FLT3-ITD AML cells The FLT3 and Pim kinases inhibitor SGI-1776 preferentially target
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[1] K. Honjo,et al. Is Toso an antiapoptotic protein or an Fc receptor for IgM? , 2012, Blood.
[2] T. Mak,et al. Toso regulates the balance between apoptotic and nonapoptotic death receptor signaling by facilitating RIP1 ubiquitination. , 2011, Blood.
[3] Varsha Gandhi,et al. Mechanisms of cytotoxicity to Pim kinase inhibitor, SGI-1776, in acute myeloid leukemia. , 2011, Blood.
[4] Stefan Knapp,et al. PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers , 2010, Haematologica.
[5] Kathleen M Murphy,et al. FLT3-mutant allelic burden and clinical status are predictive of response to FLT3 inhibitors in AML. , 2010, Blood.
[6] T. Kitamura,et al. Identity of the elusive IgM Fc receptor (FcμR) in humans , 2009, The Journal of experimental medicine.
[7] P. Zarrinkar,et al. AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML). , 2009, Blood.
[8] S. Burdach,et al. CD25 Blockade protects T Cells from Activation‐induced Cell Death (AICD) via Maintenance of TOSO Expression , 2009, Scandinavian journal of immunology.
[9] J. Tamburini,et al. Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia. , 2009, Blood.
[10] Lisa S. Chen,et al. Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells. , 2008, Blood.
[11] Chunaram Choudhary,et al. Tyrosine Phosphorylation Regulates Maturation of Receptor Tyrosine Kinases , 2005, Molecular and Cellular Biology.
[12] C. Jacob,et al. The Mouse Cell Surface Protein TOSO Regulates Fas/Fas Ligand-induced Apoptosis through Its Binding to Fas-associated Death Domain* , 2005, Journal of Biological Chemistry.
[13] C. Lacombe,et al. Critical role for PI 3-kinase in the control of erythropoietin-induced erythroid progenitor proliferation. , 2003, Blood.
[14] E. Solary,et al. Essential role for the p110delta isoform in phosphoinositide 3-kinase activation and cell proliferation in acute myeloid leukemia. , 2005, Blood.