An enhanced chemopreventive effect of methyl donor S-adenosylmethionine in combination with 25-hydroxyvitamin D in blocking mammary tumor growth and metastasis

[1]  J. Manson,et al.  Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease , 2019, The New England journal of medicine.

[2]  S. Ramaswamy,et al.  TSR-033, a Novel Therapeutic Antibody Targeting LAG-3, Enhances T-Cell Function and the Activity of PD-1 Blockade In Vitro and In Vivo , 2018, Molecular Cancer Therapeutics.

[3]  Nathaniel D. Tippens,et al.  methyl-ATAC-seq measures DNA methylation at accessible chromatin , 2018, bioRxiv.

[4]  M. Szyf,et al.  Methyl donor S-adenosylmethionine (SAM) supplementation attenuates breast cancer growth, invasion, and metastasis in vivo; therapeutic and chemopreventive applications , 2017, Oncotarget.

[5]  C. Fuchs,et al.  SUNSHINE: Randomized double-blind phase II trial of vitamin D supplementation in patients with previously untreated metastatic colorectal cancer. , 2017 .

[6]  Hui Meng,et al.  Overexpression of Interferon Regulatory Factor 7 (IRF7) Reduces Bone Metastasis of Prostate Cancer Cells in Mice , 2017, Oncology research.

[7]  A. Laghezza,et al.  Bone-Seeking Matrix Metalloproteinase-2 Inhibitors Prevent Bone Metastatic Breast Cancer Growth , 2017, Molecular Cancer Therapeutics.

[8]  W. Muller,et al.  Tumoral Vitamin D Synthesis by CYP27B1 1-α-Hydroxylase Delays Mammary Tumor Progression in the PyMT-MMTV Mouse Model and Its Action Involves NF-κB Modulation. , 2016, Endocrinology.

[9]  Gwendolyn M. Jang,et al.  Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding. , 2015, Cell host & microbe.

[10]  M. Beckmann,et al.  Abstract B32: Inhibiting DNA methylation causes an interferon response in cancer via dsRNA including endogenous retroviruses , 2016 .

[11]  M. Szyf,et al.  DNA demethylation and invasive cancer: implications for therapeutics , 2015, British journal of pharmacology.

[12]  M. Szyf,et al.  Pharmacological methyl group donors block skeletal metastasis in vitro and in vivo , 2015, British journal of pharmacology.

[13]  Yu Fan,et al.  BioXpress: an integrated RNA-seq-derived gene expression database for pan-cancer analysis , 2015, Database J. Biol. Databases Curation.

[14]  Steven L Salzberg,et al.  HISAT: a fast spliced aligner with low memory requirements , 2015, Nature Methods.

[15]  A. Jemal,et al.  Global cancer statistics, 2012 , 2015, CA: a cancer journal for clinicians.

[16]  M. Szyf,et al.  S-adenosylmethionine blocks osteosarcoma cells proliferation and invasion in vitro and tumor metastasis in vivo: therapeutic and diagnostic clinical applications , 2015, Cancer medicine.

[17]  W. Muller,et al.  Chemoprevention Activity of 25-Hydroxyvitamin D in the MMTV-PyMT Mouse Model of Breast Cancer , 2014, Cancer Prevention Research.

[18]  W. Huber,et al.  Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.

[19]  M. Szyf,et al.  Synergistic effects of combined DNA methyltransferase inhibition and MBD2 depletion on breast cancer cells; MBD2 depletion blocks 5-aza-2'-deoxycytidine-triggered invasiveness. , 2014, Carcinogenesis.

[20]  Paul Theodor Pyl,et al.  HTSeq—a Python framework to work with high-throughput sequencing data , 2014, bioRxiv.

[21]  Z. Crăiniceanu,et al.  The Synergistic Biologic Activity of Oleanolic and Ursolic Acids in Complex with Hydroxypropyl-γ-Cyclodextrin , 2014, Molecules.

[22]  Björn Usadel,et al.  Trimmomatic: a flexible trimmer for Illumina sequence data , 2014, Bioinform..

[23]  S. Mohr,et al.  Meta-analysis of vitamin D sufficiency for improving survival of patients with breast cancer. , 2014, Anticancer research.

