Antioxidative Capacity of Melatonin

[1]  A. Mueck,et al.  Effect of melatonin and metabolites on copper-mediated oxidation of flow density lipoprotein. , 2003, British journal of clinical pharmacology.

[2]  A. Wakatsuki,et al.  Melatonin protects fetal rat brain against oxidative mitochondrial damage , 2001, Journal of pineal research.

[3]  E. Mazzon,et al.  Melatonin reduces dinitrobenzene sulfonic acid‐induced colitis , 2001, Journal of pineal research.

[4]  H. Ebelt,et al.  Scavenging effect of melatonin on hydroxyl radicals generated by alloxan , 2000, Journal of pineal research.

[5]  E. Mazzon,et al.  Protective effects of melatonin in ischemic brain injury , 2000, Journal of pineal research.

[6]  D. Bandyopadhyay,et al.  Melatonin protects against stress‐induced gastric lesions by scavenging the hydroxyl radical , 2000, Journal of pineal research.

[7]  Kazushi Watanabe,et al.  Attenuation by melatonin of human umbilical arterial vasoconstriction induced by lysophosphatidylcholine , 2000, Journal of pineal research.

[8]  G. Escames,et al.  Comparative effects of melatonin, l‐deprenyl, Trolox and ascorbate in the suppression of hydroxyl radical formation during dopamine autoxidation in vitro , 2000, Journal of pineal research.

[9]  J. Rosiak,et al.  Hydroxyl radical reaction with melatonin molecule: A computational study , 2000, Journal of pineal research.

[10]  U. Das,et al.  Preservation of the antioxidant status in chemically‐induced diabetes mellitus by melatonin , 2000, Journal of pineal research.

[11]  Kazushi Watanabe,et al.  Melatonin inhibits vasospastic action of oxidized low‐density lipoprotein in human umbilical arteries , 2000, Journal of pineal research.

[12]  J. Parrado,et al.  Protective effect of melatonin against the 1‐methyl‐4‐phenylpyridinium‐induced inhibition of Complex I of the mitochondrial respiratory chain , 2000, Journal of pineal research.

[13]  N. Harada,et al.  Protective effect of melatonin against α‐naphthylisothiocyanate‐induced liver injury in rats , 2000, Journal of pineal research.

[14]  R. Reiter,et al.  Significance of Melatonin in Antioxidative Defense System: Reactions and Products , 2000, Neurosignals.

[15]  R. Reiter,et al.  Increased levels of oxidatively damaged DNA induced by chromium(III) and H2O2: protection by melatonin and related molecules , 2000, Journal of pineal research.

[16]  G. Maestroni,et al.  Evidence for melatonin synthesis in mouse and human bone marrow cells , 2000, Journal of pineal research.

[17]  R. Reiter,et al.  Melatonin‐induced increased activity of the respiratory chain complexes I and IV can prevent mitochondrial damage induced by ruthenium red in vivo , 2000, Journal of pineal research.

[18]  P. Montilla López,et al.  Protective effect of melatonin against oxidative stress induced by ligature of extra‐hepatic biliary duct in rats: comparison with the effect of S‐adenosyl‐l‐methionine , 2000, Journal of pineal research.

[19]  Josep M. Guerrero,et al.  Serum cholesterol and lipid peroxidation are decreased by melatonin in diet‐induced hypercholesterolemic rats , 2000, Journal of pineal research.

[20]  R. Reiter,et al.  Melatonin reduces oxidative neurotoxicity due to quinolinic acid: in vitro and in vivo findings , 2000, Neuropharmacology.

[21]  Josep M. Guerrero,et al.  Ototoxicity caused by cisplatin is ameliorated by melatonin and other antioxidants , 2000, Journal of pineal research.

[22]  K. Nishida,et al.  Therapeutic effect of melatonin on carbon tetrachloride‐induced acute liver injury in rats , 2000, Journal of pineal research.

[23]  H. Ebelt,et al.  Influence of melatonin on free radical‐induced changes in rat pancreatic beta‐cells in vitro , 2000, Journal of pineal research.

[24]  Josep M. Guerrero,et al.  Neuroprotection by melatonin from glutamate‐induced excitotoxicity during development of the cerebellum in the chick embryo , 2000, Journal of pineal research.

[25]  E. Mazzon,et al.  Beneficial effects of melatonin in a rat model of splanchnic artery occlusion and reperfusion , 2000, Journal of pineal research.

[26]  Josep M. Guerrero,et al.  Ototoxicity caused by aminoglycosides is ameliorated by melatonin without interfering with the antibiotic capacity of the drugs , 2000, Journal of pineal research.

[27]  M. Rice,et al.  Ascorbate and glutathione regulation in hibernating ground squirrels , 1999, Brain Research.

[28]  R. Vlkolinský,et al.  Effects of stobadine, melatonin, and other antioxidants on hypoxia/reoxygenation-induced synaptic transmission failure in rat hippocampal slices , 1999, Brain Research.

[29]  J. González‐Gallego,et al.  Melatonin increases muscle and liver glycogen content in nonexercised and exercised rats. , 1999, Life sciences.

[30]  T. Stone,et al.  Oxidative stress as a mechanism for quinolinic acid‐induced hippocampal damage: protection by melatonin and deprenyl , 1999, British journal of pharmacology.

[31]  R. Reiter,et al.  Inhibitory effects of melatonin on ferric nitrilotriacetate-induced lipid peroxidation and oxidative DNA damage in the rat kidney. , 1999, Toxicology.

[32]  R. Reiter,et al.  Melatonin Reduces Lipid Peroxidation and Tissue Edema in Cerulein-Induced Acute Pancreatitis in Rats , 1999, Digestive Diseases and Sciences.

[33]  J Ghiso,et al.  Alzheimer β protein mediated oxidative damage of mitochondrial DNA: Prevention by melatonin , 1999, Journal of pineal research.

[34]  E. Mazzon,et al.  The protective role of endogenous melatonin in carrageenan‐induced pleurisy in the rat , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[35]  A. Rashad,et al.  Cis-platinum-induced immunosuppression: relationship to melatonin in human peripheral blood mononuclear cells. , 1999, Clinical biochemistry.

