A Non-rigid Registration Method for Dynamic Contrast Enhancement Breast MRI

During several minutes acquisition of dynamic contrast enhancement breast magnetic resonance images(DCE breast MRI), patient movement and respiration activity can lead to misunderstanding enhancing regions, causing longer reading times and less clear diagnoses. It is necessary for MRI to be spatially registered before diagnoses. The paper presents a non-rigid registration method for DCE breast MRI which employs improved demon algorithm. Polynomial and least square method is used to correct intensity change between pre and post contrast images before registration of demon method. The experiment results show that the presented approach works better than original demon algorithm and free form deformation (FFD) algorithm.

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