Advancing mammalian cell culture engineering using genome-scale technologies.
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Timothy J Griffin | Wei-Shou Hu | Hongwei Xie | Gargi Seth | T. Griffin | Hongwei Xie | S. Bandhakavi | Sricharan Bandhakavi | Gargi Seth | Wei-Shou Hu
[1] Taesoo Kim,et al. Blocking of acidosis-mediated apoptosis by a reduction of lactate dehydrogenase activity through antisense mRNA expression. , 2001, Biochemical and biophysical research communications.
[2] Daniel I. C. Wang,et al. Engineering of a mammalian cell line for reduction of lactate formation and high monoclonal antibody production. , 2001, Biotechnology and bioengineering.
[3] Wei-Shou Hu,et al. Molecular portrait of high productivity in recombinant NS0 cells , 2007, Biotechnology and bioengineering.
[4] R. Davis,et al. Effect of PDI Overexpression on Recombinant Protein Secretion in CHO Cells , 2000, Biotechnology progress.
[5] G. Seth,et al. Reverting cholesterol auxotrophy of NS0 cells by altering epigenetic gene silencing. , 2006, Biotechnology and bioengineering.
[6] M. Tajiri,et al. Hydrophilic affinity isolation and MALDI multiple-stage tandem mass spectrometry of glycopeptides for glycoproteomics. , 2004, Analytical chemistry.
[7] A. Dell,et al. Glycoprotein Structure Determination by Mass Spectrometry , 2001, Science.
[8] F. Cross,et al. Accurate quantitation of protein expression and site-specific phosphorylation. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[9] F. Wurm. Production of recombinant protein therapeutics in cultivated mammalian cells , 2004, Nature Biotechnology.
[10] G. Lee,et al. Initial transcriptome and proteome analyses of low culture temperature-induced expression in CHO cells producing erythropoietin. , 2006, Biotechnology and bioengineering.
[11] M. Wirth,et al. Improvement of the primary metabolism of cell cultures by introducing a new cytoplasmic pyruvate carboxylase reaction. , 1999, Biotechnology and bioengineering.
[12] T. Griffin,et al. Gel‐free mass spectrometry‐based high throughput proteomics: Tools for studying biological response of proteins and proteomes , 2006, Proteomics.
[13] M. Betenbaugh,et al. Life and death in mammalian cell culture: strategies for apoptosis inhibition. , 2004, Trends in biotechnology.
[14] J. Yates,et al. Direct analysis and identification of proteins in mixtures by LC/MS/MS and database searching at the low-femtomole level. , 1997, Analytical chemistry.
[15] F. Regnier,et al. Recent advancements in differential proteomics based on stable isotope coding. , 2005, Briefings in functional genomics & proteomics.
[16] M. Flickinger,et al. Alteration of Hybridoma Viability and Antibody Secretion in Transfectomas with Inducible Overexpression of Protein Disulfide Isomerase , 1995, Biotechnology progress.
[17] Forest M White,et al. Global phosphoproteome of HT-29 human colon adenocarcinoma cells. , 2005, Journal of proteome research.
[18] R. Chaganti,et al. Comparative genomic hybridization: an overview. , 1994, The American journal of pathology.
[19] R. Henderson,et al. Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry. , 1992, Science.
[20] F. Falciani,et al. Over-expression of hTERT in CHO K1 results in decreased apoptosis and reduced serum dependency. , 2006, Journal of biotechnology.
[21] Katie F Wlaschin,et al. Comparative transcriptional analysis of mouse hybridoma and recombinant Chinese hamster ovary cells undergoing butyrate treatment. , 2007, Journal of bioscience and bioengineering.
[22] Gary Hardiman,et al. Microarrays Technologies 2006: an overview. , 2006, Pharmacogenomics.
[23] M. Betenbaugh,et al. Part II. Overexpression of bcl-2 family members enhances survival of mammalian cells in response to various culture insults. , 2000, Biotechnology and bioengineering.
