The clinical features, diagnosis and natural history of nonalcoholic fatty liver disease.

[1]  Yoshimasa Kusano,et al.  Prevalence of fatty liver in Japanese children and relationship to obesity , 1995, Digestive Diseases and Sciences.

[2]  M. Camilo,et al.  Nonalcoholic steatohepatitis , 2005, Digestive Diseases and Sciences.

[3]  A. Lonardo,et al.  Non-Organ-Specific Autoantibodies in Nonalcoholic Fatty Liver Disease: Prevalence and Correlates , 2003, Digestive Diseases and Sciences.

[4]  H. Cortez‐Pinto,et al.  Nonalcoholic Steatohepatitis—A Long-Term Follow-Up Study: Comparison with Alcoholic Hepatitis in Ambulatory and Hospitalized Patients , 2003, Digestive Diseases and Sciences.

[5]  F. Brunetti,et al.  Liver Involvement in Obese Children (Ultrasonography and Liver Enzyme Levels at Diagnosis and During Follow-up in an Italian Population) , 1997, Digestive Diseases and Sciences.

[6]  G. Tomlinson,et al.  High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C , 2003, Hepatology.

[7]  A. McCullough.  Obesity and its nurturing effect on hepatitis C , 2003, Hepatology.

[8]  P. Hayashi,et al.  The natural history of nonalcoholic fatty liver disease: a clinical histopathological study , 2003, American Journal of Gastroenterology.

[9]  James G Kench,et al.  Long‐term outcomes of cirrhosis in nonalcoholic steatohepatitis compared with hepatitis C , 2003, Hepatology.

[10]  M. Manns,et al.  Effect of treatment with peginterferon or interferon alfa‐2b and ribavirin on steatosis in patients infected with hepatitis C , 2003, Hepatology.

[11]  R. Fisher,et al.  Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT values , 2003, Hepatology.

[12]  E. Keeffe,et al.  Elevated AST or ALT to nonalcoholic fatty liver disease: accurate predictor of disease prevalence? , 2003, American Journal of Gastroenterology.

[13]  G. Marchesini,et al.  Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome , 2003, Hepatology.

[14]  Jeanne M Clark,et al.  Defining nonalcoholic fatty liver disease: implications for epidemiologic studies. , 2003, Gastroenterology.

[15]  B. Neuschwander‐Tetri,et al.  730 NASH: clinical assessment of 501 patients from two separate academic medical centers with validation of a clinical scoring system for advanced hepatic fibrosis , 2003 .

[16]  A. Sanyal,et al.  AGA technical review on nonalcoholic fatty liver disease. , 2002, Gastroenterology.

[17]  A. McCullough,et al.  Steatohepatitis in obese individuals. , 2002, Best practice & research. Clinical gastroenterology.

[18]  Erick M Remer,et al.  The utility of radiological imaging in nonalcoholic fatty liver disease. , 2002, Gastroenterology.

[19]  C. Grunfeld,et al.  Steatosis in chronic hepatitis C: Relative contributions of obesity, diabetes mellitus, and alcohol , 2002, Hepatology.

[20]  S. Caldwell,et al.  Subacute liver failure in obese women. , 2002 .

[21]  A. Zanella,et al.  Updated Definitions of Healthy Ranges for Serum Alanine Aminotransferase Levels , 2002, Annals of Internal Medicine.

[22]  G. Loss,et al.  Is obesity an independent risk factor for hepatocellular carcinoma in cirrhosis? , 2002, Hepatology.

[23]  J. Ludwig,et al.  Hepatocellular carcinoma in patients with non-alcoholic steatohepatitis. , 2002, Journal of hepatology.

[24]  Mauro Salizzoni,et al.  Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma. , 2002, Gastroenterology.

[25]  J. Patrie,et al.  Is NASH underdiagnosed among African Americans , 2002 .

[26]  P. Giral,et al.  Survival, liver failure, and hepatocellular carcinoma in obesity‐related cryptogenic cirrhosis , 2002, Hepatology.