[36]  R. Reiter,et al.  Inhibitory effect of melatonin on products of lipid peroxidation resulting from chronic ethanol administration. , 1999, Alcohol and alcoholism.

[37]  S. Cuzzocrea,et al.  Role of melatonin in reduction of lipid peroxidation and peroxynitrite formation in non-septic shock induced by zymosan. , 1999, Shock.

[38]  Vijayalaxmi,et al.  Melatonin and protection from genetic damage in blood and bone marrow: Whole‐body irradiation studies in mice , 1999, Journal of pineal research.

[39]  R. Reiter,et al.  High physiological levels of melatonin in the bile of mammals. , 1999, Life sciences.

[40]  S. Weintraub,et al.  Identification of highly elevated levels of melatonin in bone marrow: its origin and significance. , 1999, Biochimica et biophysica acta.

[41]  R. Vlkolinský,et al.  Effect of stobadine, U-74389G, trolox and melatonin on resistance of rat hippocampal slices to oxidative stress. , 1999, Life sciences.

[42]  R. Liburdy,et al.  Melatonin and its precursors scavenge nitric oxide , 1999, Journal of pineal research.

[43]  Sato Honma,et al.  Melatonin induces γ-glutamylcysteine synthetase mediated by activator protein-1 in human vascular endothelial cells , 1999 .

[44]  R. Hardeland,et al.  Antioxidative effects of melatonin in Drosophila melanogaster: Antagonization of damage induced by the inhibition of catalase , 1999, Journal of pineal research.

[45]  D. Blask,et al.  Melatonin inhibition of cancer growth in vivo involves suppression of tumor fatty acid metabolism via melatonin receptor-mediated signal transduction events. , 1999, Cancer research.

[46]  Josep M. Guerrero,et al.  Melatonin inhibits expression of the inducible NO synthase II in liver and lung and prevents endotoxemia in lipopolysaccharide‐induced multiple organ dysfunction syndrome in rats , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[47]  F. Badr,et al.  Radioprotective effect of melatonin assessed by measuring chromosomal damage in mitotic and meiotic cells. , 1999, Mutation research.

[48]  E. Mazzon,et al.  Regulation of prostaglandin production in carrageenan‐induced pleurisy melatonin , 1999, Journal of pineal research.

[49]  B. Poeggeler,et al.  Potent Neuroprotective Properties against the Alzheimer β-Amyloid by an Endogenous Melatonin-related Indole Structure, Indole-3-propionic Acid* , 1999, The Journal of Biological Chemistry.

[50]  D. Pessayre,et al.  An alcoholic binge causes massive degradation of hepatic mitochondrial DNA in mice. , 1999, Gastroenterology.

[51]  S. Cadenas,et al.  Resveratrol, melatonin, vitamin E, and PBN protect against renal oxidative DNA damage induced by the kidney carcinogen KBrO3. , 1999, Free radical biology & medicine.

[52]  W. Pryor,et al.  Reaction of peroxynitrite with melatonin: A mechanistic study. , 1999, Chemical research in toxicology.

[53]  H. Bolay,et al.  Pinealectomy Aggravates and Melatonin Administration Attenuates Brain Damage in Focal Ischemia , 1999, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[54]  Joaquín J García,et al.  Pharmacological aspects of N‐acetyl‐5‐methoxytryptamine (melatonin) and 6‐methoxy‐ 1,2,3,4‐tetrahydro‐β‐carboline (pinoline) as antioxidants: Reduction of oxidative damage in brain region homogenates , 1999, Journal of pineal research.

[55]  Josep M. Guerrero,et al.  The pineal secretory product melatonin reduces hydrogen peroxide‐induced DNA damage in U‐937 cells , 1999, Journal of pineal research.

[56]  K Okumura,et al.  Zinc accumulation in adriamycin‐induced cardiomyopathy in rats: Effects of melatonin, a cardioprotective antioxidant , 1999, Journal of pineal research.

[57]  V. Anisimov,et al.  Effects of melatonin on N-nitroso-N-methylurea-induced carcinogenesis in rats and mutagenesis in vitro (Ames test and COMET assay). , 1999, Cancer letters.

[58]  K. Kumar,et al.  Melatonin: an antioxidant protects against cyclosporine-induced nephrotoxicity. , 1999, Transplantation.

[59]  Gordon H. Purser,et al.  Identification of the factors affecting the rate of deactivation of hypochlorous acid by melatonin. , 1999, Biochemical and Biophysical Research Communications - BBRC.

[60]  A. Wakatsuki,et al.  Melatonin protects against ischemia and reperfusion‐induced oxidative lipid and DNA damage in fetal rat brain , 1999, Journal of pineal research.

[61]  K. H. Kim,et al.  Melatonin and taurine reduce early glomerulopathy in diabetic rats. , 1999, Free radical biology & medicine.

[62]  D. Lahiri Melatonin affects the metabolism of the β‐amyloid precursor protein in different cell types , 1999, Journal of Pineal Research.

[63]  S. Kulkarni,et al.  Role of centrally administered melatonin and inhibitors of COX and NOS in LPS-induced hyperthermia and adipsia. , 1999, Prostaglandins, leukotrienes, and essential fatty acids.

[64]  P. Elsner,et al.  Suppression of UV-Induced Erythema by Topical Treatment with Melatonin , 1999, Neurosignals.

[65]  D. Cardinali,et al.  Effect of Melatonin in Selected Populations of Sleep-Disturbed Patients , 1999, Neurosignals.

[66]  S. Cuzzocrea,et al.  Protective Effect of Melatonin on Zymosan-Induced Cellular Damage , 1999, Neurosignals.

[67]  Vijayalaxmi,et al.  Melatonin and protection from whole-body irradiation: survival studies in mice. , 1999, Mutation research.

[68]  T. Mukherjee,et al.  Antioxidant properties of melatonin: a pulse radiolysis study. , 1999, Free radical biology & medicine.

[69]  J. Herrerias,et al.  Protective effect of melatonin on indomethacin‐induced gastric injury in rats , 1999, Journal of pineal research.

[70]  I. Antolín,et al.  Ultrastructural confirmation of neuronal protection by melatonin against the neurotoxin 6-hydroxydopamine cell damage , 1999, Brain Research.