[24] Young Hwan Kim,et al. Proteome Analysis of Antibody‐Expressing CHO Cells in Response to Hyperosmotic Pressure , 2003, Biotechnology progress.
[25] L. Fu,et al. Blocking caspase‐3 activity with a U6 SnRNA promoter‐driven ribozyme enhances survivability of CHO Cells Cultured in Low Serum Medium and Production of Interferon‐β , 2004, Biotechnology and bioengineering.
[26] J. Guénet. The Mouse Genome , 2005 .
[27] Niki S. C. Wong,et al. Enhancing recombinant glycoprotein sialylation through CMP‐sialic acid transporter over expression in Chinese hamster ovary cells , 2006, Biotechnology and bioengineering.
[28] J. Yates,et al. Proteomics of organelles and large cellular structures , 2005, Nature Reviews Molecular Cell Biology.
[29] M. Betenbaugh,et al. A comparison of the properties of a Bcl-xL variant to the wild-type anti-apoptosis inhibitor in mammalian cell cultures. , 2003, Metabolic engineering.
[30] M. Betenbaugh,et al. Aven and Bcl‐xL enhance protection against apoptosis for mammalian cells exposed to various culture conditions , 2004, Biotechnology and bioengineering.
[31] Ruedi Aebersold,et al. Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry , 2005, Nature Methods.
[32] J. Yates,et al. Large-scale analysis of the yeast proteome by multidimensional protein identification technology , 2001, Nature Biotechnology.
[33] Anthony K. L. Leung,et al. Nucleolar proteome dynamics , 2005, Nature.
[34] Martin Fussenegger,et al. Controlled proliferation by multigene metabolic engineering enhances the productivity of Chinese hamster ovary cells , 1998, Nature Biotechnology.
[35] M Al-Rubeai,et al. Bcl-2 over-expression reduces growth rate and prolongs G1 phase in continuous chemostat cultures of hybridoma cells. , 1999, Biotechnology and bioengineering.
[36] Wei-Shou Hu,et al. Large scale gene expression profiling of metabolic shift of mammalian cells in culture. , 2004, Journal of biotechnology.
[37] Xiaohui S. Xie,et al. A Mammalian Organelle Map by Protein Correlation Profiling , 2006, Cell.
[38] Alexandrina Burlacu,et al. Regulation of apoptosis by Bcl‐2 family proteins , 2003, Journal of cellular and molecular medicine.
[39] M. Chung,et al. Proteomic Investigation of Metabolic Shift in Mammalian Cell Culture , 2001, Biotechnology progress.
[40] Ruedi Aebersold,et al. Quantitative mass spectrometry reveals a role for the GTPase Rho1p in actin organization on the peroxisome membrane , 2004, The Journal of cell biology.
[41] Albert J R Heck,et al. Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion. , 2003, Immunity.
[42] R. Aebersold,et al. Mass spectrometry in proteomics. , 2001, Chemical reviews.
[43] D. James,et al. Comparative proteomic analysis of GS-NS0 murine myeloma cell lines with varying recombinant monoclonal antibody production rate. , 2004, Biotechnology and bioengineering.
[44] Steven P Gygi,et al. Large-scale characterization of HeLa cell nuclear phosphoproteins. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[45] Regulation of cell cycle and productivity in NS0 cells by the over-expression of p21CIP1. , 2002 .
[46] R. Aebersold,et al. Mass spectrometry-based proteomics , 2003, Nature.
[47] W. Hancock,et al. Monitoring glycosylation pattern changes of glycoproteins using multi-lectin affinity chromatography. , 2005, Journal of chromatography. A.
[48] Piero Carninci,et al. Tag-based approaches for transcriptome research and genome annotation , 2005, Nature Methods.
[49] C. Borner. Diminished Cell Proliferation Associated with the Death-protective Activity of Bcl-2* , 1996, The Journal of Biological Chemistry.