[27]  J. Patrie,et al.  Is NASH underdiagnosed among African Americans? , 2002, American Journal of Gastroenterology.

[28]  F. Brancati,et al.  Nonalcoholic fatty liver disease. , 2002, Gastroenterology.

[29]  A. McCullough,et al.  Diabetes mellitus, obesity, and hepatic steatosis. , 2002, Seminars in gastrointestinal disease.

[30]  A. McCullough,et al.  Update on nonalcoholic fatty liver disease. , 2002, Journal of clinical gastroenterology.

[31]  K. Lindor,et al.  Non‐alcoholic fatty liver disease , 2002, Journal of gastroenterology and hepatology.

[32]  E. Jaffe,et al.  Low‐Grade Follicular Lymphoma of the Small Intestine , 2002, Journal of clinical gastroenterology.

[33]  R. Karim,et al.  NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome , 2002, Hepatology.

[34]  E. Keeffe,et al.  Nonalcoholic fatty liver disease. , 2002, Reviews in gastroenterological disorders.

[35]  Rahul Krishnarao Patil,et al.  Ninety patients with nonalcoholic steatohepatitis: insulin resistance, familial tendency, and severity of disease , 2001, American Journal of Gastroenterology.

[36]  J. Manson,et al.  Diet, lifestyle, and the risk of type 2 diabetes mellitus in women. , 2001, The New England journal of medicine.

[37]  Z. Younossi,et al.  Cryptogenic cirrhosis and posttransplantation nonalcoholic fatty liver disease , 2001, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

[38]  M. Mattioli,et al.  Hyperferritinemia, iron overload, and multiple metabolic alterations identify patients at risk for nonalcoholic steatohepatitis. , 2001 .

[39]  L. Bianchi,et al.  Liver biopsy in elevated liver functions tests? An old question revisited. , 2001, Journal of hepatology.

[40]  P. D. James,et al.  Findings on liver biopsy to investigate abnormal liver function tests in the absence of diagnostic serology. , 2001, Journal of hepatology.

[41]  J. Dixon,et al.  Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese. , 2001, Gastroenterology.

[42]  K. Batts,et al.  Frequency of nonalcoholic steatohepatitis as a cause of advanced liver disease , 2001, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

[43]  A. Diehl,et al.  Obesity and female gender increase breath ethanol concentration: potential implications for the pathogenesis of nonalcoholic steatohepatitis. , 2001 .

[44]  R. Fisher,et al.  Development of nonalcoholic fatty liver disease after orthotopic liver transplantation for cryptogenic cirrhosis , 2001, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

[45]  K. Tsuneyama,et al.  Hepatocellular carcinoma arising in non‐alcoholic steatohepatitis , 2001, Pathology international.

[46]  G. Marchesini,et al.  Clinical Features and Natural History of Nonalcoholic Steatosis Syndromes , 2001, Seminars in liver disease.

[47]  M. Rosen,et al.  Imaging of Hepatic Steatosis , 2001, Seminars in liver disease.

[48]  C. García-Monzón,et al.  Characterization of pathogenic and prognostic factors of nonalcoholic steatohepatitis associated with obesity. , 2000, Journal of hepatology.

[49]  P. Thuluvath,et al.  Prevalence of obesity and diabetes in patients with cryptogenic cirrhosis: A case‐control study , 2000, Hepatology.

[50]  R. Paraná,et al.  Nonalcoholic steatohepatitis and hepatocellular carcinoma: natural history? , 2000, American Journal of Gastroenterology.

[51]  J. Prieto,et al.  Pathological and virological findings in patients with persistent hypertransaminasaemia of unknown aetiology , 2000, Gut.

[52]  A. Buchman,et al.  Metabolic and nutritional considerations in nonalcoholic fatty liver , 2000, Hepatology.

[53]  P. Giral,et al.  Liver fibrosis in overweight patients. , 2000, Gastroenterology.