[71]  Hwa-Jung Kim,et al.  Effects of placing micro-implants of melatonin in striatum on oxidative stress and neuronal damage mediated by N-methyl-D-aspartate (NMDA) and non-NMDA receptors , 1999, Archives of pharmacal research.

[72]  Vijayalaxmi,et al.  A novel melatonin metabolite, cyclic 3-hydroxymelatonin: a biomarker of in vivo hydroxyl radical generation. , 1998, Biochemical and biophysical research communications.

[73]  E. Mazzon,et al.  Protective effects of melatonin in zymosan-activated plasma-induced paw inflammation. , 1998, European journal of pharmacology.

[74]  D. Cardinali,et al.  Monozygotic twins with Alzheimer's disease treated with melatonin: Case report , 1998, Journal of pineal research.

[75]  R. Reiter,et al.  Melatonin protects hippocampal neurons in vivo against kainic acid‐induced damage in mice , 1998, Journal of neuroscience research.

[76]  J. Kim,et al.  Effect of melatonin on cadmium-induced hepatotoxicity in male Sprague-Dawley rats. , 1998, The Tohoku journal of experimental medicine.

[77]  N. Osborne,et al.  Melatonin counteracts ischemia-induced apoptosis in human retinal pigment epithelial cells. , 1998, Investigative ophthalmology & visual science.

[78]  A. Wakatsuki,et al.  Maternal‐fetal transfer of melatonin in pregnant women near term , 1998, Journal of pineal research.

[79]  R. Reiter,et al.  Ischemia/reperfusion‐induced arrhythmias in the isolated rat heart: Prevention by melatonin , 1998, Journal of pineal research.

[80]  F. Holsboer,et al.  Induction of NF-κB Activity during Haloperidol-Induced Oxidative Toxicity in Clonal Hippocampal Cells: Suppression of NF-κB and Neuroprotection by Antioxidants , 1998, The Journal of Neuroscience.

[81]  W. Pryor,et al.  The reaction of melatonin with peroxynitrite: formation of melatonin radical cation and absence of stable nitrated products. , 1998, Biochemical and biophysical research communications.

[82]  I. Mavelli,et al.  Melatonin decreases bone marrow and lymphatic toxicity of adriamycin in mice bearing TLX5 lymphoma. , 1998, Life sciences.

[83]  J. Cadet,et al.  Melatonin attenuates methamphetamine‐induced toxic effects on dopamine and serotonin terminals in mouse brain , 1998, Synapse.

[84]  R. Reiter Oxidative damage in the central nervous system: protection by melatonin , 1998, Progress in Neurobiology.

[85]  J. Barrett,et al.  Melatonin attenuates hydrogen peroxide toxicity in MCF7 cells only at pharmacological concentrations. , 1998, Biochemical and biophysical research communications.

[86]  R. Reiter,et al.  2-Nitropropane-induced lipid peroxidation: antitoxic effects of melatonin. , 1998, Toxicology.

[87]  V. Anisimov,et al.  Modulatory effects of melatonin on genotoxic response of reference mutagens in the Ames test and the comet assay. , 1998, Mutation research.

[88]  R. Reiter Cytoprotective properties of melatonin: presumed association with oxidative damage and aging. , 1998, Nutrition.

[89]  P. Montilla,et al.  Oxidative stress in diabetic rats induced by streptozotocin: Protective effects of melatonin , 1998, Journal of pineal research.

[90]  S. Cuzzocrea,et al.  Protective effect of melatonin on cellular energy depletion mediated by peroxynitrite and poly (ADP‐ribose) synthetase activation in a non‐septic shock model induced by zymosan in the rat , 1998, Journal of pineal research.

[91]  P. Montilla,et al.  Protective role of melatonin and retinol palmitate in oxidative stress and hyperlipidemic nephropathy induced by adriamycin in rats , 1998, Journal of pineal research.

[92]  S. Budd,et al.  Mitochondria and neuronal glutamate excitotoxicity. , 1998, Biochimica et biophysica acta.

[93]  Vijayalaxmi,et al.  Melatonin: possible mechanisms involved in its 'radioprotective' effect. , 1998, Mutation research.

[94]  M. M. Esteban,et al.  Inhibition of cell proliferation: A mechanism likely to mediate the prevention of neuronal cell death by melatonin , 1998, Journal of pineal research.

[95]  J. Rosiak,et al.  Melatonin as a hydroxyl radical scavenger , 1998, Journal of pineal research.

[96]  M. Plotkine,et al.  Protective effect of melatonin in a model of traumatic brain injury in mice , 1998, Journal of pineal research.

[97]  A. Papas,et al.  Antioxidant transport by the human placenta. , 1998, Clinical nutrition.

[98]  D. Schwindt,et al.  Topical melatonin in combination with vitamins E and C protects skin from ultraviolet‐induced erythema: a human study in vivo , 1998, The British journal of dermatology.

[99]  H. Baik,et al.  Melatonin protects 6‐OHDA‐induced neuronal death of nigrostriatal dopaminergic system , 1998, Neuroreport.

[100]  Kazunori Hayashi,et al.  Melatonin, a pineal hormone with antioxidant property, protects against adriamycin cardiomyopathy in rats , 1998 .

[101]  P. Ulański,et al.  Reactions of melatonin with radicals in deoxygenated aqueous solution , 1998 .

[102]  J. Martín,et al.  Effect of melatonin on methamphetamine- and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity and methamphetamine-induced behavioral sensitization , 1998, Neuropharmacology.

[103]  L. Facci,et al.  Melatonin prevents the delayed death of hippocampal neurons induced by enhanced excitatory neurotransmission and the nitridergic pathway , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[104]  S. Daya,et al.  Melatonin plays a protective role in quinolinic acid-induced neurotoxicity in the rat hippocampus , 1998, Journal of Chemical Neuroanatomy.

[105]  R. Reiter,et al.  The efficacy of vitamin E and melatonin as antioxidants against lipid peroxidation in rat retinal homogenates , 1998, Journal of pineal research.

[106]  K. S. Yoon,et al.  Melatonin protects nigral dopaminergic neurons from 1-methyl-4-phenylpyridinium (MPP+) neurotoxicity in rats , 1998, Neuroscience Letters.

