Room temperature phosphorescence determination of propranolol in pharmaceutical formulations.

A simple, rapid, and specific procedure was used for the analysis of propranolol in pharmaceutical formulations. The procedure consisted of dissolving (diluting) appropriate quantities of preparations and standards in (with) a 2 M potassium iodide-ethanol-water solution, spotting 5 microliter of each resultant solution onto filter paper disks, determining the phosphorescence intensities at room temperature, and comparing sample signal levels with those of standards. The results indicated that room temperature phosphorescence can be easily applied to the analysis of pharmaceutical formulations where active ingredients are generally contained in a wide variety of matrices.