[54]  J. Seidell,et al.  Obesity, insulin resistance and diabetes — a worldwide epidemic , 2000, British Journal of Nutrition.

[55]  M. Graif,et al.  Quantitative estimation of attenuation in ultrasound video images: correlation with histology in diffuse liver disease. , 2000, Investigative radiology.

[56]  M. Kaplan,et al.  Evaluation of abnormal liver-enzyme results in asymptomatic patients. , 2000, The New England journal of medicine.

[57]  G. Brandi,et al.  Prevalence of and Risk Factors for Hepatic Steatosis in Northern Italy , 2000, Annals of Internal Medicine.

[58]  S. Caldwell,et al.  Nonalcoholic steatohepatitis and cryptogenic cirrhosis within kindreds. , 2000, The American journal of medicine.

[59]  M. Rashid,et al.  Nonalcoholic steatohepatitis in children. , 2000, Journal of pediatric gastroenterology and nutrition.

[60]  H. Cortez‐Pinto,et al.  Non-alcoholic fatty liver: another feature of the metabolic syndrome? , 1999, Clinical nutrition.

[61]  K. Batts,et al.  Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis , 1999, Hepatology.

[62]  B. Bacon,et al.  Hepatic iron and nonalcoholic fatty liver disease , 1999, Hepatology.

[63]  T. Ben-Menachem,et al.  Prospective evaluation of unexplained chronic liver transaminase abnormalities in asymptomatic and symptomatic patients , 1999, American Journal of Gastroenterology.

[64]  H. Bonkovsky,et al.  Non-alcoholic steatohepatitis and iron: increased prevalence of mutations of the HFE gene in non-alcoholic steatohepatitis. , 1999, Journal of hepatology.

[65]  B. Neuschwander‐Tetri,et al.  Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions , 1999, American Journal of Gastroenterology.

[66]  Z. Younossi,et al.  Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. , 1999, Gastroenterology.

[67]  F. Schick,et al.  Measurement of intracellular triglyceride stores by H spectroscopy: validation in vivo. , 1999, American journal of physiology. Endocrinology and metabolism.

[68]  A. Frydén,et al.  The clinical significance of slightly to moderately increased liver transaminase values in asymptomatic patients. , 1999, Scandinavian journal of gastroenterology.

[69]  K. Lindor,et al.  The ratio of aspartate aminotransferase to alanine aminotransferase: potential value in differentiating nonalcoholic steatohepatitis from alcoholic liver disease , 1999, American Journal of Gastroenterology.

[70]  S. Caldwell,et al.  Cryptogenic cirrhosis: Clinical characterization and risk factors for underlying disease , 1999, Hepatology.

[71]  R. Riddell,et al.  Morphologic criteria applicable to biopsy specimens for effective distinction of inflammatory bowel disease from other forms of colitis and of Crohn's disease from ulcerative colitis. , 1999, Scandinavian journal of gastroenterology.

[72]  Herrine,et al.  Schiff's diseases of the liver , 1999, Gastroenterology.

[73]  C. Langlotz,et al.  Diagnostic criteria for fatty infiltration of the liver on contrast-enhanced helical CT. , 1998, AJR. American journal of roentgenology.

[74]  J. Goldblum,et al.  Nonalcoholic fatty liver disease: assessment of variability in pathologic interpretations. , 1998, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

[75]  P. Ward,et al.  Increased hepatic iron concentration in nonalcoholic steatohepatitis is associated with increased fibrosis. , 1998, Gastroenterology.

[76]  J. Fernández-Real,et al.  Serum Ferritin as a Component of the Insulin Resistance Syndrome , 1998, Diabetes Care.

[77]  F. Marumo,et al.  Nonalcoholic steatohepatitis masquerading as autoimmune hepatitis. , 1997, Journal of clinical gastroenterology.

[78]  F. Gordon,et al.  Nonalcoholic Steatohepatitis: Reply , 1997, Annals of Internal Medicine.

