Multimodal analysis of aged wild-type mice exposed to repeated scanning ultrasound treatments demonstrates long-term safety
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Abdalla Z. Mohamed | P. Sah | P. Bartlett | M. Pelekanos | J. Götz | F. Nasrallah | F. Turpin | D. Blackmore | Fangrong Zong | Rucha Pandit
[1] Nir Lipsman,et al. Blood–brain barrier opening in Alzheimer’s disease using MR-guided focused ultrasound , 2018, Nature Communications.
[2] M. Pelekanos,et al. Establishing sheep as an experimental species to validate ultrasound-mediated blood-brain barrier opening for potential therapeutic interventions , 2018, Theranostics.
[3] J. Götz,et al. Safety and Efficacy of Scanning Ultrasound Treatment of Aged APP23 Mice , 2018, Front. Neurosci..
[4] J. Rose,et al. Prediction of cognitive and motor development in preterm children using exhaustive feature selection and cross-validation of near-term white matter microstructure , 2017, NeuroImage: Clinical.
[5] Guy B. Williams,et al. Hippocampal Stratum Radiatum, Lacunosum, and Moleculare Sparing in Mild Cognitive Impairment. , 2017, Journal of Alzheimer's disease : JAD.
[6] Kullervo Hynynen,et al. Acute Inflammatory Response Following Increased Blood-Brain Barrier Permeability Induced by Focused Ultrasound is Dependent on Microbubble Dose , 2017, Theranostics.
[7] K. Hynynen,et al. Investigation of the Safety of Focused Ultrasound-Induced Blood-Brain Barrier Opening in a Natural Canine Model of Aging , 2017, Theranostics.
[8] A. Van der Jeugd,et al. Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse model , 2017, Brain : a journal of neurology.
[9] Neekita Jikaria,et al. Disrupting the blood–brain barrier by focused ultrasound induces sterile inflammation , 2016, Proceedings of the National Academy of Sciences.
[10] J. Götz,et al. Scanning Ultrasound (SUS) Causes No Changes to Neuronal Excitability and Prevents Age-Related Reductions in Hippocampal CA1 Dendritic Structure in Wild-Type Mice , 2016, PloS one.
[11] C. Yeh,et al. Focused Ultrasound-Induced Blood-Brain Barrier Opening: Association with Mechanical Index and Cavitation Index Analyzed by Dynamic Contrast-Enhanced Magnetic-Resonance Imaging , 2016, Scientific Reports.
[12] E. Konofagou,et al. Longitudinal Motor and Behavioral Assessment of Blood-Brain Barrier Opening with Transcranial Focused Ultrasound. , 2016, Ultrasound in medicine & biology.
[13] Fred H. Gage,et al. What is memory? The present state of the engram , 2016, BMC Biology.
[14] Jürgen Götz,et al. Ultrasound treatment of neurological diseases — current and emerging applications , 2016, Nature Reviews Neurology.
[15] M. Albert,et al. Why has therapy development for dementia failed in the last two decades? , 2016, Alzheimer's & Dementia.
[16] Vincent P. Ferrera,et al. Blood-Brain Barrier Opening in Behaving Non-Human Primates via Focused Ultrasound with Systemically Administered Microbubbles , 2015, Scientific Reports.
[17] S. Feinstein,et al. Update on the safety and efficacy of commercial ultrasound contrast agents in cardiac applications , 2015, Echo research and practice.
[18] Jürgen Götz,et al. Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer’s disease mouse model , 2015, Science Translational Medicine.
[19] Carlo Caltagirone,et al. Atrophy of presubiculum and subiculum is the earliest hippocampal anatomical marker of Alzheimer's disease , 2015, Alzheimer's & dementia.
[20] R. Graham,et al. Characterization of age-associated changes in peripheral organ and brain region weights in C57BL/6 mice , 2015, Experimental Gerontology.
[21] Kullervo Hynynen,et al. Alzheimer disease in a mouse model: MR imaging-guided focused ultrasound targeted to the hippocampus opens the blood-brain barrier and improves pathologic abnormalities and behavior. , 2014, Radiology.
[22] T. Yen,et al. Submicron-Bubble-Enhanced Focused Ultrasound for Blood–Brain Barrier Disruption and Improved CNS Drug Delivery , 2014, PloS one.
