Robotic laboratory automation platform based on mobile agents for clinical chemistry

In this research, we propose an innovative robotic platform for clinical tests suitable for small- or medium-sized laboratories using small-sized multiple mobile robots and a robotic arm. The robotic platform, called “BioRobot Platform,” allows us to run a test process more flexibly than traditional sequential test procedures using conveyor belts by simultaneously conducting various clinical tests through multiple mobile agents. It also improves productivity (the number of tests conducted in time) by having controllable throughput according to amount of tests. Moreover, to operate the entire hardware and several mobile agents concurrently, the various algorithms related to robotic technologies such as motion control, localization, and path planning algorithm are applied to the platform. To evaluate the performance of the BioRobot Platform, various control methods are implemented, which provides parallel processing and scalability. The feasibility of the BioRobot Platform with three mobile robotic agents is validated through preliminary experiments.

[1]  Wan Kyun Chung,et al.  Development of flexible laboratory automation platform using Mobile Agents in the clinical laboratory , 2008, 2008 IEEE International Conference on Automation Science and Engineering.

[2]  M G Bissell,et al.  Leveling the playing field. The economics of robotics in the hospital clinical lab. , 1998, MLO: medical laboratory observer.

[3]  Sung Moon Jin,et al.  Point-of-Care Test Equipment for Flexible Laboratory Automation , 2012, 2012 IEEE International Conference on Automation Science and Engineering (CASE).

[4]  Jung Woo Kim,et al.  Automatic Scheduling Algorithm for Personalized Clinical Test , 2006, 2006 SICE-ICASE International Joint Conference.

[5]  R S Seaberg,et al.  The role of total laboratory automation in a consolidated laboratory network. , 2000, Clinical chemistry.

[6]  Wan Kyun Chung,et al.  Global localization for a small mobile robot using magnetic patterns , 2010, 2010 IEEE International Conference on Robotics and Automation.

[7]  Robin A Felder,et al.  Evaluation of an automated preanalytical robotic workstation at two academic health centers. , 2002, Clinical chemistry.

[8]  T Kageoka,et al.  Total laboratory automation in Japan. Past, present, and the future. , 1998, Clinica chimica acta; international journal of clinical chemistry.

[9]  Byung June Choi,et al.  Localization Using Magnetic Patterns for Autonomous Mobile Robot , 2014 .

[10]  R A Felder,et al.  Robotics and the changing face of the clinical laboratory. , 1996, Clinical chemistry.

[11]  S Bauer,et al.  Laboratory automation, Part 2. Total lab automation: system design. , 1995, MLO: medical laboratory observer.

[12]  Charles H. Fisher,et al.  ACAPELLA-5K, a high-throughput automated genome and chemical analysis system , 2003, Proceedings 2003 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS 2003) (Cat. No.03CH37453).

[13]  Wan Kyun Chung,et al.  Robotic laboratory automation platform based on mobile agents for flexible clinical tests , 2010, 2010 IEEE International Conference on Automation Science and Engineering.

[14]  Miklós Báthor,et al.  Scheduling a Flexible, Open-Architecture Robotic Workstation under LabWindows , 2005 .

[15]  Sebastian Thrun,et al.  Anytime Dynamic A*: An Anytime, Replanning Algorithm , 2005, ICAPS.

[16]  Sven Koenig,et al.  Improved fast replanning for robot navigation in unknown terrain , 2002, Proceedings 2002 IEEE International Conference on Robotics and Automation (Cat. No.02CH37292).

[17]  S Bauer,et al.  Laboratory automation, Part 1. Total laboratory automation: a view of the 21st century. , 1995, MLO: medical laboratory observer.

[18]  Wan Kyun Chung,et al.  Development of an Improved Scheduling Algorithm for Lab Test Operations on a Small-Size Bio Robot Platform , 2010 .

[19]  R A Felder,et al.  Modular robotic workcell for coagulation analysis. , 2000, Clinical chemistry.

[20]  G J Kost,et al.  Automation. Part 1. Modular stepwise automation and the future of diagnostic testing. , 1998, MLO: medical laboratory observer.

[21]  James E. Boyd,et al.  Robotic Laboratory Automation , 2002, Science.

[22]  Reinhold Schäfer Concepts for Dynamic Scheduling in the Laboratory , 2004 .

[23]  R A Felder,et al.  Modular workcells: modern methods for laboratory automation. , 1998, Clinica chimica acta; international journal of clinical chemistry.

[24]  Wan Kyun Chung,et al.  Development of Flexible BioRobot Platform for Integrated Clinical Test , 2008 .

[25]  R Felder,et al.  Robotic automation of coagulation analysis. , 1998, Clinica chimica acta; international journal of clinical chemistry.

[26]  Sven Koenig,et al.  Fast replanning for navigation in unknown terrain , 2005, IEEE Transactions on Robotics.