[79]  L Dalla Palma,et al.  Noninvasive in vivo quantitative assessment of fat content in human liver. , 1997, Journal of hepatology.

[80]  P. Schmalbrock,et al.  Introduction of fast MR imaging in the assessment of hepatic steatosis , 1997 .

[81]  G. Gores,et al.  Ursodeoxycholic acid or clofibrate in the treatment of non‐alcohol‐induced steatohepatitis: A pilot study , 1996, Hepatology.

[82]  A. Czaja,et al.  Genetic predispositions for immunological features in chronic liver diseases other than autoimmune hepatitis. , 1996, Journal of hepatology.

[83]  M. Bennett,et al.  The natural history of nonalcoholic fatty liver: A follow‐up study , 1995, Hepatology.

[84]  A. Perez-Atayde,et al.  Idiopathic steatohepatitis in childhood: a multicenter retrospective study. , 1995, The Journal of pediatrics.

[85]  G. Takada,et al.  The relationship between serum transaminase activities and fatty liver in children with simple obesity , 1995, Acta paediatrica Japonica : Overseas edition.

[86]  C. Tiribelli,et al.  Proton MR spectroscopy in quantitative in vivo determination of fat content in human liver steatosis , 1995, Journal of magnetic resonance imaging : JMRI.

[87]  W. Vogel,et al.  Prognosis in nonalcoholic steatohepatitis. , 1995, Gastroenterology.

[88]  B. Neuschwander‐Tetri,et al.  Nonalcoholic steatohepatitis: an expanded clinical entity. , 1994, Gastroenterology.

[89]  V. Runge,et al.  Contrast‐enhanced MR imaging of the liver , 1994, Journal of magnetic resonance imaging : JMRI.

[90]  C. Tiribelli,et al.  Fatty Infiltration of the Liver: Quantification by 1H Localized Magnetic Resonance Spectroscopy and Comparison with Computed Tomography , 1993, Investigative radiology.

[91]  R. Hultcrantz,et al.  Patients with persistent elevation of aminotransferases: investigation with ultrasonography, radionucleide imaging and liver biopsy , 1993, Journal of internal medicine.

[92]  H. Blom,et al.  The role of methanethiol in the pathogenesis of hepatic encephalopathy , 1991 .

[93]  L. Powell,et al.  Markers of chronic alcohol ingestion in patients with nonalcoholic steatohepatitis: An aid to diagnosis , 1991, Hepatology.

[94]  R. Buxton,et al.  Fatty infiltration of the liver: quantification with phase-contrast MR imaging at 1.5 T vs biopsy. , 1991, AJR. American journal of roentgenology.

[95]  I. Wanless,et al.  Fatty liver hepatitis (steatohepatitis) and obesity: An autopsy study with analysis of risk factors , 1990, Hepatology.

[96]  R. Hanson,et al.  The natural history of nonalcoholic steatohepatitis: A follow‐up study of forty‐two patients for up to 21 years , 1990, Hepatology.

[97]  A. M. Diehl,et al.  Is liver biopsy useful in the evaluation of patients with chronically elevated liver enzymes? , 1989, Annals of internal medicine.

[98]  Randall G. Lee,et al.  Nonalcoholic steatohepatitis: a study of 49 patients. , 1989, Human pathology.

[99]  K. Ishak,et al.  Alcohollike liver disease in nonalcoholics. A clinical and histologic comparison with alcohol-induced liver injury. , 1988, Gastroenterology.

[100]  K. Kawagoe,et al.  Comparison between nonalcoholic steatohepatitis and alcoholic hepatitis. , 1987, The American journal of gastroenterology.

[101]  J. Lemasters,et al.  Alcohol-Induced Liver Injury , 1984 .

[102]  J. Ludwig,et al.  Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. , 1980, Mayo Clinic proceedings.

[103]  C. M. Leevy.  FATTY LIVER: A STUDY OF 270 PATIENTS WITH BIOPSY PROVEN FATTY LIVER AND A REVIEW OF THE LITERATURE , 1962 .