Single-cell RNA sequencing reveals that VIM and IFITM3 are vital targets of Gengzhan Shengmai capsule to protect against cerebral ischemic injury.

[1]  Jing Zhao,et al.  Multi-omics and network pharmacology study reveals the effects of Dengzhan Shengmai capsule against neuroinflammatory injury and thrombosis induced by ischemic stroke. , 2022, Journal of ethnopharmacology.

[2]  F. Wen,et al.  Proteomic and phosphorylated proteomic landscape of injured lung in juvenile septic rats with therapeutic application of umbilical cord mesenchymal stem cells , 2022, Frontiers in Immunology.

[3]  Baohui Xu,et al.  P-Glycoprotein Aggravates Blood Brain Barrier Dysfunction in Experimental Ischemic Stroke by Inhibiting Endothelial Autophagy , 2022, Aging and disease.

[4]  Hong-Jun Yang,et al.  Integrated transcriptomics and metabolomics analysis reveals that C3 and C5 are vital targets of DuZhi Wan in protecting against cerebral ischemic injury. , 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[5]  Afaf Abdelkader,et al.  Arabic Gum Could Alleviate the Aflatoxin B1-provoked Hepatic Injury in Rat: The Involvement of Oxidative Stress, Inflammatory, and Apoptotic Pathways , 2022, Toxins.

[6]  Peng Liu,et al.  Identification of immune-related key genes in the peripheral blood of ischaemic stroke patients using a weighted gene coexpression network analysis and machine learning , 2022, Journal of Translational Medicine.

[7]  Gab Seok Kim,et al.  Increased Expression of Interferon-Induced Transmembrane 3 (IFITM3) in Stroke and Other Inflammatory Conditions in the Brain , 2022, International journal of molecular sciences.

[8]  Xiaodong Ma,et al.  Design and synthesis of novel indole and indazole-piperazine pyrimidine derivatives with anti-inflammatory and neuroprotective activities for ischemic stroke treatment. , 2022, European journal of medicinal chemistry.

[9]  Shuang He,et al.  Qishen Yiqi Dropping Pill facilitates post-stroke recovery of motion and memory loss by modulating ICAM-1-mediated neuroinflammation. , 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[10]  L. Du,et al.  Effects of Long-Term Vagus Nerve Electrical Stimulation Therapy on Acute Cerebral Infarction and Neurological Function Recovery in Post MCAO Mice , 2022, Oxidative medicine and cellular longevity.

[11]  Hongjun Yang,et al.  Guhong Injection Prevents Ischemic Stroke-Induced Neuro-Inflammation and Neuron Loss Through Regulation of C5ar1 , 2022, Frontiers in Pharmacology.

[12]  Yi Wang,et al.  Guhong injection promotes post-stroke functional recovery via attenuating cortical inflammation and apoptosis in subacute stage of ischemic stroke. , 2022, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[13]  Lu Lei,et al.  Huangqi-Honghua Combination Prevents Cerebral Infarction with Qi Deficiency and Blood Stasis Syndrome in Rats by the Autophagy Pathway , 2022, Evidence-based complementary and alternative medicine : eCAM.

[14]  Lu Cheng,et al.  Sufentanil alleviates cerebral ischemia-reperfusion injury by inhibiting inflammation and protecting the blood-brain barrier in rats , 2022, European journal of histochemistry : EJH.

[15]  W. Zhang,et al.  Integrated hepatic single-cell RNA sequencing and untargeted metabolomics reveals the immune and metabolic modulation of Qing-Fei-Pai-Du decoction in mice with coronavirus-induced pneumonia , 2022, Phytomedicine.

[16]  Yu He,et al.  Comparison of Traditional Chinese Medicine in the Long-Term Secondary Prevention for Patients with Ischemic Stroke: A Systematical Analysis , 2021, Frontiers in Pharmacology.

[17]  G. Tsivgoulis,et al.  Inflammation and Stroke Risk: A New Target for Prevention. , 2021, Stroke.

[18]  Yun Xu,et al.  AIM2 deletion enhances blood‐brain barrier integrity in experimental ischemic stroke , 2021, CNS neuroscience & therapeutics.