[24]  A. Beck,et al.  The MMTV-PyVT Transgenic Mouse as a Multistage Model for Mammary Carcinoma and the Efficacy of Antineoplastic Treatment , 2013 .

[25]  L. Verlinden,et al.  Antineoplastic effects of 1,25(OH)2D3 and its analogs in breast, prostate and colorectal cancer. , 2013, Endocrine-related cancer.

[26]  J. Mathers,et al.  Nutritional factors and gender influence age-related DNA methylation in the human rectal mucosa , 2012, Aging cell.

[27]  Ralf Herwig,et al.  The ConsensusPathDB interaction database: 2013 update , 2012, Nucleic Acids Res..

[28]  J. Knight,et al.  Vitamin D Intake Is Negatively Associated with Promoter Methylation of the Wnt Antagonist Gene DKK1 in a Large Group of Colorectal Cancer Patients , 2012, Nutrition and cancer.

[29]  Paul J Hertzog,et al.  Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape , 2012, Nature Medicine.

[30]  B. Fingleton,et al.  An Osteoblast-Derived Proteinase Controls Tumor Cell Survival via TGF-beta Activation in the Bone Microenvironment , 2012, PloS one.

[31]  M. Gültekin,et al.  Inhibition of angiogenesis by S-adenosylmethionine. , 2011, Biochemical and biophysical research communications.

[32]  Vilppu J Tuominen,et al.  ImmunoRatio: a publicly available web application for quantitative image analysis of estrogen receptor (ER), progesterone receptor (PR), and Ki-67 , 2010, Breast Cancer Research.

[33]  Shelly C. Lu,et al.  S-Adenosylmethionine and Methylthioadenosine Inhibit Cellular FLICE Inhibitory Protein Expression and Induce Apoptosis in Colon Cancer Cells , 2009, Molecular Pharmacology.

[34]  C. Davis.  Vitamin D and cancer: current dilemmas and future research needs. , 2008, The American journal of clinical nutrition.

[35]  B. Fingleton,et al.  Effect of ablation or inhibition of stromal matrix metalloproteinase-9 on lung metastasis in a breast cancer model is dependent on genetic background. , 2008, Cancer research.

[36]  D. Trump,et al.  Vitamin D signalling pathways in cancer: potential for anticancer therapeutics , 2007, Nature Reviews Cancer.

[37]  T. Rohan.  Epidemiological studies of vitamin D and breast cancer. , 2007, Nutrition reviews.

[38]  Pablo Tamayo,et al.  Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[39]  M. Guy,et al.  Autocrine Metabolism of Vitamin D in Normal and Malignant Breast Tissue , 2005, Clinical Cancer Research.

[40]  A. Stoll,et al.  Bioavailability and Lack of Toxicity of S‐Adenosyl‐l‐Methionine (SAMe) in Humans , 2004, Pharmacotherapy.

[41]  Jeffrey W Pollard,et al.  Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases. , 2003, The American journal of pathology.

[42]  G. Evan,et al.  Proliferation, cell cycle and apoptosis in cancer , 2001, Nature.

[43]  R. Coleman.  Skeletal complications of malignancy , 1997, Cancer.

[44]  M. Prichard,et al.  A three-dimensional model to analyze drug-drug interactions. , 1990, Antiviral research.

[45]  T. Bottiglieri,et al.  The Switch Mechanism and the Bipolar/Unipolar Dichotomy , 1989, British Journal of Psychiatry.

[46]  R. Rubens,et al.  The clinical course of bone metastases from breast cancer. , 1987, British Journal of Cancer.

[47]  J. Moore,et al.  Bone Metastasis , 1982, British Journal of Cancer.

[48]  S. Rabbani,et al.  Targeting DNA Hypomethylation in Malignancy by Epigenetic Therapies. , 2019, Advances in experimental medicine and biology.

[49]  A. Jemal,et al.  Global Cancer Statistics , 2011 .

[50]  S. Singletary,et al.  Breast Cancer Staging: Working With the Sixth Edition of the AJCC Cancer Staging Manual , 2006, CA: a cancer journal for clinicians.

[51]  A. Jemal,et al.  Global cancer statistics , 2011, CA: a cancer journal for clinicians.