论文信息 - p38 MAP kinase inhibitors. Part 3: SAR on 3,4-dihydropyrimido[4,5-d]pyrimidin-2-ones and 3,4-dihydropyrido[4,3-d]pyrimidin-2-ones. - 字舞流文

p38 MAP kinase inhibitors. Part 3: SAR on 3,4-dihydropyrimido[4,5-d]pyrimidin-2-ones and 3,4-dihydropyrido[4,3-d]pyrimidin-2-ones.

S. O'keefe | S. Natarajan | James E. Thompson | E. O’neill | David D. Wisnoski

[1] D. Zaller,et al. Structural basis for p38α MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity , 2003, Nature Structural Biology.

[2] D. Zaller,et al. Structural basis for p38alpha MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity. , 2003 .

[3] D. Zaller,et al. Design and synthesis of potent, orally bioavailable dihydroquinazolinone inhibitors of p38 MAP kinase. , 2003, Bioorganic & medicinal chemistry letters.

[4] D. Zaller,et al. p38MAP kinase inhibitors. Part 1: design and development of a new class of potent and highly selective inhibitors based on 3,4-dihydropyrido[3,2-d]pyrimidone scaffold. , 2003, Bioorganic & medicinal chemistry letters.

[5] G. F. Hawkins,et al. The preparation of 5-fluoronicotinic acid and 5-fluoronicotinamide. , 1949, The Journal of organic chemistry.