[107]  M. M. Esteban,et al.  Melatonin prevents apoptosis induced by 6‐hydroxydopamine in neuronal cells: Implications for Parkinson's disease , 1998, Journal of pineal research.

[108]  R. Reiter,et al.  δ‐Aminolevulinic acid‐induced lipid peroxidation in rat kidney and liver is attenuated by melatonin: An in vitro and in vivo study , 1998 .

[109]  F. Lezoualc’h,et al.  N‐acetyl‐serotonin (normelatonin) and melatonin protect neurons against oxidative challenges and suppress the activity of the transcription factor NF‐κB , 1998, Journal of pineal research.

[110]  C. Soto,et al.  Inhibition of Alzheimer β-Fibrillogenesis by Melatonin* , 1998, The Journal of Biological Chemistry.

[111]  J. Taljaard,et al.  Melatonin prevents β‐amyloid‐induced lipid peroxidation , 1998 .

[112]  T. Kullisaar,et al.  Comparison of the antioxidant activity of melatonin and pinoline in vitro , 1998, Journal of pineal research.

[113]  M. Anwar,et al.  Potential protective effects of melatonin on bone marrow of rats exposed to cytotoxic drugs. , 1998, Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.

[114]  D. Hu,et al.  Pulse radiolysis studies of melatonin and chloromelatonin. , 1998, Journal of photochemistry and photobiology. B, Biology.

[115]  J. Cadet,et al.  Invited Review Free radicals and the pathobiology of brain dopamine systems , 1998, Neurochemistry International.

[116]  W. Fadel,et al.  In vivo and in vitro evaluation of the mutagenic potential of carbamazepine: does melatonin have anti-mutagenic activity? , 1998, Toxicology.

[117]  A. Vercesi,et al.  Ruthenium red-catalyzed degradation of peroxides can prevent mitochondrial oxidative damage induced by either tert-butyl hydroperoxide or inorganic phosphate. , 1998, Archives of biochemistry and biophysics.

[118]  M. Bear,et al.  Effects of the Metabotropic Glutamate Receptor Antagonist MCPG on Phosphoinositide Turnover and Synaptic Plasticity in Visual Cortex , 1998, The Journal of Neuroscience.

[119]  A. Batlle,et al.  In vivo protection by melatonin against δ‐aminolevulinic acid‐induced oxidative damage and its antioxidant effect on the activity of haem enzymes , 1998, Journal of pineal research.

[120]  T. Nyokong,et al.  The interaction of melatonin and its precursors with aluminium, cadmium, copper, iron, lead, and zinc: An adsorptive voltammetric study , 1998, Journal of pineal research.

[121]  L. Facci,et al.  Melatonin maintains glutathione homeostasis in kainic acid‐exposed rat brain tissues , 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[122]  D. Dijk,et al.  Melatonin and the Circadian Regulation of Sleep Initiation, Consolidation, Structure, and the Sleep EEG , 1997, Journal of biological rhythms.

[123]  S. Ledoux,et al.  The Amyloid β Protein Induces Oxidative Damage of Mitochondrial DNA , 1997 .

[124]  P. Saxena,et al.  Melatonin in feverfew and other medicinal plants , 1997, The Lancet.

[125]  R. Hardeland,et al.  New actions of melatonin and their relevance to biometeorology , 1997, International journal of biometeorology.

[126]  L. Rybak,et al.  Protection by 4-methylthiobenzoic acid against cisplatin-induced ototoxicity: antioxidant system. , 1997, Pharmacology & toxicology.

[127]  H. Manev,et al.  In Vitro and In Vivo Protective Effects of Melatonin against Glutamate Oxidative Stress and Neurotoxicity a , 1997, Annals of the New York Academy of Sciences.

[128]  R. Reiter,et al.  Prophylactic Actions of Melatonin in Oxidative Neurotoxicity , 1997, Annals of the New York Academy of Sciences.

[129]  R. Reiter,et al.  Melatonin protects against lipid peroxidation induced by δ-aminolevulinic acid in rat cerebellum, cortex and hippocampus , 1997, Neuroscience.

[130]  L. Iacovitti,et al.  Melatonin rescues dopamine neurons from cell death in tissue culture models of oxidative stress , 1997, Brain Research.

[131]  N. Osborne,et al.  Melatonin protects primary cultures of rat cortical neurones from NMDA excitotoxicity and hypoxia/reoxygenation , 1997, Brain Research.

[132]  V. Motilva,et al.  Melatonin protects against gastric ischemia‐reperfusion injury in rats , 1997, Journal of pineal research.

[133]  S. Cuzzocrea,et al.  Protective effect of melatonin in carrageenan‐induced models of local inflammation: Relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity , 1997, Journal of pineal research.

[134]  E. Hahn,et al.  The role of melatonin and L‐tryptophan in prevention of acute gastric lesions induced by stress, ethanol, ischemia, and aspirin , 1997, Journal of pineal research.

[135]  M. Uhr,et al.  Neuroprotective potential of aromatic alcohols against oxidative cell death , 1997, FEBS letters.

[136]  Daniel Steinberg,et al.  Low Density Lipoprotein Oxidation and Its Pathobiological Significance* , 1997, The Journal of Biological Chemistry.

[137]  R. Reiter,et al.  Melatonin in Relation to Cellular Antioxidative Defense Mechanisms , 1997, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

[138]  R. Reiter,et al.  Acutely administered melatonin reduces oxidative damage in lung and brain induced by hyperbaric oxygen. , 1997, Journal of applied physiology.

[139]  E. Sewerynek,et al.  Melatonin prevents increases in neural nitric oxide and cyclic GMP production after transient brain ischemia and reperfusion in the Mongolian gerbil (Meriones Unguiculatus) , 1997, Journal of pineal research.

[140]  A. Battle,et al.  Melatonin's antioxidant protection against δ‐aminolevulinic acid‐induced oxidative damage in rat cerebellum , 1997, Journal of pineal research.

[141]  S. Cuzzocrea,et al.  Melatonin effects on inhibition of thirst and fever induced by lipopolysaccharide in rat. , 1997, European journal of pharmacology.

[142]  A. Shaikh,et al.  Melatonin protects bovine cerebral endothelial cells from hyperoxia-induced DNA damage and death , 1997, Neuroscience Letters.