[23] Stephen M. Smith,et al. Permutation inference for the general linear model , 2014, NeuroImage.
[24] D. Butterfield,et al. Redox proteomics and the dynamic molecular landscape of the aging brain , 2014, Ageing Research Reviews.
[25] Brian B. Avants,et al. Explicit B-spline regularization in diffeomorphic image registration , 2013, Front. Neuroinform..
[26] Ulman Lindenberger,et al. Neuroscience and Biobehavioral Reviews Review Structural Brain Plasticity in Adult Learning and Development , 2022 .
[27] Kullervo Hynynen,et al. Amyloid-β plaque reduction, endogenous antibody delivery and glial activation by brain-targeted, transcranial focused ultrasound , 2013, Experimental Neurology.
[28] R. Sullivan,et al. Immature Doublecortin-Positive Hippocampal Neurons Are Important for Learning But Not for Remembering , 2013, The Journal of Neuroscience.
[29] Andreas Engvig,et al. Memory training impacts short‐term changes in aging white matter: A Longitudinal Diffusion Tensor Imaging Study , 2012, Human brain mapping.
[30] Gary F. Egan,et al. Segmentation of the C57BL/6J mouse cerebellum in magnetic resonance images , 2012, NeuroImage.
[31] Natalia Vykhodtseva,et al. Temporary disruption of the blood-brain barrier by use of ultrasound and microbubbles: safety and efficacy evaluation in rhesus macaques. , 2012, Cancer research.
[32] Yaniv Assaf,et al. Learning in the Fast Lane: New Insights into Neuroplasticity , 2012, Neuron.
[33] Gary F. Egan,et al. Segmentation of the mouse hippocampal formation in magnetic resonance images , 2011, NeuroImage.
[34] Menno P. Witter,et al. A pathophysiological framework of hippocampal dysfunction in ageing and disease , 2011, Nature Reviews Neuroscience.
[35] Elisa E Konofagou,et al. Noninvasive and localized neuronal delivery using short ultrasonic pulses and microbubbles , 2011, Proceedings of the National Academy of Sciences.
[36] Anqi Qiu,et al. Robust Automatic Rodent Brain Extraction Using 3-D Pulse-Coupled Neural Networks (PCNN) , 2011, IEEE Transactions on Image Processing.
[37] Y. Assaf,et al. Diffusion MRI of Structural Brain Plasticity Induced by a Learning and Memory Task , 2011, PloS one.
[38] Hsiao-Fang Liang,et al. Radial diffusivity predicts demyelination in ex vivo multiple sclerosis spinal cords , 2011, NeuroImage.
[39] K. Hynynen,et al. Focused-ultrasound disruption of the blood-brain barrier using closely-timed short pulses: influence of sonication parameters and injection rate. , 2011, Ultrasound in medicine & biology.
[40] Feng-Yi Yang,et al. Reversible blood-brain barrier disruption by repeated transcranial focused ultrasound allows enhanced extravasation. , 2011, Journal of controlled release : official journal of the Controlled Release Society.
[41] James J. Choi,et al. Noninvasive and Localized Blood—Brain Barrier Disruption using Focused Ultrasound can be Achieved at Short Pulse Lengths and Low Pulse Repetition Frequencies , 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[42] Y. Hong,et al. Differences in Microstructural Alterations of the Hippocampus in Alzheimer Disease and Idiopathic Normal Pressure Hydrocephalus: A Diffusion Tensor Imaging Study , 2010, American Journal of Neuroradiology.
[43] Yao-Sheng Tung,et al. Multi-modality safety assessment of blood-brain barrier opening using focused ultrasound and definity microbubbles: a short-term study. , 2010, Ultrasound in medicine & biology.
[44] L. Muftuler,et al. Microstructural Diffusion Tensor Imaging Reveals Perforant Path Degradation in Aged Humans in Vivo , 2010, Alzheimer's & Dementia.
[45] Rajiv Chopra,et al. Antibodies Targeted to the Brain with Image-Guided Focused Ultrasound Reduces Amyloid-β Plaque Load in the TgCRND8 Mouse Model of Alzheimer's Disease , 2010, PloS one.