[19]  Feifei Guo,et al.  Proteomics and transcriptome reveal the key transcription factors mediating the protection of Panax notoginseng saponins (PNS) against cerebral ischemia/reperfusion injury. , 2021, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[20]  Jian-xun Liu,et al.  [Application prospects of single-cell transcriptome sequencing in traditional Chinese medicine research]. , 2021, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

[21]  O. Melander,et al.  Circulating Vimentin Is Associated With Future Incidence of Stroke in a Population-Based Cohort Study. , 2021, Stroke.

[22]  OUP accepted manuscript , 2021, Plant Physiology.

[23]  Zelong Zheng,et al.  Loss of GFAP and Vimentin Does Not Affect Peri-Infarct Depolarizations after Focal Cerebral Ischemia , 2020, European Neurology.

[24]  Junying Zhang,et al.  Network topology and machine learning analyses reveal microstructural white matter changes underlying Chinese medicine Dengzhan Shengmai treatment on patients with vascular cognitive impairment. , 2020, Pharmacological research.

[25]  K. Yin,et al.  Endothelium-Targeted Deletion of microRNA-15a/16-1 Promotes Poststroke Angiogenesis and Improves Long-Term Neurological Recovery , 2020, Circulation research.

[26]  F. Gao,et al.  Silencing of Long Non-coding RNA GAS5 Suppresses Neuron Cell Apoptosis and Nerve Injury in Ischemic Stroke Through Inhibiting DNMT3B-Dependent MAP4K4 Methylation , 2020, Translational Stroke Research.

[27]  J. Guldner,et al.  Prehospital Stroke Management Optimized by Use of Clinical Scoring vs Mobile Stroke Unit for Triage of Patients With Stroke: A Randomized Clinical Trial. , 2019, JAMA neurology.

[28]  A. Ou,et al.  The add-on effect of dengzhan shengmai capsules on secondary prevention of ischemic stroke: A multicentre, randomised, placebo-controlled clinical trial. , 2019, Complementary therapies in medicine.

[29]  P. Sun,et al.  Neuroprotective Effects and Mechanisms of Zhenlong Xingnao Capsule in In Vivo and In Vitro Models of Hypoxia , 2019, Front. Pharmacol..

[30]  D. Vivien,et al.  Immune Responses and Anti-inflammatory Strategies in a Clinically Relevant Model of Thromboembolic Ischemic Stroke with Reperfusion , 2019, Translational Stroke Research.

[31]  Ji Ye,et al.  [Research advance in chemical compounds,pharmacological action and clinical application of Dengzhan Shengmai Capsules]. , 2019, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

[32]  J. Lötvall,et al.  Stem Cell-Derived Exosomes as Nanotherapeutics for Autoimmune and Neurodegenerative Disorders. , 2019, ACS nano.

[33]  Benjamin B. Risk,et al.  ACE of space: estimating genetic components of high-dimensional imaging data. , 2019, Biostatistics.

[34]  B. Kissela,et al.  Inflammatory cytokines and ischemic stroke risk , 2019, Neurology.

[35]  Francesca N. Delling,et al.  Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association , 2019, Circulation.

[36]  C. Zhang,et al.  Neutrophil Membrane-Derived Nanovesicles Alleviate Inflammation To Protect Mouse Brain Injury from Ischemic Stroke. , 2019, ACS nano.

[37]  C. Justicia,et al.  Microglial cell loss after ischemic stroke favors brain neutrophil accumulation , 2018, Acta Neuropathologica.

[38]  Paul Hoffman,et al.  Integrating single-cell transcriptomic data across different conditions, technologies, and species , 2018, Nature Biotechnology.

[39]  Mark Johnson,et al.  Transsynaptic Mapping of Second-Order Taste Neurons in Flies by trans-Tango , 2017, Neuron.

[40]  Jinkwon Kim,et al.  Gray-Matter Volume Estimate Score: A Novel Semi-Automatic Method Measuring Early Ischemic Change on CT , 2015, Journal of stroke.

[41]  R. Giffard,et al.  Significance of marrow‐derived nicotinamide adenine dinucleotide phosphate oxidase in experimental ischemic stroke , 2011, Annals of neurology.

[42]  E. Kılıç,et al.  Delayed melatonin administration promotes neuronal survival, neurogenesis and motor recovery, and attenuates hyperactivity and anxiety after mild focal cerebral ischemia in mice , 2008, Journal of pineal research.

[43]  M. Chopp,et al.  Temporal Profile of in situ DNA Fragmentation after Transient Middle Cerebral Artery Occlusion in the Rat , 1995, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.