[143]  Z. Qian,et al.  Differential behaviour of cell membranes towards iron-induced oxidative damage and the effects of melatonin. , 1997, Biological signals.

[144]  Josep M. Guerrero,et al.  Inhibition of cerebellar nitric oxide synthase and cyclic GMP production by melatonin via complex formation with calmodulin , 1997, Journal of cellular biochemistry.

[145]  S. Ueno,et al.  Potent protective effect of melatonin on chromium(VI)-induced DNA single-strand breaks, cytotoxicity, and lipid peroxidation in primary cultures of rat hepatocytes. , 1997, Toxicology and applied pharmacology.

[146]  Josep M. Guerrero,et al.  Melatonin prevents changes in microsomal membrane fluidity during induced lipid peroxidation , 1997, FEBS letters.

[147]  B. Volpe,et al.  Melatonin administration protects CA1 hippocampal neurons after transient forebrain ischemia in rats , 1997, Brain Research.

[148]  M. Zembala,et al.  Gastroprotective activity of melatonin and its precursor, L-tryptophan, against stress-induced and ischaemia-induced lesions is mediated by scavenge of oxygen radicals. , 1997, Scandinavian journal of gastroenterology.

[149]  G. Nisticó,et al.  Suppressive effect of melatonin administration on ethanol‐induced gastroduodenal injury in rats in vivo , 1997, British journal of pharmacology.

[150]  G. Loo,et al.  Melatonin inhibits oxidative modification of human low‐density lipoprotein , 1997, Journal of pineal research.

[151]  N. Osborne,et al.  Retinal neurones containing kainate receptors are influenced by exogenous kainate and ischaemia while neurones lacking these receptors are not — melatonin counteracts the effect of ischaemia and kainate , 1997, Brain Research.

[152]  Z. R. Li,et al.  Cataractogenesis and lipid peroxidation in newborn rats treated with buthionine sulfoximine: Preventive actions of melatonin , 1997, Journal of pineal research.

[153]  Kazushi Watanabe,et al.  Melatonin inhibits vasopastic action of hydrogen peroxide in human umbilical artery , 1997 .

[154]  M. Zembala,et al.  Melatonin affords protection against gastric lesions induced by ischemia-reperfusion possibly due to its antioxidant and mucosal microcirculatory effects. , 1997, European journal of pharmacology.

[155]  R. Reiter,et al.  Melatonin Prevents Death of Neuroblastoma Cells Exposed to the Alzheimer Amyloid Peptide , 1997, The Journal of Neuroscience.

[156]  J. Scaiano,et al.  The Excited States of Melatonin , 1997 .

[157]  K. Hirata,et al.  Administration of melatonin and related indoles prevents exercise-induced cellular oxidative changes in rats. , 1997, Biological signals.

[158]  D. Anderson,et al.  Hepatic leukostasis and hypoxic stress in adhesion molecule-deficient mice after gut ischemia/reperfusion. , 1997, The Journal of clinical investigation.

[159]  Vijayalaxmi,et al.  Melatonin and radioprotection from genetic damage: in vivo/in vitro studies with human volunteers. , 1996, Mutation research.

[160]  H. Manev,et al.  Increased brain damage after stroke or excitotoxic seizures in melatonin‐deficient rats , 1996, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[161]  M. Meltz,et al.  EFFECT OF MELATONIN ON NF‐κB DNA‐BINDING ACTIVITY IN THE RAT SPLEEN , 1996 .

[162]  A. M. Lefer,et al.  The role of nitric oxide and cell adhesion molecules on the microcirculation in ischaemia-reperfusion. , 1996, Cardiovascular research.

[163]  F. Lezoualc’h,et al.  Melatonin prevents oxidative stress‐induced cell death in hippocampal cells , 1996, Neuroreport.

[164]  H. Yamamoto,et al.  Antagonistic effect of melatonin against cyanide-induced seizures and acute lethality in mice. , 1996, Toxicology letters.

[165]  P. Elsner,et al.  Suppression of UV-induced erythema by topical treatment with melatonin (N-acetyl-5-methoxytryptamine). A dose response study , 1996, Archives of Dermatological Research.

[166]  H. Manev,et al.  Protective effect of melatonin against hippocampal dna damage induced by intraperitoneal administration of kainate to rats , 1996, Neuroscience.

[167]  G. Nisticó,et al.  Melatonin affords protection against kainate-induced in vitro lipid peroxidation in brain. , 1996, European journal of pharmacology.

[168]  R. Reiter,et al.  Melatonin and structurally-related, endogenous indoles act as potent electron donors and radical scavengers in vitro. , 1996, Redox report : communications in free radical research.

[169]  P. Marchiafava,et al.  Melatonin prevents ischemia reperfusion injury in hamster cheek pouch microcirculation. , 1996, Cardiovascular research.

[170]  R. Hardeland,et al.  Melatonin in Algae and Higher Plants - Possible New Roles as a Phytohormone and Antioxidant , 1996 .

[171]  H. Manev,et al.  Neuroprotection by melatonin from kainate‐induced excitotoxicity in rats , 1996, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[172]  A. Wirz-Justice,et al.  Melationin: Nature's Soporific? , 1996, Journal of Sleep Research.

[173]  I. Antolín,et al.  Neurohormone melatonin prevents cell damage: effect on gene expression for antioxidant enzymes , 1996, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[174]  S. Damjanovich,et al.  Melatonin protects LDL from oxidation but does not prevent the apolipoprotein derivatization. , 1996, Biochemical and biophysical research communications.

[175]  M. Currie,et al.  Evidence of peroxynitrite involvement in the carrageenan-induced rat paw edema. , 1996, European journal of pharmacology.

[176]  Josep M. Guerrero,et al.  Melatonin reduces nitric oxide synthase activity in rat hypothalamus , 1996, Journal of pineal research.

[177]  Takuro Suzuki,et al.  Tissue changes in glutathione metabolism and lipid peroxidation induced by swimming are partially prevented by melatonin. , 1996, Pharmacology & toxicology.

[178]  F. Holsboer,et al.  Oxidative stress-resistant cells are protected against haloperidol toxicity , 1996, Brain Research.

