Transformation of organic compounds by fungal spores.

Publisher Summary The capacity of microorganisms to synthesize rapidly large quantities of protoplasm and reserve materials and to secrete a large variety of useful metabolites has led to industrial processes that can be classified arbitrarily into three categories. Microorganisms are grown on suitable media and harvested for their cells or for their reserve materials for different purposes such as the production of yeasts destined for bakery and the preparation of microbial fats, carbohydrates, and proteins for human and animal consumption. Microorganisms are also cultivated for the valuable excretory metabolites they sometimes accumulate, such as alcohols, organic acids, vitamins, antibiotics, and enzymes. The scope of this review is to describe the “spore process” as applied to the transformation of steroids and some other organic compounds and to point out factors involved in the production of sufficient quantities of spores. Although this process has been studied mainly for fungal spores, it can also be applied to the spores of certain streptomycetes.

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