[46] I. Hickie,et al. Cognitive training in affective disorders improves memory: a preliminary study using the NEAR approach. , 2010, Journal of affective disorders.
[47] F. Zang,et al. Role of Myo-Inositol by Magnetic Resonance Spectroscopy in Early Diagnosis of Alzheimer’s Disease in APP/PS1 Transgenic Mice , 2010, Dementia and Geriatric Cognitive Disorders.
[48] Timothy Edward John Behrens,et al. Training induces changes in white matter architecture , 2009, Nature Neuroscience.
[49] Arno Klein,et al. Evaluation of 14 nonlinear deformation algorithms applied to human brain MRI registration , 2009, NeuroImage.
[50] P. Basser,et al. In vivo measurement of axon diameter distribution in the corpus callosum of rat brain. , 2009, Brain : a journal of neurology.
[51] M. P. McDonald,et al. Endogenous anxiety and stress responses in water maze and Barnes maze spatial memory tasks , 2009, Behavioural Brain Research.
[52] K. Hynynen,et al. Effects of acoustic parameters and ultrasound contrast agent dose on focused-ultrasound induced blood-brain barrier disruption. , 2008, Ultrasound in medicine & biology.
[53] K. Hynynen,et al. Blood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index. , 2008, Ultrasound in medicine & biology.
[54] S A Small,et al. Spatio-temporal analysis of molecular delivery through the blood–brain barrier using focused ultrasound , 2007, Physics in medicine and biology.
[55] G. Allan Johnson,et al. Morphometric analysis of the C57BL/6J mouse brain , 2007, NeuroImage.
[56] Marco Bozzali,et al. Diffusion tensor MRI to investigate dementias: a brief review. , 2007, Magnetic resonance imaging.
[57] R. E. Schmidt,et al. Toward accurate diagnosis of white matter pathology using diffusion tensor imaging , 2007, Magnetic resonance in medicine.
[58] J. Raber,et al. Sex-differences in age-related cognitive decline in C57BL/6J mice associated with increased brain microtubule-associated protein 2 and synaptophysin immunoreactivity , 2006, Neuroscience.
[59] A. Pfefferbaum,et al. Diffusion tensor imaging and aging , 2006, Neuroscience & Biobehavioral Reviews.
[60] Manabu Kinoshita,et al. Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[61] Fred H. Gage,et al. Exercise Enhances Learning and Hippocampal Neurogenesis in Aged Mice , 2005, The Journal of Neuroscience.
[62] Clifford R Jack,et al. Monitoring disease progression in transgenic mouse models of Alzheimer's disease with proton magnetic resonance spectroscopy. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[63] Timothy Edward John Behrens,et al. Characterization and propagation of uncertainty in diffusion‐weighted MR imaging , 2003, Magnetic resonance in medicine.
[64] John Russell,et al. Dysmyelination Revealed through MRI as Increased Radial (but Unchanged Axial) Diffusion of Water , 2002, NeuroImage.
[65] Michael Brady,et al. Improved Optimization for the Robust and Accurate Linear Registration and Motion Correction of Brain Images , 2002, NeuroImage.
[66] Stephen M. Smith,et al. A global optimisation method for robust affine registration of brain images , 2001, Medical Image Anal..
[67] S. Provencher. Estimation of metabolite concentrations from localized in vivo proton NMR spectra , 1993, Magnetic resonance in medicine.
[68] K. Reuhl,et al. The Golgi-Cox method. , 2013, Methods in molecular biology.
[69] Ralf Seip,et al. Targeted Ultrasound-Mediated Delivery of Nanoparticles: On the Development of a New HIFU-Based Therapy and Imaging Device , 2010, IEEE Transactions on Biomedical Engineering.
[70] Yao-Sheng Tung,et al. Microbubble-Size Dependence of Focused Ultrasound-Induced Blood–Brain Barrier Opening in Mice In Vivo , 2010, IEEE Transactions on Biomedical Engineering.
[71] Y. Assaf,et al. Diffusion Tensor Imaging (DTI)-based White Matter Mapping in Brain Research: A Review , 2007, Journal of Molecular Neuroscience.
[72] James J. Choi,et al. Noninvasive, transcranial and localized opening of the blood-brain barrier using focused ultrasound in mice. , 2007, Ultrasound in medicine & biology.