[179]  Vijayalaxmi,et al.  Effect of melatonin on mitotic and proliferation indices, and sister chromatid exchange in human blood lymphocytes. , 1996, Mutation research.

[180]  G. Maestroni,et al.  Role of the pineal gland and melatonin in the development of autoimmune diabetes in non‐obese diabetic mice , 1996, Journal of pineal research.

[181]  G. Nisticó,et al.  Paraquat toxicity and oxidative damage. Reduction by melatonin. , 1996, Biochemical pharmacology.

[182]  R. Reiter Functional aspects of the pineal hormone melatonin in combating cell and tissue damage induced by free radicals. , 1996, European journal of endocrinology.

[183]  Hiro‐aki Yamamoto,et al.  Preventive effect of melatonin against cyanide-induced seizures and lipid peroxidation in mice , 1996, Neuroscience Letters.

[184]  R. Reiter,et al.  Lipopolysaccharide-induced DNA damage is greatly reduced in rats treated with the pineal hormone melatonin , 1996, Molecular and Cellular Endocrinology.

[185]  G. Maestroni,et al.  Melatonin as a therapeutic agent in experimental endotoxic shock , 1996, Journal of pineal research.

[186]  G. Paolisso,et al.  Oxidative Stress and Diabetic Vascular Complications , 1996, Diabetes Care.

[187]  M. Ebadi,et al.  Oxidative stress and antioxidant therapy in Parkinson's disease , 1996, Progress in Neurobiology.

[188]  M. Meltz,et al.  The neurohormone melatonin inhibits cytokine, mitogen and ionizing radiation induced NF-kappa B. , 1995, Biochemistry and molecular biology international.

[189]  R. Reiter,et al.  Melatonin reduces both basal and bacterial lipopolysaccharide-induced lipid peroxidation in vitro. , 1995, Free radical biology & medicine.

[190]  R. Reiter,et al.  Melatonin stimulates the activity of the detoxifying enzyme glutathione peroxidase in several tissues of chicks , 1995, Journal of pineal research.

[191]  R. Reiter,et al.  Melatonin reduces kainate‐induced lipid peroxidation in homogenates of different brain regions , 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[192]  R. Reiter,et al.  Melatonin counteracts lipid peroxidation induced by carbon tetrachloride but does not restore glucose‐6 phosphatase activity , 1995, Journal of pineal research.

[193]  G. Bubenik,et al.  Melatonin reduces the severity of dextran‐induced colitis in mice , 1995, Journal of pineal research.

[194]  R. Atkins,et al.  Kt/V in CAPD by different estimations of V. , 1995, Kidney international.

[195]  R. Reiter,et al.  Melatonin administration prevents lipopolysaccharide‐induced oxidative damage in phenobarbital‐treated animals , 1995, Journal of cellular biochemistry.

[196]  Vijayalaxmi,et al.  Marked reduction of radiation-induced micronuclei in human blood lymphocytes pretreated with melatonin. , 1995, Radiation research.

[197]  I. Charles,et al.  Altered immune responses in mice lacking inducible nitric oxide synthase , 1995, Nature.

[198]  A. Mendelow,et al.  Experimental stroke and neuroprotection in the aging rat brain. , 1995, Stroke.

[199]  C. Carlberg,et al.  The orphan receptor family RZR/ROR, melatonin and 5‐lipoxygenase: An unexpected relationship , 1995, Journal of pineal research.

[200]  H. Laborit,et al.  Oxygen free radicals, melatonin, and aging , 1995, Experimental Gerontology.

[201]  R. Reiter,et al.  Melatonin stimulates brain glutathione peroxidase activity , 1995, Neurochemistry International.

[202]  H. Manev,et al.  Melatonin protects neurons from singlet oxygen‐induced apoptosis , 1995, Journal of pineal research.

[203]  B. Rosen,et al.  Involvement of Free Radicals in Excitotoxicity In Vivo , 1995, Journal of neurochemistry.

[204]  Burkhard Poeggeler,et al.  On the primary functions of melatonin in evolution: Mediation of photoperiodic signals in a unicell, photooxidation, and scavenging of free radicals * , 1995, Journal of pineal research.

[205]  H. Manev,et al.  Melatonin protects primary cultures of cerebellar granule neurons from kainate but not from N-methyl-d-aspartate excitotoxicity , 1995, Experimental Neurology.

[206]  M. Bleavins,et al.  Cynomolgus monkeys (Macaca fascicularis) in preclinical immune function safety testing: development of a delayed-type hypersensitivity procedure. , 1995, Toxicology.

[207]  R. Reiter,et al.  Melatonin in edible plants identified by radioimmunoassay and by high performance liquid chromatography‐mass spectrometry , 1995, Journal of pineal research.

[208]  R. Reiter,et al.  Melatonin—A Highly Potent Endogenous Radical Scavenger and Electron Donor: New Aspects of the Oxidation Chemistry of this Indole Accessed in vitro a , 1994, Annals of the New York Academy of Sciences.

[209]  B. Poeggeler,et al.  Inhibitory effect of melatonin on cataract formation in newborn rats: Evidence for an antioxidative role for melatonin , 1994, Journal of pineal research.

[210]  D. Müller-Wieland,et al.  Melatonin inhibits LDL receptor activity and cholesterol synthesis in freshly isolated human mononuclear leukocytes. , 1994, Biochemical and biophysical research communications.

[211]  S. Heales,et al.  Effects of 1‐Methyl‐4‐Phenylpyridinium on Isolated Rat Brain Mitochondria: Evidence for a Primary Involvement of Energy Depletion , 1994, Journal of neurochemistry.

[212]  G. Perry,et al.  Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease. , 1994, The American journal of pathology.

[213]  L. Riddiford,et al.  Evidence of a stimulatory effect of cyclic AMP on corpus allatum activity in Manduca sexta , 1994, Molecular and Cellular Endocrinology.

[214]  J. Schacht,et al.  Sulfhydryl compounds and antioxidants inhibit cytotoxicity to outer hair cells of a gentamicin metabolite in vitro , 1994, Hearing Research.

[215]  P. Isakson,et al.  In vivo characterization of zymosan-induced mouse peritoneal inflammation. , 1994, The Journal of pharmacology and experimental therapeutics.