[50] S. Gygi,et al. Evaluation of two-dimensional gel electrophoresis-based proteome analysis technology. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[51] Susan T Sharfstein,et al. Genome-wide analysis of the transcriptional response of murine hybridomas to osmotic shock. , 2006, Biotechnology and bioengineering.
[52] H. Katinger,et al. Evaluation of a genomics platform for cross‐species transcriptome analysis of recombinant CHO cells , 2006, Biotechnology Journal.
[53] Rovshan G Sadygov,et al. Large-scale database searching using tandem mass spectra: Looking up the answer in the back of the book , 2004, Nature Methods.
[54] M. Mann,et al. Stable Isotope Labeling by Amino Acids in Cell Culture, SILAC, as a Simple and Accurate Approach to Expression Proteomics* , 2002, Molecular & Cellular Proteomics.
[55] H. Katinger,et al. Effect of Increased Expression of Protein Disulfide Isomerase and Heavy Chain Binding Protein on Antibody Secretion in a Recombinant CHO Cell Line , 2008, Biotechnology progress.
[56] Erdahl T. Teber,et al. Identification of cellular changes associated with increased production of human growth hormone in a recombinant Chinese hamster ovary cell line , 2003, Proteomics.
[57] S. Elliott,et al. Glycoengineering: the effect of glycosylation on the properties of therapeutic proteins. , 2005, Journal of pharmaceutical sciences.
[58] S. Gygi,et al. Quantitative analysis of complex protein mixtures using isotope-coded affinity tags , 1999, Nature Biotechnology.
[59] O. Kon,et al. Stable expression of human alpha-2,6-sialyltransferase in Chinese hamster ovary cells: functional consequences for human erythropoietin expression and bioactivity. , 1998, Biochimica et biophysica acta.
[60] Shigeru Iida,et al. Establishment of FUT8 knockout Chinese hamster ovary cells: An ideal host cell line for producing completely defucosylated antibodies with enhanced antibody‐dependent cellular cytotoxicity , 2004, Biotechnology and bioengineering.
[61] Steven W. Taylor,et al. Global organellar proteomics. , 2003, Trends in biotechnology.
[62] G. Lee,et al. Inhibition of sodium butyrate-induced apoptosis in recombinant Chinese hamster ovary cells by constitutively expressing antisense RNA of caspase-3. , 2002, Biotechnology and bioengineering.
[63] M. Fussenegger,et al. Xbp1-based engineering of secretory capacity enhances the productivity of Chinese hamster ovary cells. , 2006, Metabolic engineering.
[64] A. Link. Multidimensional peptide separations in proteomics. , 2002, Trends in biotechnology.
[65] J. Paulson,et al. Alteration of terminal glycosylation sequences on N-linked oligosaccharides of Chinese hamster ovary cells by expression of beta-galactoside alpha 2,6-sialyltransferase. , 1989, The Journal of biological chemistry.
[66] C. Gervais,et al. Dose-dependent reduction of apoptosis in nutrient-limited cultures of NS/0 myeloma cells transfected with the E1B-19K adenoviral gene. , 1999, Biotechnology and bioengineering.
[67] J. Crespo,et al. Quantitation of changes in protein phosphorylation: A simple method based on stable isotope labeling and mass spectrometry , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[68] Ruedi Aebersold,et al. Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry , 2003, Nature Biotechnology.
[69] M. Nimtz,et al. Construction and characterization of stably transfected BHK-21 cells with human-type sialylation characteristic , 1999, Cytotechnology.
[70] K. Parker,et al. Multiplexed Protein Quantitation in Saccharomyces cerevisiae Using Amine-reactive Isobaric Tagging Reagents*S , 2004, Molecular & Cellular Proteomics.
[71] R. Philp,et al. Large-scale gene expression analysis of cholesterol dependence in NS0 cells. , 2005, Biotechnology and bioengineering.
[72] Wei-Shou Hu,et al. Engineering cells for cell culture bioprocessing--physiological fundamentals. , 2006, Advances in biochemical engineering/biotechnology.