FLT3-ITD AML cells The FLT3 and Pim kinases inhibitor SGI-1776 preferentially target

http://bloodjournal.hematologylibrary.org/content/119/7/1791.full.html Updated information and services can be found at: http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#repub_requests Information about reproducing this article in parts or in its entirety may be found online at: http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#reprints Information about ordering reprints may be found online at: http://bloodjournal.hematologylibrary.org/site/subscriptions/index.xhtml Information about subscriptions and ASH membership may be found online at:

[1]  K. Honjo,et al.  Is Toso an antiapoptotic protein or an Fc receptor for IgM? , 2012, Blood.

[2]  T. Mak,et al.  Toso regulates the balance between apoptotic and nonapoptotic death receptor signaling by facilitating RIP1 ubiquitination. , 2011, Blood.

[3]  Varsha Gandhi,et al.  Mechanisms of cytotoxicity to Pim kinase inhibitor, SGI-1776, in acute myeloid leukemia. , 2011, Blood.

[4]  Stefan Knapp,et al.  PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers , 2010, Haematologica.

[5]  Kathleen M Murphy,et al.  FLT3-mutant allelic burden and clinical status are predictive of response to FLT3 inhibitors in AML. , 2010, Blood.

[6]  T. Kitamura,et al.  Identity of the elusive IgM Fc receptor (FcμR) in humans , 2009, The Journal of experimental medicine.

[7]  P. Zarrinkar,et al.  AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML). , 2009, Blood.

[8]  S. Burdach,et al.  CD25 Blockade protects T Cells from Activation‐induced Cell Death (AICD) via Maintenance of TOSO Expression , 2009, Scandinavian journal of immunology.

[9]  J. Tamburini,et al.  Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia. , 2009, Blood.

[10]  Lisa S. Chen,et al.  Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells. , 2008, Blood.

[11]  Chunaram Choudhary,et al.  Tyrosine Phosphorylation Regulates Maturation of Receptor Tyrosine Kinases , 2005, Molecular and Cellular Biology.

[12]  C. Jacob,et al.  The Mouse Cell Surface Protein TOSO Regulates Fas/Fas Ligand-induced Apoptosis through Its Binding to Fas-associated Death Domain* , 2005, Journal of Biological Chemistry.

[13]  C. Lacombe,et al.  Critical role for PI 3-kinase in the control of erythropoietin-induced erythroid progenitor proliferation. , 2003, Blood.

[14]  E. Solary,et al.  Essential role for the p110delta isoform in phosphoinositide 3-kinase activation and cell proliferation in acute myeloid leukemia. , 2005, Blood.