[216]  I. Fridovich,et al.  Free radicals in cutaneous biology. , 1994, The Journal of investigative dermatology.

[217]  G. Huether Melatonin Synthesis in the Gastrointestinal Tract and the Impact of Nutritional Factors on Circulating Melatonin , 1994, Annals of the New York Academy of Sciences.

[218]  J. Nurnberger,et al.  Melatonin-like immunoreactivity in the presence of different chemicals as determined by the radioimmunoassay. , 1994, Biochemical medicine and metabolic biology.

[219]  R. Reiter,et al.  Both physiological and pharmacological levels of melatonin reduce DNA adduct formation induced by the carcinogen safrole. , 1994, Carcinogenesis.

[220]  R T Blickenstaff,et al.  Potential radioprotective agents. 1. Homologs of melatonin. , 1994, Journal of pharmaceutical sciences.

[221]  P. Morgan,et al.  Melatonin receptors: Localization, molecular pharmacology and physiological significance , 1994, Neurochemistry International.

[222]  G. Sperk,et al.  Kainic acid seizures in the rat , 1994, Progress in Neurobiology.

[223]  R. Reiter,et al.  Nuclear localization of melatonin in different mammalian tissues: Immunocytochemical and radioimmunoassay evidence , 1993, Journal of cellular biochemistry.

[224]  J. Coyle,et al.  Oxidative stress, glutamate, and neurodegenerative disorders. , 1993, Science.

[225]  N. Laver,et al.  Early epithelial lesions in cataracts of GSH-depleted mouse pups. , 1993, Experimental eye research.

[226]  T. Stone,et al.  Neuropharmacology of quinolinic and kynurenic acids. , 1993, Pharmacological reviews.

[227]  A. Batlle,et al.  Porphyrins, porphyrias, cancer and photodynamic therapy--a model for carcinogenesis. , 1993, Journal of photochemistry and photobiology. B, Biology.

[228]  R. Reiter,et al.  Distribution of melatonin in mammalian tissues: The relative importance of nuclear versus cytosolic localization , 1993, Journal of pineal research.

[229]  R. Reiter,et al.  The pineal hormone melatonin inhibits DNA-adduct formation induced by the chemical carcinogen safrole in vivo. , 1993, Cancer letters.

[230]  D. Bredesen,et al.  bcl-2 inhibits death of central neural cells induced by multiple agents. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[231]  R. Reiter,et al.  Melatonin, hydroxyl radical‐mediated oxidative damage, and aging: A hypothesis , 1993, Journal of pineal research.

[232]  M. Dizdaroglu Oxidative damage to DNA in mammalian chromatin. , 1992, Mutation research.

[233]  A. Murakami,et al.  Hydroxyl radical formation by UV-irradiated epidermal cells. , 1992, Journal of biochemistry.

[234]  N. Robakis,et al.  Immunohistochemical evidence of antioxidant stress in Alzheimer's disease , 1992 .

[235]  R. Reiter,et al.  The ageing pineal gland and its physiological consequences , 1992, BioEssays : news and reviews in molecular, cellular and developmental biology.

[236]  S. Pang,et al.  The effect of food deprivation on brain and gastrointestinal tissue levels of tryptophan, serotonin, 5‐hydroxyindoleacetic acid, and melatonin , 1992, Journal of pineal research.

[237]  J. Besharse,et al.  Rhythmic regulation of retinal melatonin: Metabolic pathways, neurochemical mechanisms, and the ocular circadian clock , 1991, Cellular and Molecular Neurobiology.

[238]  N. Zisapel,et al.  Melatonin binding proteins identified in the rat brain by affinity labeling , 1991, FEBS letters.

[239]  A. A. Taylor,et al.  Inflammation in the course of early myocardial ischemia , 1991, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[240]  R. Goris,et al.  Does selective decontamination of the gastrointestinal tract prevent multiple organ failure? An experimental study. , 1991, Archives of surgery.

[241]  R. Reiter,et al.  Pineal melatonin: cell biology of its synthesis and of its physiological interactions. , 1991, Endocrine reviews.

[242]  J. Cadet,et al.  Regional effects of 6-hydroxydopamine (6-OHDA) on free radical scavengers in rat brain , 1989, Brain Research.

[243]  S. Hayashi,et al.  Presence of a Distinct 24‐Hour Melatonin Rhythm in the Ventricular Cerebrospinal Fluid of the Goat , 1989, Journal of pineal research.

[244]  H. R. Andersen,et al.  Effect of cadmium chloride on hepatic lipid peroxidation in mice. , 1988, Pharmacology & toxicology.

[245]  R. Reiter,et al.  Melatonin in the lacrimal gland: first demonstration and experimental manipulation. , 1988, Biochemical and biophysical research communications.

[246]  A. Novelli,et al.  Glutamate becomes neurotoxic via the N-methyl-d-aspartate receptor when intracellular energy levels are reduced , 1988, Brain Research.

[247]  K. Howes,et al.  Sexual Dimorphism in N-Acetyltransferase Activity, Hydroxyindole-O-methyltransferase Activity, and Melatonin Content in the Harderian Gland of Syrian Hamsters: Changes following Gonadectomy 1 , 1988, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[248]  N. Mori,et al.  Effects of melatonin on genetic hypercholesterolemia in rats. , 1988, Atherosclerosis.

[249]  A. Stern,et al.  Mechanism of Kainate Toxicity to Cerebellar Neurons In Vitro Is Analogous to Reperfusion Tissue Injury , 1987, Journal of neurochemistry.

[250]  P. Ghezzi,et al.  Role of reactive oxygen intermediates in the hepatotoxicity of endotoxin. , 1986, Immunopharmacology.

[251]  C. Knox,et al.  Concentrations of vitamin E in various neuroanatomical regions and subcellular fractions, and the uptake of vitamin E by specific areas, of rat brain. , 1984, Biochimica et biophysica acta.

[252]  V. Vihko,et al.  Lipid peroxidation in exercise myopathy. , 1983, Experimental and molecular pathology.

[253]  W. Malaisse Alloxan toxicity to the pancreatic B-cell. A new hypothesis. , 1982, Biochemical pharmacology.

