Study on the effects of monochromatic aberrations in the accommodation response by using adaptive optics.

The effect of asymmetric monochromatic aberrations in the accommodation response was studied by using an adaptive optics (AO) system. This approach permits the precise modification of ocular aberrations during accommodation. The AO system is composed of a real-time Hartmann-Shack wavefront sensor and a membrane deformable mirror with 37 independent actuators. The accommodation response was measured in two subjects with their normal aberrations and with the asymmetric aberrations terms corrected. We found a significant and systematic increase in the response accommodation time, and a reduction in the peak velocity, in both subjects when the aberrations were corrected in real time. However, neither the latency time nor the precision of the accommodation were affected. These results may indicate that the monochromatic aberrations play a role in driving the accommodation response.

[1]  P Artal,et al.  Dynamics of the eye's wave aberration. , 2001, Journal of the Optical Society of America. A, Optics, image science, and vision.

[2]  Philip B. Kruger,et al.  Accommodation Without Higher Order Monochromatic Aberrations , 2002 .

[3]  R. Sylvester-Bradley,et al.  Limits to the performance of poultry. , 2005 .

[4]  Horace W. Babcock,et al.  THE POSSIBILITY OF COMPENSATING ASTRONOMICAL SEEING , 1953 .

[5]  D R Williams,et al.  Supernormal vision and high-resolution retinal imaging through adaptive optics. , 1997, Journal of the Optical Society of America. A, Optics, image science, and vision.

[6]  I Iglesias,et al.  Closed-loop adaptive optics in the human eye. , 2001, Optics letters.

[7]  Pablo Artal,et al.  Adaptive optics simulation of intraocular lenses with modified spherical aberration. , 2004, Investigative ophthalmology & visual science.

[8]  David Williams,et al.  The arrangement of the three cone classes in the living human eye , 1999, Nature.

[9]  L M Smithline.  Accommodative response to blur. , 1974, Journal of the Optical Society of America.

[10]  C. Gray,et al.  Natural movies evoke precise responses in cat visual cortex that are not predicted from non-uniform Poisson processes , 2004 .

[11]  Pablo Artal,et al.  Adaptive optics visual simulator. , 2002, Journal of refractive surgery.

[12]  P. Artal,et al.  Adaptive-optics ultrahigh-resolution optical coherence tomography. , 2004, Optics letters.

[13]  P B Kruger,et al.  Spectral bandwidth and ocular accommodation. , 1995, Journal of the Optical Society of America. A, Optics, image science, and vision.

[14]  P Artal,et al.  Correction of the aberrations in the human eye with a liquid-crystal spatial light modulator: limits to performance. , 1998, Journal of the Optical Society of America. A, Optics, image science, and vision.

[15]  L Stark,et al.  Absence of an odd-error signal mechanism in human accommodation. , 1965, IEEE transactions on bio-medical engineering.

[16]  Philip B. Kruger,et al.  Chromatic aberration and ocular focus: Fincham revisited , 1993, Vision Research.

[17]  Pablo Artal,et al.  Membrane deformable mirror for adaptive optics: performance limits in visual optics. , 2003, Optics express.

[18]  P Artal,et al.  High-resolution imaging of the living human fovea: measurement of the intercenter cone distance by speckle interferometry. , 1989, Optics letters.

[19]  Pablo Artal,et al.  Adaptive-Optics Correction of Asymmetric Aberrations Degrades Accommodation Responses , 2002 .

[20]  G WESTHEIMER,et al.  Factors influencing accommodation responses of the human eye. , 1959, Journal of the Optical Society of America.

[21]  A. Ivanoff,et al.  About the spherical aberration of the eye. , 1956, Journal of the Optical Society of America.

[22]  Jenkins Tc.  ABERRATIONS OF THE EYE AND THEIR EFFECTS ON VISION. II. , 1963 .

[23]  Austin Roorda,et al.  Monochromatic aberrations provide an odd-error cue to focus direction. , 2002, Journal of the Optical Society of America. A, Optics, image science, and vision.

[24]  T. Jenkins,et al.  ABERRATIONS OF THE EYE AND THEIR EFFECTS ON VISION: 1. SPHERICAL ABERRATION. , 1963, The British journal of physiological optics.

[25]  David R Williams,et al.  Neural compensation for the eye's optical aberrations. , 2004, Journal of vision.

[26]  Pablo Artal,et al.  Adaptive optics with a programmable phase modulator: applications in the human eye. , 2004, Optics express.

[27]  F. Kingdom,et al.  Precision, accuracy, and range of perceived achromatic transparency. , 2001, Journal of the Optical Society of America. A, Optics, image science, and vision.

[28]  Jenkins Tc,et al.  ABERRATIONS OF THE EYE AND THEIR EFFECTS ON VISION: 1. SPHERICAL ABERRATION. , 1963 .

[29]  W N Charman,et al.  Fluctuations in accommodation: a review , 1988, Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians.

[30]  T. Hebert,et al.  Adaptive optics scanning laser ophthalmoscopy. , 2002, Optics express.

[31]  Albert V. Baez.  Is Resolving Power Independent of Wavelength Possible? An Experiment with a Sonic “Macroscope” , 1956 .

[32]  R. Weinreb,et al.  Active optical depth resolution improvement of the laser tomographic scanner. , 1989, Applied optics.

[33]  R. Dhillon,et al.  For the safe use of lasers , 1989 .

[34]  B. Singer,et al.  Improvement in retinal image quality with dynamic correction of the eye's aberrations. , 2001, Optics express.

[35]  P Artal,et al.  Analysis of the performance of the Hartmann-Shack sensor in the human eye. , 2000, Journal of the Optical Society of America. A, Optics, image science, and vision.

[36]  E F FINCHAM,et al.  The Accommodation Reflex and its Stimulus * , 1951, The Journal of physiology.

[37]  Christopher W. Tyler,et al.  Component analysis of BOLD response , 2004 .

[38]  Austin Roorda,et al.  A population study on changes in wave aberrations with accommodation. , 2004, Journal of vision.

[39]  Pablo Artal,et al.  Are optical aberrations during accommodation a significant problem for refractive surgery? , 2002, Journal of refractive surgery.