Neural antecedents of social decision-making in a partner choice task.

Experiments in financial decision-making point to two complementary processes that encode prospective gain and loss preceding the choice to purchase consumer goods. These processes involve the nucleus accumbens (NAcc) and the right anterior insula, respectively. The current experiment used functional MRI to investigate whether these regions served a similar function during an analogous social decision-making task without the influence of monetary outcomes. In this task, subjects chose partners based on face stimuli of varying attractiveness (operationalizing value) and ratings of compatibility with the participant (operationalizing likelihood of rejection). The NAcc responded to anticipated gain; the right anterior insula responded to compatibility, but not in a manner that suggests an analogy to anticipated cost. Logistic regression modeling demonstrated that both regions predicted subsequent choice above and beyond the influence of group attractiveness ratings or compatibility alone. Although the function of the insula may differ between tasks, these results suggest that financial and social decision-making recruit a similar network of brain regions.

[1]  G. Rhodes.  The evolutionary psychology of facial beauty. , 2006, Annual review of psychology.

[2]  Colin Camerer,et al.  Social neuroeconomics: the neural circuitry of social preferences , 2007, Trends in Cognitive Sciences.

[3]  James M. Kilner,et al.  Brain systems for assessing facial attractiveness , 2007, Neuropsychologia.

[4]  P. Glimcher,et al.  Choice from Non-Choice: Predicting Consumer Preferences from Blood Oxygenation Level-Dependent Signals Obtained during Passive Viewing , 2011, The Journal of Neuroscience.

[5]  J. Langlois,et al.  Maxims or myths of beauty? A meta-analytic and theoretical review. , 2000, Psychological bulletin.

[6]  Russell A Poldrack,et al.  Common and dissociable prefrontal loci associated with component mechanisms of analogical reasoning. , 2010, Cerebral cortex.

[7]  Alan C. Evans,et al.  A Three-Dimensional Statistical Analysis for CBF Activation Studies in Human Brain , 1992, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[8]  Daeyeol Lee,et al.  Ubiquity and Specificity of Reinforcement Signals throughout the Human Brain , 2011, Neuron.

[9]  P. Glimcher,et al.  The neural correlates of subjective value during intertemporal choice , 2007, Nature Neuroscience.

[10]  D. Perrett,et al.  Beauty in a smile: the role of medial orbitofrontal cortex in facial attractiveness , 2003, Neuropsychologia.

[11]  B Fischl,et al.  A sulcal depth-based anatomical parcellation of the cerebral cortex. , 2009, NeuroImage.

[12]  Brian Knutson,et al.  Individual Differences in Insular Sensitivity During Loss Anticipation Predict Avoidance Learning , 2008, Psychological science.

[13]  G. Loewenstein,et al.  Neural Predictors of Purchases , 2007, Neuron.

[14]  D. Ariely,et al.  Beautiful Faces Have Variable Reward Value fMRI and Behavioral Evidence , 2001, Neuron.

[15]  D H Brainard,et al.  The Psychophysics Toolbox. , 1997, Spatial vision.

[16]  J. Rilling,et al.  The neuroscience of social decision-making. , 2011, Annual review of psychology.

[17]  J. Tanaka,et al.  The NimStim set of facial expressions: Judgments from untrained research participants , 2009, Psychiatry Research.

[18]  Rebecca Saxe,et al.  For Love or Money: A Common Neural Currency for Social and Monetary Reward , 2008, Neuron.

[19]  V. Michel,et al.  An Automatic Valuation System in the Human Brain: Evidence from Functional Neuroimaging , 2009, Neuron.

[20]  Nikos Makris,et al.  Automatically parcellating the human cerebral cortex. , 2004, Cerebral cortex.

[21]  N. Sadato,et al.  Processing of Social and Monetary Rewards in the Human Striatum , 2008, Neuron.

[22]  Corianne Rogalsky,et al.  Increased activation in the right insula during risk-taking decision making is related to harm avoidance and neuroticism , 2003, NeuroImage.

[23]  Peter N. C. Mohr,et al.  Neural Processing of Risk , 2010, The Journal of Neuroscience.

[24]  T. Robbins,et al.  Decision-making processes following damage to the prefrontal cortex. , 2002, Brain : a journal of neurology.

[25]  G. Pagnoni,et al.  The neural correlates of the affective response to unreciprocated cooperation , 2008, Neuropsychologia.

[26]  S. Haber,et al.  The Reward Circuit: Linking Primate Anatomy and Human Imaging , 2010, Neuropsychopharmacology.

[27]  D G Pelli,et al.  The VideoToolbox software for visual psychophysics: transforming numbers into movies. , 1997, Spatial vision.

[28]  M. Paulus,et al.  An Insular View of Anxiety , 2006, Biological Psychiatry.

[29]  Brian Knutson,et al.  Neural Antecedents of Financial Decisions , 2007, The Journal of Neuroscience.

[30]  P. Montague,et al.  Neural Economics and the Biological Substrates of Valuation , 2002, Neuron.

[31]  Alan G. Sanfey,et al.  Social Decision-Making: Insights from Game Theory and Neuroscience , 2007, Science.

[32]  D G Pelli,et al.  Pixel independence: measuring spatial interactions on a CRT display. , 1997, Spatial vision.

[33]  Daeyeol Lee.  Game theory and neural basis of social decision making , 2008, Nature Neuroscience.

[34]  Karl J. Friston,et al.  Dissociable Neural Responses in Human Reward Systems , 2000, The Journal of Neuroscience.

[35]  C. Zink,et al.  Know Your Place: Neural Processing of Social Hierarchy in Humans , 2008, Neuron.

[36]  Denise C. Park,et al.  A lifespan database of adult facial stimuli , 2004, Behavior research methods, instruments, & computers : a journal of the Psychonomic Society, Inc.

[37]  Camelia M. Kuhnen,et al.  The Neural Basis of Financial Risk Taking , 2005, Neuron.

[38]  Brian Knutson,et al.  Anticipation of Increasing Monetary Reward Selectively Recruits Nucleus Accumbens , 2001, The Journal of Neuroscience.

[39]  Anders M. Dale,et al.  Automatic parcellation of human cortical gyri and sulci using standard anatomical nomenclature , 2010, NeuroImage.