[254]  S. Marklund,et al.  Copper- and zinc-containing superoxide dismutase, manganese-containing superoxide dismutase, catalase, and glutathione peroxidase in normal and neoplastic human cell lines and normal human tissues. , 1982, Cancer research.

[255]  R. Reiter The pineal and its hormones in the control of reproduction in mammals. , 1980, Endocrine reviews.

[256]  I. Ifrim,et al.  Adriamycin: the role of lipid peroxidation in cardiac toxicity and tumor response. , 1977, Science.

[257]  M. Rollag,et al.  Melatonin: daily cycle in plasma and cerebrospinal fluid of calves. , 1977, Science.

[258]  R. Reiter Pineal control of a seasonal reproductive rhythm in male golden hamsters exposed to natural daylight and temperature. , 1973, Endocrinology.

[259]  A. Lerner,et al.  ISOLATION OF MELATONIN, THE PINEAL GLAND FACTOR THAT LIGHTENS MELANOCYTES1 , 1958 .

[260]  R. Reiter,et al.  Melatonin reduces the increase in 8-hydroxy-deoxyguanosine levels in the brain and liver of kainic acid-treated rats , 2004, Molecular and Cellular Biochemistry.

[261]  C. Ribuot,et al.  Protective effects of melatonin against ischemia-reperfusion injury in the isolated rat heart. , 2000, Life sciences.

[262]  R. Reiter,et al.  An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: implications for Alzheimer's disease , 2000, Journal of Neural Transmission.

[263]  R. Cozzi,et al.  Inhibitory action of melatonin on H2O2- and cyclophosphamide-induced DNA damage. , 1999, Mutagenesis.

[264]  R. Reiter Oxidative damage to nuclear DNA: amelioration by melatonin. NEL Review. , 1999, Neuro endocrinology letters.

[265]  H. Manev,et al.  Opposite effects of pinealectomy and melatonin administration on brain damage following cerebral focal ischemia in rat. , 1998, Restorative neurology and neuroscience.

[266]  G. Maestroni,et al.  New T Helper Cell Opioid Cytokines as Mediators of the Immunological and Hematopoietic Action of Melatonin , 1997 .

[267]  N. Huang,et al.  Hydroxyl radical formation in hyperglycemic rats during middle cerebral artery occlusion/reperfusion. , 1997, Free radical biology & medicine.

[268]  R. Reiter,et al.  Antioxidant actions of melatonin. , 1997, Advances in pharmacology.

[269]  K. Scharffetter-Kochanek,et al.  Photoaging of the connective tissue of skin: its prevention and therapy. , 1997, Advances in pharmacology.

[270]  M. Muñoz,et al.  Hyperlipidemic nephropathy induced by adriamycin: effect of melatonin administration. , 1997, Nephron.

[271]  P. Yu,et al.  R(-)-deprenyl potentiates dopamine-induced cytotoxicity toward catecholaminergic neuroblastoma SH-SY5Y cells. , 1997, Toxicology and applied pharmacology.

[272]  R. Reiter,et al.  Memorial Symposium at Royal Society of Medicine, London, September 13 1997: Both melatonin and a putative nuclear melatonin receptor agonist CGP 52608 stimulate glutathione peroxidase and glutathione reductase activities in mouse brain in vivo , 1997 .

[273]  C. Chignell,et al.  Reaction of melatonin and related indoles with hydroxyl radicals: EPR and spin trapping investigations. , 1997, Free radical biology & medicine.

[274]  C. Carlberg,et al.  Nuclear Signalling of Melatonin , 1997 .

[275]  D. Bandyopadhyay,et al.  Hydroxyl radical is the major causative factor in stress-induced gastric ulceration. , 1997, Free radical biology & medicine.

[276]  J. Joseph,et al.  Oxidative damage caused by free radicals produced during catecholamine autoxidation: protective effects of O-methylation and melatonin. , 1996, Free radical biology & medicine.

[277]  R. Reiter,et al.  Evaluation of the antioxidant activity of melatonin in vitro. , 1996, Free radical biology & medicine.

[278]  H. Puy,et al.  Increased delta aminolevulinic acid and decreased pineal melatonin production. A common event in acute porphyria studies in the rat. , 1996, The Journal of clinical investigation.

[279]  R. Korthuis,et al.  Physiologic mechanisms of postischemic tissue injury. , 1995, Annual review of physiology.

[280]  R. Reiter,et al.  Retinal lipid peroxidation in vitro is inhibited by melatonin , 1995 .

[281]  Vijayalaxmi,et al.  Melatonin protects human blood lymphocytes from radiation-induced chromosome damage. , 1995, Mutation research.

[282]  E. Hall,et al.  Direct measurement of hydroxyl radicals, lipid peroxidation, and blood-brain barrier disruption following unilateral cortical impact head injury in the rat. , 1994, Journal of neurotrauma.

[283]  H. Puy,et al.  Decreased nocturnal plasma melatonin levels in patients with recurrent acute intermittent porphyria attacks. , 1993, Life sciences.

[284]  R. Reiter,et al.  A brief survey of pineal gland-immune system interrelationships. , 1992, Endocrine research.

[285]  M. Sugiyama Role of physiological antioxidants in chromium(VI)-induced cellular injury. , 1992, Free radical biology & medicine.

[286]  P. Lees,et al.  A comparative study of the cellular, exudative and histological responses to carrageenan, dextran and zymosan in the mouse. , 1991, International journal of tissue reactions.

[287]  R. Reiter,et al.  Melatonin receptors: current status, facts, and hypotheses. , 1990, Life sciences.

[288]  S. Rahimtoola,et al.  The hibernating myocardium. , 1989, American heart journal.

[289]  L. Oberley Free radicals and diabetes. , 1988, Free radical biology & medicine.

[290]  J. Ward,et al.  DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability. , 1988, Progress in nucleic acid research and molecular biology.

[291]  S. Szabó,et al.  Mechanisms of mucosal injury in the stomach and duodenum: time-sequence analysis of morphologic, functional, biochemical and histochemical studies. , 1987, Scandinavian journal of gastroenterology. Supplement.

[292]  J. Vanecek,et al.  Pineal melatonin in hibernating and aroused golden hamsters (Mesocricetus auratus). , 1984, Comparative biochemistry and physiology. A, Comparative physiology.