vascular hyperpermeability. , 2006, American journal of ophthalmology.

[9]  N. Bressler,et al.  Chapter 61 – Neovascular (Exudative) Age-Related Macular Degeneration , 2005 .

[10]  Richard F Spaide,et al.  COMPARISON OF FLUORESCEIN ANGIOGRAPHY AND OPTICAL COHERENCE TOMOGRAPHY FOR PATIENTS WITH CHOROIDAL NEOVASCULARIZATION AFTER PHOTODYNAMIC THERAPY , 2005, Retina.

[11]  W. Brannath,et al.  Optical coherence tomography guided retreatment of photodynamic therapy , 2005, British Journal of Ophthalmology.

[12]  S. J. Talks,et al.  Correlation of optical coherence tomography, with or without additional colour fundus photography, with stereo fundus fluorescein angiography in diagnosing choroidal neovascular membranes , 2005, British Journal of Ophthalmology.

[13]  F. Roudot-thoraval,et al.  Clinical features of drusenoid pigment epithelial detachment in age related macular degeneration , 2004, British Journal of Ophthalmology.

[14]  Michael D. Ober,et al.  Ophthalmic fundus imaging: today and beyond. , 2004, American journal of ophthalmology.

[15]  S. C. Lee,et al.  Choroidal neovascularization characteristics and its size in optical coherence tomography. , 2003, Yonsei medical journal.

[16]  J. Jonas.  VERTEPORFIN THERAPY OF SUBFOVEAL CHOROIDAL NEOVASCULARIZATION IN AGE-RELATED MACULAR DEGENERATION: Meta-Analysis of 2-Year Safety Results in Three Randomized Clinical Trials: Treatment of Age-Related Macular Degeneration with Photodynamic Therapy and Verteporfin in Photodynamic Therapy Study Report , 2002, American journal of ophthalmology.

[17]  J. Slakter,et al.  RETINAL ANGIOMATOUS PROLIFERATION IN AGE–RELATED MACULAR DEGENERATION , 2001, Retina.

[18]  C Bellman,et al.  Fundus autofluorescence and development of geographic atrophy in age-related macular degeneration. , 2001, Investigative ophthalmology & visual science.

[19]  T. Stokkermans,et al.  Treatment of age-related macular degeneration. , 2000, Clinical eye and vision care.

[20]  J. Ceuppens,et al.  HYPOTENSIVE SHOCK AS A COMPLICATION OF INFRACYANINE GREEN INJECTION , 1998, Retina.

[21]  Flower Rw,et al.  Disparity between fundus camera and scanning laser ophthalmoscope indocyanine green imaging of retinal pigment epithelium detachments. , 1998 .

[22]  C S Yang,et al.  Digital indocyanine green angiography in chorioretinal diseases. , 1995, Zhonghua yi xue za zhi = Chinese medical journal; Free China ed.

[23]  E. Gaillard,et al.  PHOTOPHYSICAL STUDIES ON HUMAN RETINAL LIPOFUSCIN , 1995, Photochemistry and photobiology.

[24]  R P Murphy,et al.  Frequency of adverse systemic reactions after fluorescein angiography. Results of a prospective study. , 1991, Ophthalmology.

[25]  J. Weiter,et al.  Cell loss in the aging retina. Relationship to lipofuscin accumulation and macular degeneration. , 1989, Investigative ophthalmology & visual science.

[26]  Steffen Schmitz-Valckenberg,et al.  Fundus autofluorescence and progression of age-related macular degeneration. , 2009, Survey of ophthalmology.

[27]  Andrea Hassenstein,et al.  Clinical use and research applications of Heidelberg retinal angiography and spectral‐domain optical coherence tomography – a review , 2009, Clinical & experimental ophthalmology.

[28]  William J Feuer,et al.  An optical coherence tomography-guided, variable dosing regimen with intravitreal ranibizumab (Lucentis) for neovascular age-related macular degeneration. , 2007, American journal of ophthalmology.

[29]  M. M. Ballús,et al.  Indocyanine green angiography in chorioretinal diseases: indications and interpretation , 2003 .

[30]  Jennifer I. Lim,et al.  Indocyanine green angiography in chorioretinal diseases: indications and interpretation: an evidence-based update. , 2003, Ophthalmology.

[31]  Neil M Bressler,et al.  Verteporfin therapy of subfoveal choroidal neovascularization in age-related macular degeneration: two-year results of a randomized clinical trial including lesions with occult with no classic choroidal neovascularization-verteporfin in photodynamic therapy report 2. , 2002, American journal of ophthalmology.

[32]  N. Bressler,et al.  Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: one-year results of 2 randomized clinical trials--TAP report. Treatment of age-related macular degeneration with photodynamic therapy (TAP) Study Group. , 1999, Archives of ophthalmology.

[33]  J. Lim,et al.  Anaphylactic shock following indocyanine green angiography. , 1996, Archives of ophthalmology.

[34]  E S Gragoudas,et al.  Adverse reactions due to indocyanine green. , 1994, Ophthalmology.

[35]  L A Yannuzzi,et al.  IDIOPATHIC POLYPOIDAL CHOROIDAL VASCULOPATHY (IPCV) , 1990, Retina.

[36]  J. Weiter,et al.  CELL LOSS IN THE AGING RETINA , 1989 .